α-Catenin (alpha-catenin) functions as the primary protein link between cadherins and the actin cytoskeleton. It has been reported that the actin binding...
21 KB (2,888 words) - 12:36, 25 September 2024
identified became known as α-catenin and β-catenin. α-Catenin can bind to β-catenin and can also bind filamentous actin (F-actin). β-Catenin binds directly to...
29 KB (3,618 words) - 03:22, 11 November 2024
Catenin beta-1, also known as β-catenin (beta-catenin), is a protein that in humans is encoded by the CTNNB1 gene. β-Catenin is a dual function protein...
107 KB (12,347 words) - 05:01, 2 November 2024
the actomyosin cytoskeleton. p120-catenin controls E-cadherin membrane localization, while β-catenin and α-catenin provide the link that connect AJs to...
54 KB (6,380 words) - 07:38, 8 October 2024
junctions. α-catenin and β-catenin are integral components of adherens junctions, which bind together to produce cadherin-α-catenin-β-catenin complexes...
24 KB (3,025 words) - 00:37, 28 November 2024
intracellular catenin proteins, specifically the three different subtypes, α-catenins, β-catenins, and p120ctn family catenins. β-catenins and p120ctns...
21 KB (2,558 words) - 08:17, 1 August 2024
Catenin alpha-3, also known as αT-catenin, is a α-catenin protein that in humans is encoded by the CTNNA3 gene. Janssens B, Goossens S, Staes K, Gilbert...
1 KB (84 words) - 06:36, 16 April 2024
Catenin alpha-2, also known as αN-catenin, is a type of α-catenin protein that in humans is encoded by the CTNNA2 gene. Claverie JM, Hardelin JP, Legouis...
1 KB (84 words) - 06:37, 16 April 2024
of the cell. This allows for homophilic cell–cell adhesion. The β-catenin–α-catenin linked complex at the adherens junctions allows for the formation...
20 KB (2,277 words) - 03:36, 21 November 2024
catenin) binds the juxtamembrane region of the cadherin. γ-catenin or gamma-catenin (plakoglobin) binds the catenin-binding region of the cadherin. α-catenin...
5 KB (505 words) - 05:55, 18 April 2024
by followers ensures long-range coordination of cell migration through α-catenin mechanoperception". Developmental Cell. 57 (12): 1529–1544.e5. doi:10...
18 KB (2,187 words) - 19:01, 15 January 2024
CL, Nelson WJ, Smith SJ (Dec 1996). "Quantitative analysis of cadherin-catenin-actin reorganization during development of cell-cell adhesion". The Journal...
153 KB (18,311 words) - 13:09, 4 January 2025
its sequence is 20%–30% similar to α-catenin, which serves a similar function. Binding alternately to talin or α-actinin, vinculin's shape and, as a...
24 KB (2,985 words) - 15:31, 6 November 2024
HTR2B a serotonin receptor gene. CTNNA2 encodes for a brain-expressed α-catenin that has been associated with Excitement-Seeking in a genome-wide association...
143 KB (15,735 words) - 10:23, 2 December 2024
forming an adhesion complex. This adhesion complex is formed by β-catenin and α-catenin, and p120CAS is essential for its stabilization and regulation....
99 KB (11,432 words) - 04:27, 2 November 2024
Toksoz D (2004). "Distinct Activities of the α-Catenin Family, α-Catulin and α-Catenin, on β-Catenin-Mediated Signaling". Mol. Cell. Biol. 24 (6): 2410–22...
4 KB (522 words) - 01:31, 28 March 2022
αE-catenin, also known as Catenin alpha-1 is a protein that in humans is encoded by the CTNNA1 gene. αE-catenin is highly expressed in cardiac muscle...
23 KB (2,782 words) - 21:55, 15 April 2024
PTPRK (section Cadherin-catenin signaling)
PTPkappa interacts by co-immunoprecipitation with E-cadherin, α-catenin and β-catenin in pancreatic acinar cells prior to the dissolution of adherens...
34 KB (4,376 words) - 18:07, 10 June 2024
nomenclature is the gap junction protein system, where connexins are sorted by their α (GJA) and β (GJB) forms, with additional connexins grouped into the C, D and...
26 KB (2,569 words) - 17:52, 24 September 2024
T, Weiss TM, Stanley CB, Heller WT, Martel A, et al. (August 2018). "α-Catenin Structure and Nanoscale Dynamics in Solution and in Complex with F-Actin"...
11 KB (1,154 words) - 18:03, 29 November 2023
integral part of the Wnt canonical pathway (β-catenin dependent) and non-canonical pathway (β-catenin-independent). In either of these, DVL acts downstream...
12 KB (1,387 words) - 18:30, 20 July 2024
cadherin/catenin complex in the cytoskeleton. As EpCAM expression increases, the total amount of α-catenin decreases, whereas cellular β-catenin levels...
20 KB (2,451 words) - 18:22, 29 November 2024
usually composed of α-, β-, and γ-catenins, bind to the cytoplasmic portion of the cadherin. Regulatory proteins include p-120 catenin, α {\displaystyle \alpha...
32 KB (3,594 words) - 21:23, 2 October 2024
PMID 20457762. Takeichi, Masatoshi (2018-10-01). "Multiple functions of α-catenin beyond cell adhesion regulation". Current Opinion in Cell Biology. Cell...
9 KB (961 words) - 02:47, 17 September 2024
Examples of proteins that contain armadillo repeats include β-catenin, Sarm1 (SARM1), α-importin, plakoglobin, adenomatous polyposis coli (APC), and many...
5 KB (571 words) - 20:27, 2 December 2023
regulation of cell adhesion and actin cytoskeleton via E-cadherin and α-catenin". Proc. Natl. Acad. Sci. U.S.A. 103 (28): 10672–7. Bibcode:2006PNAS..10310672H...
6 KB (715 words) - 06:13, 3 April 2024
been suggested that O-GlcNAc plays a role in the interaction of α-catenin and β-catenin. Co-translational O-GlcNAc has been identified on Sp1 and Nup62...
129 KB (14,328 words) - 07:57, 30 December 2024
transitions by regulating the cell adhesion proteins E-cadherin, α-catenin and γ-catenin expression in epithelial cells. Studies have shown that in highly...
15 KB (1,845 words) - 11:24, 31 October 2024
up of polymerized α- and β-tubulin dimers. The inner space of the hollow microtubule cylinders is referred to as the lumen. The α and β-tubulin subunits...
62 KB (7,838 words) - 13:27, 31 December 2024