5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular...
65 KB (7,149 words) - 04:45, 26 August 2024
5'-AMP-activated protein kinase (AMP-activated protein kinase). Protein kinase A, more precisely known as adenosine 3',5'-monophosphate (cyclic AMP)-dependent...
27 KB (2,665 words) - 17:03, 6 April 2024
Mitogen-activated protein kinase kinase (also known as MAP2K, MEK, MAPKK) is a dual-specificity kinase enzyme which phosphorylates mitogen-activated protein kinase...
3 KB (296 words) - 17:06, 14 September 2023
5'-AMP-activated protein kinase catalytic subunit alpha-1 is an enzyme that in humans is encoded by the PRKAA1 gene. The protein encoded by this gene...
10 KB (1,257 words) - 05:06, 26 August 2024
A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses...
46 KB (5,492 words) - 14:52, 20 August 2024
Adenosine monophosphate (redirect from 5'-AMP)
eukaryotic cell enzyme 5' adenosine monophosphate-activated protein kinase, or AMPK, utilizes AMP for homeostatic energy processes during times of high...
14 KB (1,255 words) - 07:33, 5 March 2024
molecules, including integrin-linked kinase (ILK) and mitogen-activated protein kinase-activated protein kinase-2 (MAPKAPK2) can also serve as PDK2. Phosphorylation...
35 KB (3,831 words) - 18:08, 20 August 2024
(July 2007). "Metformin and phenformin activate AMP-activated protein kinase in the heart by increasing cytosolic AMP concentration". American Journal of...
150 KB (14,340 words) - 06:10, 14 September 2024
transcriptional activation domain. They belong to the mitogen-activated protein kinase family, and are responsive to stress stimuli, such as cytokines...
14 KB (1,626 words) - 20:50, 30 May 2024
PKCs are activated through the same signal transduction pathway as phospholipase C. On the other hand, atypical (a)PKCs (including protein kinase Mζ and...
27 KB (2,716 words) - 12:30, 12 September 2024
p38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines...
14 KB (1,385 words) - 10:32, 28 April 2024
Rho-associated protein kinase (ROCK) is a kinase belonging to the AGC (PKA/ PKG/PKC) family of serine-threonine specific protein kinases. It is involved...
19 KB (2,170 words) - 06:41, 27 May 2024
decrease in activity of the enzyme is caused by AMP-activated protein kinase, which responds to an increase in AMP concentration, and also to leptin. Since the...
34 KB (4,113 words) - 16:29, 29 July 2024
[citation needed] In the MAPK/ERK pathway, Ras activates c-Raf, followed by mitogen-activated protein kinase kinase (abbreviated as MKK, MEK, or MAP2K) and then...
11 KB (1,128 words) - 19:03, 18 September 2023
The IκB kinase enzyme complex is part of the upstream NF-κB signal transduction cascade. The IκBα (inhibitor of nuclear factor kappa B) protein inactivates...
14 KB (1,447 words) - 09:31, 22 December 2023
CAMK (redirect from Calcium/calmodulin-dependent protein kinase II)
an abbreviation for the Ca2+/calmodulin-dependent protein kinase class of enzymes. CAMKs are activated by increases in the concentration of intracellular...
8 KB (886 words) - 12:46, 31 January 2024
Ca2+ /calmodulin-dependent protein kinase II (CaM kinase II or CaMKII) is a serine/threonine-specific protein kinase that is regulated by the Ca2+ /calmodulin...
29 KB (3,458 words) - 16:39, 17 March 2024
Ribosomal protein S6 kinase beta-1 (S6K1), also known as p70S6 kinase (p70S6K, p70-S6K), is an enzyme (specifically, a protein kinase) that in humans...
18 KB (2,129 words) - 11:19, 3 September 2024
domain by protein kinases. Cyclic AMP-dependent protein kinases (protein kinase A) are activated by the signal chain coming from the G protein (that was...
82 KB (9,384 words) - 16:34, 5 September 2024
increase in the substrate demand. This leads to an activation of AMP-activated protein kinase (AMPK) as the AMP concentration rises in intracellular fluids and...
12 KB (1,520 words) - 20:36, 31 August 2024
A serine/threonine protein kinase (EC 2.7.11.-) is a kinase enzyme, in particular a protein kinase, that phosphorylates the OH group of the amino-acid...
14 KB (1,210 words) - 13:35, 14 June 2024
kinase (rsk) is a family of protein kinases involved in signal transduction. There are two subfamilies of rsk, p90rsk, also known as MAPK-activated protein...
5 KB (510 words) - 17:10, 16 September 2021
GK. In contrast, phosphorylation of GKRP by AMP-activated protein kinase, induced by elevated levels of AMP, reduces its capacity to inactivate GK. A presence...
15 KB (1,696 words) - 00:07, 20 December 2023
gene. The DMPK gene product is a Ser/Thr protein kinase homologous to the MRCK p21-activated kinases and Rho kinase family. Data obtained by using antibodies...
19 KB (2,426 words) - 16:47, 30 March 2024
Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases involved in the regulation of the cell cycle and its progression...
35 KB (3,829 words) - 14:24, 17 June 2024
MTORC1 (category Protein pages needing a picture)
Arbiser JL, Bonner MY, et al. (February 2012). "Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and...
69 KB (7,803 words) - 11:01, 11 April 2024
cGMP-dependent protein kinase or protein kinase G (PKG) is a serine/threonine-specific protein kinase that is activated by cGMP. It phosphorylates a number...
8 KB (825 words) - 21:37, 20 April 2023
metformin and a potent oxidative phosphorylation inhibitor and AMP-activated protein kinase activating biguanide. Certain types of cancer cells requires oxidative...
8 KB (607 words) - 16:20, 17 February 2024
the mitogen-activated protein kinase (MAPK) cascade. Activation of RAF kinases requires interaction with RAS-GTPases. The three RAF kinase family members...
5 KB (556 words) - 08:06, 3 June 2024
5'-AMP-activated protein kinase subunit gamma-2 is an enzyme that in humans is encoded by the PRKAG2 gene. AMP-activated protein kinase (AMPK) is a heterotrimeric...
9 KB (1,084 words) - 03:22, 25 December 2023