Hepatocyte growth factor (HGF) or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells...
23 KB (2,635 words) - 06:03, 24 August 2024
Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity...
59 KB (6,727 words) - 06:01, 27 October 2024
epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family...
60 KB (6,879 words) - 14:26, 16 July 2024
Artemin Growth differentiation factor-9 (GDF9) Hepatocyte growth factor (HGF) Hepatoma-derived growth factor (HDGF) Insulin Insulin-like growth factors Insulin-like...
10 KB (1,131 words) - 19:14, 31 March 2024
The fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of...
8 KB (827 words) - 22:08, 3 December 2023
A growth factor receptor is a receptor that binds to a growth factor. Growth factor receptors are the first stop in cells where the signaling cascade...
5 KB (591 words) - 15:41, 29 April 2024
Fibroblast growth factor receptor 2 (FGFR-2) also known as CD332 (cluster of differentiation 332) is a protein that in humans is encoded by the FGFR2 gene...
14 KB (1,745 words) - 09:02, 15 July 2024
is known as mechano-growth factor (MGF). Laron syndrome (LS), also known as growth hormone insensitivity or growth hormone receptor deficiency (GHRD),...
35 KB (4,575 words) - 09:00, 2 November 2024
Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival...
27 KB (3,064 words) - 04:17, 25 November 2024
Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family...
13 KB (1,563 words) - 09:00, 13 March 2024
Crizotinib (category Receptor tyrosine kinase inhibitors)
cell lung carcinoma (NSCLC). Crizotinib inhibits the c-Met/Hepatocyte growth factor receptor (HGFR) tyrosine kinase, which is involved in the oncogenesis...
22 KB (1,866 words) - 05:42, 2 November 2024
Hepatocyte nuclear factor 4 alpha (HNF4A) also known as NR2A1 (nuclear receptor subfamily 2, group A, member 1) is a nuclear receptor that in humans is...
18 KB (2,230 words) - 15:35, 22 August 2024
Fibroblast growth factor receptor 1 (FGFR-1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome...
44 KB (5,003 words) - 07:11, 15 October 2024
The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate...
14 KB (1,689 words) - 01:31, 19 August 2024
Platelet-derived growth factor receptor A, also termed CD140a, is a receptor located on the surface of a wide range of cell types. The protein is encoded...
29 KB (3,354 words) - 17:01, 9 December 2023
through different receptor mechanisms. Furthermore, they do not always induce cellular transformation, and are not the only growth factors that induce cellular...
6 KB (596 words) - 05:15, 1 January 2024
Fibroblast growth factor receptor 3 (FGFR-3) is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as CD333 (cluster...
17 KB (1,845 words) - 01:41, 9 October 2024
Growth factor receptor inhibitors (growth factor inhibitors, growth factor receptor blockers, growth factor blockers, growth factor receptor antagonists...
4 KB (381 words) - 22:35, 2 December 2023
Insulin-like growth factor 2 receptor (IGF2R), also called the cation-independent mannose-6-phosphate receptor (CI-MPR) is a protein that in humans is...
13 KB (1,664 words) - 16:27, 25 May 2024
nerve growth factor. p75NTR is a neurotrophic factor receptor. Neurotrophic factor receptors bind Neurotrophins including Nerve growth factor, Neurotrophin-3...
37 KB (4,235 words) - 21:48, 19 November 2024
The insulin-like growth factor 1 (IGF-1) receptor is a protein found on the surface of human cells. It is a transmembrane receptor that is activated by...
29 KB (3,603 words) - 16:26, 25 May 2024
Vascular endothelial growth factor (VEGF, /vɛdʒˈɛf/), originally known as vascular permeability factor (VPF), is a signal protein produced by many cells...
40 KB (4,578 words) - 12:30, 10 September 2024
fibroblast growth factor receptors (FGFRs). FGF1 is also known as acidic fibroblast growth factor, and FGF2 is also known as basic fibroblast growth factor. Members...
25 KB (3,124 words) - 21:38, 18 August 2024
responding to this growth factor, TrkB (pronounced "Track B") and the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). It may...
46 KB (5,344 words) - 17:28, 12 October 2024
Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has...
17 KB (1,708 words) - 22:30, 15 October 2024
Insulin-like growth factor 2 has been shown to interact with IGFBP3 and transferrin. Insulin-like growth factor 2 receptor Insulin-like growth factor II IRES...
15 KB (1,932 words) - 08:59, 2 November 2024
MST1 (redirect from Hepatocyte growth factor-like protein)
Macrophage-stimulating protein (MSP), also known as hepatocyte growth factor-like protein (HLP, HGFL, or HGFLP), is a protein that in humans is encoded...
7 KB (901 words) - 22:17, 3 March 2023
specific fibroblast growth factor receptor (FGFR) proteins, themselves a family of closely related molecules. Fibroblast growth factor protein was first...
22 KB (2,698 words) - 17:05, 16 July 2024
and ketogenesis. FGF21 stimulates phosphorylation of fibroblast growth factor receptor substrate 2 and ERK1/2 in the liver. Acute FGF21 treatment induced...
24 KB (3,038 words) - 18:36, 14 July 2024
Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays a significant...
24 KB (2,882 words) - 16:31, 25 October 2024