Adenine phosphoribosyltransferase (APRTase) is an enzyme encoded by the APRT gene, found in humans on chromosome 16. It is part of the Type I PRTase family...
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Adenine phosphoribosyltransferase deficiency is a rare autosomal recessive metabolic disorder caused by mutations of the APRT gene. Adenine phosphoribosyltransferase...
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A phosphoribosyltransferase is a type of transferase enzyme. Types include: Adenine phosphoribosyltransferase Hypoxanthine-guanine phosphoribosyltransferase...
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Nicotinamide phosphoribosyltransferase (NAmPRTase or NAMPT), formerly known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin for its extracellular...
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are two types of phosphoribosyltransferases: adenine phosphoribosyltransferase (APRT) and hypoxanthine-guanine phosphoribosyltransferase (HGPRT). HGPRT...
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Nicotinamide adenine dinucleotide (NAD) is a coenzyme central to metabolism. Found in all living cells, NAD is called a dinucleotide because it consists...
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amidotransferase; adenine phosphoribosyltransferase. It is also used to treat kidney stones caused by deficient activity of adenine phosphoribosyltransferase. Allopurinol...
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Thiemann, Otavio H. (2008). "Structural Complexes of Human Adenine Phosphoribosyltransferase Reveal Novel Features of the APRT Catalytic Mechanism". Journal...
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mononucleotide-dimethylbenzimidazole phosphoribosyltransferase, nicotinate ribonucleotide:benzimidazole (adenine) phosphoribosyltransferase, nicotinate-nucleotide:...
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excreted in the urine because of a deficiency in the adenine salvage enzyme adenine phosphoribosyltransferase. The defect is inherited as an autosomal recessive...
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Urlaub, G; Chasin, L (1979). "DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells". Proceedings of the National Academy...
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Purine metabolism (redirect from Adenine pathway)
nucleotides. The enzyme adenine phosphoribosyltransferase (APRT) salvages adenine. The enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT) salvages...
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often produce stones composed of xanthine. People affected by adenine phosphoribosyltransferase deficiency may produce 2,8-dihydroxyadenine stones, alkaptonurics...
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transfer of a pentose. Examples include: adenine phosphoribosyltransferase hypoxanthine-guanine phosphoribosyltransferase pertussis toxin poly ADP ribose polymerase...
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thumb syndrome recessive form Adducted thumbs Dundar type Adenine phosphoribosyltransferase deficiency Adenocarcinoid tumor Adenocarcinoma of esophagus...
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In enzymology, a xanthine phosphoribosyltransferase (EC 2.4.2.22) is an enzyme that catalyzes the chemical reaction XMP + diphosphate ⇌ {\displaystyle...
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cells are known to become resistant to DAP by losing their adenine phosphoribosyltransferase (APRT) function, a process shared with E. coli. DAP derivatives...
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(i.e. animals, yeast, plants, diatoms, brown algae) APT (adenine phosphoribosyltransferase) genes. Therefore, knockouts or mutants for APT, which are...
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Transphosphoribosidase may refer to: Adenine phosphoribosyltransferase, an enzyme Hypoxanthine phosphoribosyltransferase This set index page lists enzyme...
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APRT may refer to: Adenine phosphoribosyltransferase, an enzyme Adenine phosphoribosyltransferase deficiency, a genetic and metabolic disorder This disambiguation...
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Lesch–Nyhan syndrome (redirect from Complete hypoxanthine-guanine phosphoribosyltransferase deficiency)
disorder caused by a deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT). This deficiency occurs due to mutations in the HPRT1...
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nucleotide salvage. For example, adenine + PRPP --> AMP + PPi. This reaction requires the enzyme adenine phosphoribosyltransferase. Free guanine is salvaged...
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Hypoxanthine-guanine phosphoribosyltransferase converts hypoxanthine into IMP in nucleotide salvage. Hypoxanthine is also a spontaneous deamination product of adenine. Because...
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and a form of vitamin B3. It functions as a precursor to nicotinamide adenine dinucleotide, or NAD+, through a two-step and a three-step pathway. While...
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consisting of one to three phosphates. The four nucleobases in DNA are guanine, adenine, cytosine, and thymine; in RNA, uracil is used in place of thymine. Nucleotides...
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661–671. A Saccharomyces cerevisiae gene encoding a potential adenine phosphoribosyltransferase Yuryev A, and Corden JL. Yeast 1994;10 (5): 659–662. Determination...
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the nucleic acid RNA. The others are adenine (A), cytosine (C), and guanine (G). In RNA, uracil binds to adenine via two hydrogen bonds. In DNA, the uracil...
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phosphotransacetylase, adenylosuccinate synthase, adenine phosphoribosyltransferases, and guanine phosphoribosyltransferases. The human subjects experienced increases...
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2.4.2.7: adenine phosphoribosyltransferase EC 2.4.2.8: hypoxanthine phosphoribosyltransferase EC 2.4.2.9: uracil phosphoribosyltransferase EC 2.4.2.10:...
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nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme responsible for the transformation of nicotinamide into nicotinamide adenine dinucleotide...
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