• Thumbnail for Adenosine A2B receptor
    The adenosine A2B receptor, also known as ADORA2B, is a G-protein coupled adenosine receptor, and also denotes the human adenosine A2b receptor gene which...
    21 KB (2,125 words) - 15:36, 22 September 2024
  • Thumbnail for Adenosine receptor
    four known types of adenosine receptors in humans: A1, A2A, A2B and A3; each is encoded by a different gene. The adenosine receptors are commonly known...
    25 KB (2,072 words) - 00:37, 4 October 2024
  • Thumbnail for Adenosine A2A receptor
    The adenosine A2A receptor, also known as ADORA2A, is an adenosine receptor, and also denotes the human gene encoding it. This protein is a member of...
    46 KB (5,133 words) - 08:40, 23 September 2024
  • Thumbnail for Adenosine
    Cellular signaling by adenosine occurs through four known adenosine receptor subtypes (A1, A2A, A2B, and A3). Extracellular adenosine concentrations from...
    32 KB (3,346 words) - 08:35, 21 September 2024
  • A2B may refer to: A2B, Adenosine A2B receptor A2B Australia, a taxi operator A2B Bicycles, an electric bicycle company A2B-online, an intermodal trailer...
    446 bytes (92 words) - 18:15, 15 November 2023
  • subtypes of adenosine A2 receptors are known. Both are G protein-coupled adenosine receptors: Adenosine A2A receptor Adenosine A2B receptor This disambiguation...
    340 bytes (54 words) - 19:36, 24 December 2009
  • An adenosine receptor antagonist is a drug which acts as an antagonist of one or more of the adenosine receptors. The best known are xanthines and their...
    5 KB (492 words) - 03:33, 27 August 2024
  • Thumbnail for Adenosine A1 receptor
    The adenosine A1 receptor (A1AR) is one member of the adenosine receptor group of G protein-coupled receptors with adenosine as endogenous ligand. A1 receptors...
    19 KB (1,973 words) - 04:09, 22 September 2024
  • Thumbnail for Biginelli reaction
    Biginelli reaction have been investigated as potential selective Adenosine A2b receptor antagonists. Including highly selective tricyclic compounds. The...
    10 KB (1,044 words) - 22:55, 1 August 2024
  • Thumbnail for Adenosine A3 receptor
    The adenosine A3 receptor, also known as ADORA3, is an adenosine receptor, but also denotes the human gene encoding it. Adenosine A3 receptors are G protein-coupled...
    20 KB (2,122 words) - 03:18, 17 October 2024
  • Thumbnail for G protein-coupled receptor
    protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G...
    82 KB (9,384 words) - 16:34, 5 September 2024
  • Thumbnail for ISAM-140
    a selective non-xanthinic adenosine A2B receptor antagonist. Discovered in 2016, it has a Ki of 3.49 nM on the A2B receptor and >1000-fold selectivity...
    3 KB (190 words) - 03:24, 27 August 2024
  • Thumbnail for Netrin receptor DCC
    "Netrin-1-mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor". Nature. 407 (6805): 747–50. Bibcode:2000Natur.407..747C. doi:10...
    39 KB (5,119 words) - 20:51, 23 September 2024
  • Thumbnail for Cell surface receptor
    Cell surface receptors (membrane receptors, transmembrane receptors) are receptors that are embedded in the plasma membrane of cells. They act in cell...
    21 KB (2,456 words) - 22:14, 21 November 2023
  • Thumbnail for BAY 60–6583
    BAY 60–6583 (category Adenosine receptor agonists)
    BAY 60–6583 is a selective adenosine A2B receptor agonist. It has been shown to provide protection from ischemia (lack of oxygen due to blocked blood supply)...
    5 KB (334 words) - 11:27, 21 October 2024
  • Thumbnail for Tissue-type plasminogen activator
    "Inhibition of tPA-induced hemorrhagic transformation involves adenosine A2b receptor activation after cerebral ischemia". Neurobiol Dis. 108: 173–182...
    28 KB (3,063 words) - 04:57, 17 August 2024
  • Thumbnail for P2Y receptor
    P2Y receptors are a family of purinergic G protein-coupled receptors, stimulated by nucleotides such as adenosine triphosphate, adenosine diphosphate...
    19 KB (1,870 words) - 05:36, 3 June 2024
  • Thumbnail for Dopamine receptor
    D1–adenosine A1 D2–adenosine A2A D2–ghrelin receptor D2sh–TAAR1 (an autoreceptor heteromer) D4–adrenoceptor α1B D4–adrenoceptor β1 Dopamine receptor D1...
    50 KB (5,330 words) - 16:58, 20 November 2024
  • Thumbnail for GABA receptor
    of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled...
    35 KB (3,892 words) - 05:20, 16 May 2024
  • Thumbnail for Lu AA41063
    Lu AA41063 (category Adenosine receptor antagonists)
    the adenosine A2A receptor, 410 nM for the adenosine A1 receptor (69-fold lower than for the A2A receptor), 260 nM for the adenosine A2B receptor (44-fold...
    8 KB (731 words) - 08:47, 26 September 2024
  • Thumbnail for Olfactory receptor
    Olfactory receptors (ORs), also known as odorant receptors, are chemoreceptors expressed in the cell membranes of olfactory receptor neurons and are responsible...
    36 KB (4,353 words) - 15:38, 20 September 2024
  • Thumbnail for Opioid receptor
    Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands. The endogenous opioids are dynorphins, enkephalins, endorphins...
    40 KB (4,427 words) - 12:37, 12 January 2024
  • Thumbnail for D9-Caffeine
    antagonist at adenosine receptors. d9-Caffeine was assessed for human adenosine receptor antagonism at the four receptor subtypes: A1, A2A, A2B, and A3, and...
    9 KB (873 words) - 11:42, 13 November 2024
  • Thumbnail for Adrenergic receptor
    The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline)...
    33 KB (2,982 words) - 11:42, 7 August 2024
  • lower affinity to A2A and A2B receptors causing dilation of efferent arterioles. The binding of adenosine to the A1 receptor causes a complex signal cascade...
    21 KB (2,605 words) - 07:10, 21 June 2024
  • Thumbnail for Purinergic signalling
    receptors on the neutrophil, and the affinity of these receptors for adenosine. Micromolar concentrations of adenosine activate A2A and A2B receptors...
    54 KB (5,956 words) - 10:13, 12 August 2024
  • Cholecystokinin receptors or CCK receptors are a group of G-protein coupled receptors which bind the peptide hormones cholecystokinin (CCK) and gastrin...
    4 KB (229 words) - 19:29, 28 January 2023
  • Thumbnail for Interleukin 8
    lung tissue. Some benzodiazepines have inhibitory effects on the adenosine A2B receptor mediated secretion of interleukin-8 in human mast cells. In a 2013...
    24 KB (2,881 words) - 19:11, 20 November 2024
  • Thumbnail for Alpha-2 adrenergic receptor
    The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein. It consists...
    25 KB (2,231 words) - 17:54, 18 September 2024
  • Thumbnail for Glucagon-like peptide-1 receptor
    The glucagon-like peptide-1 receptor (GLP1R) is a G protein-coupled receptor (GPCR) found on beta cells of the pancreas and on neurons of the brain. It...
    33 KB (4,119 words) - 09:50, 28 October 2024