acid receptor (also known as AMPA receptor, AMPAR, or quisqualate receptor) is an ionotropic transmembrane receptor for glutamate (iGluR)...
60 KB (7,024 words) - 22:23, 19 October 2024
acid, better known as AMPA, is a compound that is a specific agonist for the AMPA receptor, where it mimics the effects of the neurotransmitter...
4 KB (274 words) - 23:44, 16 December 2024
protein receptors such as NMDA and AMPA receptors. Post-synaptic AMPA receptor: AMPA Receptors are trans-membrane protein ionotropic receptors that open...
16 KB (2,011 words) - 14:35, 3 December 2023
Ligand-gated ion channel (redirect from Ionotropic receptor)
acid receptor (also known as AMPA receptor, or quisqualate receptor) is a non-NMDA-type ionotropic transmembrane receptor for glutamate that...
29 KB (2,617 words) - 22:05, 20 December 2024
Ampakine (redirect from AMPA receptor agonist)
Ampakines or AMPAkines are a subgroup of AMPA receptor positive allosteric modulators with a benzamide or closely related chemical structure. They are...
9 KB (928 words) - 16:55, 9 June 2024
non-NMDA-type receptor, along with the AMPA receptor. KARs are less understood than AMPA and NMDA receptors, the other ionotropic glutamate receptors. Postsynaptic...
11 KB (1,263 words) - 21:34, 11 June 2024
GRIA2 (redirect from Glutamate receptor 2)
Glutamate ionotropic receptor AMPA type subunit 2 (Glutamate receptor 2, or GluR-2) is a protein that in humans is encoded by the GRIA2 (or GLUR2) gene...
24 KB (3,304 words) - 04:20, 27 August 2024
AMPA receptor positive allosteric modulators are positive allosteric modulators (PAMs) of the AMPA receptor (AMPR), a type of ionotropic glutamate receptor...
12 KB (1,260 words) - 22:48, 19 October 2024
Willardiine (section AMPA receptors in disease)
impermeable in over 99% of AMPA receptors. Like AMPA receptors, kainate receptors are tetrameric, transmembrane, ionotropic glutamate receptors on glutamatergic...
44 KB (4,913 words) - 12:01, 11 January 2025
NMDA-type glutamate receptors but no AMPA-type glutamate receptors. These synapses are named "silent" because normal AMPA receptor-mediated signaling is...
13 KB (1,613 words) - 20:11, 12 November 2023
in excessive stimulation of receptors. For example, when glutamate receptors such as the NMDA receptor or AMPA receptor encounter excessive levels of...
25 KB (2,792 words) - 14:34, 11 December 2024
Perampanel (category AMPA receptor antagonists)
antiepileptic drug in the class of selective non-competitive antagonist of AMPA receptors. The drug label has a black box warning that the drug may cause serious...
17 KB (1,511 words) - 03:06, 12 January 2025
Osavampator (category AMPA receptor positive allosteric modulators)
modulator (PAM) of the AMPA receptor. Osavampator and other AMPA PAMs potentiate the effects of agonists at the main site of the AMPA receptor by slowing the...
9 KB (766 words) - 05:13, 5 September 2024
Barbiturate (category AMPA receptor antagonists)
this receptor. In addition to this GABAergic effect, barbiturates also block AMPA and kainate receptors, subtypes of ionotropic glutamate receptor. Glutamate...
45 KB (4,742 words) - 21:43, 31 December 2024
the glutamate receptor-interacting protein (GRIP) family have been shown to interact with GluR2, a common subunit in the AMPA receptor. This subunit also...
18 KB (2,168 words) - 17:38, 3 December 2023
Ibotenic acid (category AMPA receptor agonists)
metabotropic glutamate receptors. It is inactive at group III mGluRs. Ibotenic acid also acts as a weak agonist of the AMPA and kainate receptors. In addition,...
16 KB (1,473 words) - 02:32, 12 January 2025
Caramboxin (category AMPA receptor agonists)
Caramboxin stimulates the glutamate receptors in neurons, being an agonist of both NMDA and AMPA glutamatergic ionotropic receptors with potent excitatory, convulsant...
7 KB (586 words) - 11:00, 21 January 2025
activation of the AMPA receptor. Overall signal can be increased by preventing the desensitization of a receptor. Desensitization prevents a receptor from activating...
19 KB (2,293 words) - 20:29, 8 July 2024
glutamate receptors, such as NMDA (N-methyl-D-aspartate), AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), and kainate receptors, have distinct...
63 KB (6,876 words) - 07:52, 2 November 2024
via long-term potentiation. While AMPA receptor activation leads to depolarization via sodium influx, NMDA receptor activation by rapid successive firing...
46 KB (5,344 words) - 15:43, 27 November 2024
Piracetam (category AMPA receptor positive allosteric modulators)
sedative or stimulant. Piracetam is a positive allosteric modulator of the AMPA receptor, although this action is very weak and its clinical effects may not...
24 KB (2,346 words) - 14:32, 12 January 2025
neurotransmitter receptors, are highly mobile in the plasma membrane due to lateral diffusion. Fast movements of AMPA-type glutamate receptors (AMPARs) are...
27 KB (3,147 words) - 12:02, 12 January 2025
JNCL could be due to overactive AMPA receptors in the cerebellum. To test this hypothesis, researchers administered AMPA antagonist drugs into affected...
33 KB (3,612 words) - 09:35, 18 December 2024
is one of three types of ionotropic glutamate receptors, the other two being AMPA and kainate receptors. Depending on its subunit composition, its ligands...
107 KB (12,054 words) - 08:06, 9 January 2025
GRIA4 (category Ionotropic glutamate receptors)
neurotransmitters receptors pre-mRNa are substrates for ADARs. This includes 5 subunits of the glutamate receptor ionotropic AMPA glutamate receptor subunits (Glur2...
15 KB (2,008 words) - 02:06, 27 January 2024
phosphorylate existing AMPA receptors to increase their activity. Second, they mediate or modulate the insertion of additional AMPA receptors into the postsynaptic...
61 KB (7,328 words) - 18:22, 12 August 2024
and sequence similarity: AMPA receptors, kainate receptors, NMDA receptors and delta receptors (see below). AMPA receptors are the main charge carriers...
5 KB (433 words) - 06:16, 15 October 2023
kainate receptors, are similar in many respects to AMPA receptors, but much less abundant. Many synapses use multiple types of glutamate receptors. AMPA receptors...
20 KB (2,177 words) - 10:19, 11 December 2024
that increases synaptic capacity for AMPA receptors. This is what leads to a long-term increase in AMPA receptors and thus synaptic strength and plasticity...
30 KB (3,613 words) - 17:57, 25 November 2024
Theanine (category AMPA receptor antagonists)
in the micromolar range, including the AMPA and kainate receptors and, to a lesser extent, the NMDA receptor. It acts as an antagonist of the former...
22 KB (2,172 words) - 04:07, 20 January 2025