in humans is encoded by the ABCG2 gene. ABCG2 has also been designated as CDw338 (cluster of differentiation w338). ABCG2 is a translocation protein used...

negative blood is most common in people of Japanese heritage. The gene ABCG2, located on chromosome 4q22.1, encodes an ATP-binding cassette transporter...

yeast. The ABCG2 gene was discovered in cell lines selected for high level resistance for mitoxantrone and no expression of ABCB1 or ABCC1. ABCG2 can export...

amide hydrolase (FAAH) in vivo. Firefly luciferin is a substrate of the ABCG2 transporter and has been used as part of a bioluminescence imaging high...

of CYP3A4, CYP2C19, CYP2C9, UDP-glucuronosyltransferase, P-glycoprotein, ABCG2, or OATP1B1 may be reduced to varying extents. In terms of effects of other...

ATP-binding cassette (ABC) transporter proteins: ABCB1, ABCC1, ABCC2, and ABCG2. Irinotecan clearance is mainly biliary (66%) and estimated 12–21 L/h/m2...

transporter 1), OCT2, OATP1B3 (SLCO1B3), P-gp (P-glycoprotein), or BCRP (ABCG2). Multidrug resistance-associated protein 2 (MRP2)-vesicular accumulation...

"Membrane topology of the human breast cancer resistance protein (BCRP/ABCG2) determined by epitope insertion and immunofluorescence". Biochemistry....

MRX may refer to: The ABCG2 gene MRX complex, DNA damage repair complex in yeast The Magnetic Reconnection eXperiment led by DoE's Princeton Plasma Physics...

about 60% of variability in uric acid level. The SLC2A9, SLC22A12, and ABCG2 genes have been found to be commonly associated with gout and variations...

other cytochrome P450 enzymes. It is transported by P-glycoprotein and ABCG2 and also inhibits these carrier proteins in vitro. It also inhibits the...

number of genes, linked to serum urate, have so far been identified: SLC2A9; ABCG2; SLC17A1; SLC22A11; SLC22A12; SLC16A9; GCKR; LRRC16A; and PDZK1. GLUT9,...

theoretical interaction is with drugs with affinity to the transporter protein ABCG2 (also known as BCRP), such as pitavastatin, pravastatin, ciprofloxacin,...

cancer-related molecules such as DNA, enzymes (GPX4, kinases, etc.) and proteins (ABCG2/BRCP1, etc.), they are also discussed as potential anticancer agents. The...

(ABC) transporter, mitochondrial porphyrin transporter. 2q36 033 Junior JR ABCG2. Multi-drug transporter protein.[citation needed] 4q22 034 Vel Vel Human...

include OATP1B1 (SLCO1B1) and breast cancer resistance protein (BCRP) (ABCG2). Pharmacodynamics refers to the impact a medication has on the body, or...

gene expression. ABCG2 is a protein that is responsible for multidrug resistance in cancer chemotherapy. Increased expression of ABCG2 is found in different...

from decreased deoxycytidine kinase activity in vitro. ABC transporter ABCG2 promotes export of clofarabine-5´-monophosphate and thus limits the cytotoxic...

Sissung TM, Burger H, Nooter K, Soepenberg O, et al. (July 2004). "Effect of ABCG2 genotype and mRNA expression on the bioavailability of topotecan". Journal...

inhibitor and a substrate of the transporter proteins P-glycoprotein (Pgp), ABCG2, OATP1B1 and OATP1B3. It is partly degraded by the liver enzymes CYP2B6...

Locher, Kaspar P. (2017). "Structure of the human multidrug transporter ABCG2". Nature. 546 (7659): 504–509. Bibcode:2017Natur.546..504T. doi:10.1038/nature22345...

antineoplastic drugs. The study showed that apatinib reverses the ABCB1- and ABCG2-mediated multidrug resistance by inhibiting those functions and increasing...

proteins ABCG2 (breast cancer resistance protein, BCRP) and P-glycoprotein (P-gp), which has been shown to increase plasma concentrations of the ABCG2 substrate...

NCR3 or NKp30. Protein that in humans is encoded by the NCR3 gene. CD338 ABCG2 (ATP-binding cassette sub-family G member 2) or BCRP (Breast Cancer Resistance...

ABCF2 HGNC:71 Q9UG63 70 ABCF3 HGNC:72 Q9NUQ8 71 ABCG1 HGNC:73 P45844 72 ABCG2 HGNC:74 Q9UNQ0 73 ABCG4 HGNC:13884 Q9H172 74 ABCG5 HGNC:13886 Q9H222 75...

and weight standards Asset-backed commercial paper An alternate name for ABCG2, the human gene ATP-binding cassette, sub-family G (WHITE), member 2 As...

Haimeur A, Conseil G, Deeley RG, Cole SP (2004). "The MRP-related and BCRP/ABCG2 multidrug resistance proteins: biology, substrate specificity and regulation"...

"Avapritinib: A Selective Inhibitor of KIT and PDGFRα that Reverses ABCB1 and ABCG2-Mediated Multidrug Resistance in Cancer Cell Lines". Mol. Pharm. 16 (7):...

2009, Coresh was the co-author of "Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout" which received the...

substrate of P-glycoprotein and ABCG2 transporters. It acts as an inhibitor for both transporters, especially for ABCG2. Therefore, drugs that are substrates...