• Thumbnail for Adenine phosphoribosyltransferase
    Adenine phosphoribosyltransferase (APRTase) is an enzyme encoded by the APRT gene, found in humans on chromosome 16. It is part of the Type I PRTase family...
    21 KB (2,410 words) - 19:32, 2 September 2023
  • Thumbnail for Adenine phosphoribosyltransferase deficiency
    Adenine phosphoribosyltransferase deficiency is a rare autosomal recessive metabolic disorder caused by mutations of the APRT gene. Adenine phosphoribosyltransferase...
    24 KB (2,087 words) - 07:42, 21 October 2024
  • A phosphoribosyltransferase is a type of transferase enzyme. Types include: Adenine phosphoribosyltransferase Hypoxanthine-guanine phosphoribosyltransferase...
    463 bytes (24 words) - 10:24, 7 April 2024
  • Thumbnail for Nicotinamide phosphoribosyltransferase
    Nicotinamide phosphoribosyltransferase (NAmPRTase or NAMPT), formerly known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin for its extracellular...
    28 KB (3,227 words) - 12:56, 7 July 2024
  • are two types of phosphoribosyltransferases: adenine phosphoribosyltransferase (APRT) and hypoxanthine-guanine phosphoribosyltransferase (HGPRT). HGPRT...
    7 KB (736 words) - 10:22, 12 August 2024
  • Thumbnail for Nicotinamide adenine dinucleotide
    Nicotinamide adenine dinucleotide (NAD) is a coenzyme central to metabolism. Found in all living cells, NAD is called a dinucleotide because it consists...
    79 KB (9,020 words) - 21:04, 28 October 2024
  • Thumbnail for Allopurinol
    amidotransferase; adenine phosphoribosyltransferase. It is also used to treat kidney stones caused by deficient activity of adenine phosphoribosyltransferase. Allopurinol...
    31 KB (2,798 words) - 23:42, 18 October 2024
  • Thumbnail for Phosphoribosyl pyrophosphate
    Thiemann, Otavio H. (2008). "Structural Complexes of Human Adenine Phosphoribosyltransferase Reveal Novel Features of the APRT Catalytic Mechanism". Journal...
    11 KB (921 words) - 11:15, 20 October 2023
  • Thumbnail for Nicotinate-nucleotide—dimethylbenzimidazole phosphoribosyltransferase
    mononucleotide-dimethylbenzimidazole phosphoribosyltransferase, nicotinate ribonucleotide:benzimidazole (adenine) phosphoribosyltransferase, nicotinate-nucleotide:...
    9 KB (928 words) - 17:58, 23 January 2024
  • Thumbnail for 2,8-Dihydroxyadenine
    excreted in the urine because of a deficiency in the adenine salvage enzyme adenine phosphoribosyltransferase. The defect is inherited as an autosomal recessive...
    4 KB (282 words) - 09:21, 24 January 2024
  • Thumbnail for Richard Axel
    Urlaub, G; Chasin, L (1979). "DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells". Proceedings of the National Academy...
    15 KB (1,386 words) - 05:40, 8 October 2024
  • nucleotides. The enzyme adenine phosphoribosyltransferase (APRT) salvages adenine. The enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT) salvages...
    14 KB (1,640 words) - 17:31, 21 November 2024
  • Thumbnail for Kidney stone disease
    often produce stones composed of xanthine. People affected by adenine phosphoribosyltransferase deficiency may produce 2,8-dihydroxyadenine stones, alkaptonurics...
    132 KB (13,797 words) - 23:46, 18 October 2024
  • transfer of a pentose. Examples include: adenine phosphoribosyltransferase hypoxanthine-guanine phosphoribosyltransferase pertussis toxin poly ADP ribose polymerase...
    575 bytes (53 words) - 17:59, 23 January 2024
  • thumb syndrome recessive form Adducted thumbs Dundar type Adenine phosphoribosyltransferase deficiency Adenocarcinoid tumor Adenocarcinoma of esophagus...
