17α-Hydroxyprogesterone (17α-OHP), also known as 17-OH progesterone (17-OHP), or hydroxyprogesterone (OHP), is an endogenous progestogen steroid hormone...
14 KB (1,126 words) - 10:08, 7 July 2024
treatment of preterm birth in 2011 until the FDA banned 17α-OHPC in 2023. The use of hydroxyprogesterone caproate in pregnancy to prevent preterm birth in women...
121 KB (12,026 words) - 08:48, 2 November 2024
Medroxyprogesterone (redirect from 6α-Methyl-17α-hydroxyprogesterone)
contraction of 6α-methyl-17α-hydroxyprogesterone. It is closely related to medrogestone as well as other unesterified 17α-hydroxyprogesterone derivatives such as...
7 KB (482 words) - 04:13, 23 October 2024
Medroxyprogesterone acetate (redirect from 6α-methyl-17α-hydroxyprogesterone acetate)
6α-methyl-17α-acetoxyprogesterone or as 6α-methyl-17α-acetoxypregn-4-ene-3,20-dione, and its generic name is a contraction of 6α-methyl-17α-hydroxyprogesterone...
177 KB (18,939 words) - 06:32, 22 December 2024
has more than 50-fold higher affinity for the PR isoforms than 17α-hydroxyprogesterone, a little less than half the affinity of progesterone, and slightly...
26 KB (3,336 words) - 21:46, 22 August 2024
Progestogen ester (redirect from 17α-hydroxyprogesterone esters)
include the 17α-hydroxyprogesterone derivatives medroxyprogesterone acetate, megestrol acetate, cyproterone acetate, and hydroxyprogesterone caproate, the...
22 KB (2,387 words) - 00:35, 9 December 2023
progestogen esters, with the exception of esters of 17α-hydroxyprogesterone like hydroxyprogesterone caproate, are esters of progestins (synthetic progestogens)...
9 KB (834 words) - 17:43, 20 February 2024
also known as 9α-fluoro-16α-hydroxyprednisolone 16α,17α-acetonide or as 9α-fluoro-11β,16α-17α,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal...
16 KB (1,220 words) - 14:16, 5 September 2024
by adding prefixes only rather than suffixes, e.g., the steroid 17α-hydroxyprogesterone has a hydroxy group (-OH) at position 17 of the steroid nucleus...
84 KB (8,686 words) - 07:48, 29 December 2024
being the testosterone derivatives and, to a lesser extent, the 17α-hydroxyprogesterone derivatives medroxyprogesterone acetate and megestrol acetate....
176 KB (18,555 words) - 06:07, 16 November 2024
hypoaldosteronism) Elevated 17α-hydroxyprogesterone Classic 21-hydroxylase deficiency typically causes 17α-hydroxyprogesterone blood levels >242 nmol/L.[medical...
43 KB (4,344 words) - 07:26, 16 December 2024
hydroxyprogesterone enanthate (OHPE), as well as 17α-hydroxyprogesterone heptanoate or 17α-hydroxypregn-4-ene-3,20-dione 17α-heptanoate, is a synthetic pregnane steroid...
17 KB (1,285 words) - 16:49, 8 June 2024
hydroxyl group has been substituted at the C17α position (as in 17α-hydroxyprogesterone), the acetyl group at the C17β position has been cyclized with...
182 KB (17,411 words) - 06:58, 5 January 2025
hydroxylated via 17α-hydroxylase (CYP17A1) and 21-hydroxylase (CYP21A2) into 17α-hydroxyprogesterone and 11-deoxycorticosterone (21-hydroxyprogesterone), respectively...
124 KB (11,584 words) - 01:50, 4 January 2025
testosterone. DHT may also be synthesized from progesterone and 17α-hydroxyprogesterone via the androgen backdoor pathway in the absence of testosterone...
67 KB (6,840 words) - 13:39, 4 January 2025
metabolite of progesterone that is formed in lower amounts than 17α-hydroxyprogesterone (17α-OHP). It occurs in micromolar concentrations and its physiological...
4 KB (341 words) - 20:53, 22 December 2023
CYP17A1 (redirect from 17α-hydroxylase)
(C17) of the steroid D ring (the 17α-hydroxylase activity, EC 1.14.14.19), or acts upon 17α-hydroxyprogesterone and 17α-hydroxypregnenolone to split the...
25 KB (2,704 words) - 11:13, 30 December 2024
are used in medicine. Major examples of progestins include the 17α-hydroxyprogesterone derivative medroxyprogesterone acetate and the 19-nortestosterone...
16 KB (1,567 words) - 01:04, 8 October 2024
other 17α-hydroxyprogesterone derivatives such as acetomepregenol, anagestone acetate, chlormadinone acetate, cyproterone acetate, hydroxyprogesterone caproate...
108 KB (11,654 words) - 08:32, 16 May 2024
Metribolone (redirect from 17α-Methyltrenbolone)
is a synthetic and orally active anabolic–androgenic steroid (AAS) and a 17α-alkylated nandrolone (19-nortestosterone) derivative which was never marketed...
17 KB (1,337 words) - 06:11, 15 December 2023
5α-Pregnan-17α-ol-3,20-dione, also known as 17α-hydroxy-dihydroprogesterone (17-OH-DHP) is an endogenous steroid, a metabolite of 17α-hydroxyprogesterone. 5α-Pregnan-17α-ol-3...
11 KB (1,041 words) - 11:22, 1 January 2025
Gynaecology and Obstetrics. de Gruyter. p. 49. ISBN 9783110006148. 17α-Hydroxyprogesterone caproate is a depot progestogen which is entirely free of side...
61 KB (6,716 words) - 21:19, 6 January 2025
Dienogest has antiovulatory potency that is similar to that of 17α-hydroxyprogesterone derivatives like cyproterone acetate but endometrial potency that...
61 KB (5,612 words) - 07:18, 6 November 2024
Progesterone → Allopregnanedione → Allopregnanolone 17α-Hydroxypregnenolone → 17α-Hydroxyprogesterone Androgens Dehydroepiandrosterone → Androstenedione...
7 KB (649 words) - 20:31, 24 December 2024
17α-hydroxyprogesterone. It is structurally related to other 17α-hydroxyprogesterone derivatives such as chlormadinone acetate, hydroxyprogesterone caproate...
142 KB (14,112 words) - 11:33, 8 December 2024
Retroprogesterone derivatives: Dydrogesterone Trengestone 17α-Hydroxyprogesterone (and closely related) derivatives: 17α-Hydroxylated: Acetomepregenol (mepregenol diacetate)...
23 KB (1,906 words) - 14:31, 24 November 2024
[1] 11β-Hydroxyprogesterone (21-deoxycorticosterone) = 11β-hydroxypregn-4-ene-3,20-dione 11β,17α,21-Trihydroxypregnenolone = 3β,11β,17α...
11 KB (1,237 words) - 00:17, 3 December 2023
progestogen, retroprogesterone is not medically used. Note that 17α-hydroxyprogesterone is inactive as a progestogen and is not used medically. The 19-norprogesterone...
13 KB (270 words) - 12:57, 12 October 2022
Estradiol valerate/hydroxyprogesterone caproate (EV/OHPC), sold under the brand names Gravibinon and Injectable No. 1 (or Chinese Injectable No. 1) among...
19 KB (1,697 words) - 20:00, 16 March 2024
intermediate product within the androgen backdoor pathway in which 17α-hydroxyprogesterone (17-OHP) is 5α-reduced and finally converted to 5α-dihydrotestosterone...
14 KB (1,217 words) - 08:11, 20 August 2024