    24 KB (1,972 words) - 21:28, 16 August 2024
  • In enzymology, a xanthine phosphoribosyltransferase (EC 2.4.2.22) is an enzyme that catalyzes the chemical reaction XMP + diphosphate ⇌ {\displaystyle...
    2 KB (203 words) - 16:29, 22 September 2024
  • Thumbnail for 2,6-Diaminopurine
    cells are known to become resistant to DAP by losing their adenine phosphoribosyltransferase (APRT) function, a process shared with E. coli. DAP derivatives...
    14 KB (1,394 words) - 13:56, 4 August 2024
  • Thumbnail for 2-Fluoroadenine
    (i.e. animals, yeast, plants, diatoms, brown algae) APT (adenine phosphoribosyltransferase) genes. Therefore, knockouts or mutants for APT, which are...
    8 KB (683 words) - 13:39, 25 April 2024
  • Transphosphoribosidase may refer to: Adenine phosphoribosyltransferase, an enzyme Hypoxanthine phosphoribosyltransferase This set index page lists enzyme...
    449 bytes (43 words) - 14:59, 5 February 2015
  • APRT may refer to: Adenine phosphoribosyltransferase, an enzyme Adenine phosphoribosyltransferase deficiency, a genetic and metabolic disorder This disambiguation...
    174 bytes (47 words) - 17:20, 27 December 2019
  • Thumbnail for Lesch–Nyhan syndrome
    disorder caused by a deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT). This deficiency occurs due to mutations in the HPRT1...
    38 KB (4,775 words) - 16:51, 5 September 2024
  • Thumbnail for Nucleic acid metabolism
    nucleotide salvage. For example, adenine + PRPP --> AMP + PPi. This reaction requires the enzyme adenine phosphoribosyltransferase. Free guanine is salvaged...
    13 KB (1,457 words) - 22:06, 24 December 2023
  • Thumbnail for Hypoxanthine
    Hypoxanthine-guanine phosphoribosyltransferase converts hypoxanthine into IMP in nucleotide salvage. Hypoxanthine is also a spontaneous deamination product of adenine. Because...
    6 KB (509 words) - 19:39, 27 August 2024
  • Thumbnail for Nicotinamide riboside
    and a form of vitamin B3. It functions as a precursor to nicotinamide adenine dinucleotide, or NAD+, through a two-step and a three-step pathway. While...
    21 KB (1,932 words) - 05:33, 14 October 2024
  • Thumbnail for Nucleotide
    consisting of one to three phosphates. The four nucleobases in DNA are guanine, adenine, cytosine, and thymine; in RNA, uracil is used in place of thymine. Nucleotides...
    32 KB (3,305 words) - 17:28, 19 November 2024
  • 661–671. A Saccharomyces cerevisiae gene encoding a potential adenine phosphoribosyltransferase Yuryev A, and Corden JL. Yeast 1994;10 (5): 659–662. Determination...
    15 KB (2,036 words) - 01:48, 9 September 2022
  • Thumbnail for Uracil
    the nucleic acid RNA. The others are adenine (A), cytosine (C), and guanine (G). In RNA, uracil binds to adenine via two hydrogen bonds. In DNA, the uracil...
    29 KB (2,943 words) - 16:12, 20 November 2024
  • phosphotransacetylase, adenylosuccinate synthase, adenine phosphoribosyltransferases, and guanine phosphoribosyltransferases. The human subjects experienced increases...
    17 KB (1,992 words) - 20:32, 29 February 2024
  • 2.4.2.7: adenine phosphoribosyltransferase EC 2.4.2.8: hypoxanthine phosphoribosyltransferase EC 2.4.2.9: uracil phosphoribosyltransferase EC 2.4.2.10:...
    215 KB (21,664 words) - 23:41, 8 May 2024
  • Thumbnail for P7C3
    nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme responsible for the transformation of nicotinamide into nicotinamide adenine dinucleotide...
    4 KB (313 words) - 18:12, 8 April 2023