Adenylate cyclase toxin is a virulence factor produced by some members of the genus Bordetella. Together with the pertussis toxin it is the most important...

Adenylate cyclase (EC 4.6.1.1, also commonly known as adenyl cyclase and adenylyl cyclase, abbreviated AC) is an enzyme with systematic name ATP diphosphate-lyase...

activity of pertussis toxin". Microbiol Sci. 5 (9): 285–7. PMID 2908558. Carbonetti NH (2010). "Pertussis toxin and adenylate cyclase toxin: key virulence factors...

most important of the regulated toxins is adenylate cyclase toxin, which aids in the evasion of innate immunity. The toxin is delivered to phagocytic immune...

Extracellular adenylate cyclase is an adenylate cyclase produced by Bordetella pertussis. Kessin RH, Franke J (April 1986). "Secreted adenylate cyclase of Bordetella...

Adenylate cyclase toxin (CyaA) is released from bacterium Bordetella pertussis by the T1SS (Type 1 secretion system) and released in the host’s respiratory...

or whooping cough. Its virulence factors include pertussis toxin, adenylate cyclase toxin, filamentous haemagglutinin, pertactin, fimbria, and tracheal...

changes consistent with apoptosis. The C-terminal domain of the adenylate cyclase toxin (ACT or CyaA; TC# 1.C.11.1.4) of Bordetella pertussis forms a small...

A activates the G protein which activates adenylate cyclase. The three-dimensional structure of the toxin was determined using X-ray crystallography...

A toxin is a naturally occurring poison produced by metabolic activities of living cells or organisms. They occur especially as proteins, often conjugated...

paralysis. The toxin causes the disease botulism. The toxin is also used commercially for medical and cosmetic purposes. Botulinum toxin is an acetylcholine...

activation of adenylate cyclase stimulatory G (Gs)-protein-coupled receptors. Adenylate cyclase is inhibited by agonists of adenylate cyclase inhibitory...

Retrieved 24 August 2012. Carbonetti NH (March 2010). "Pertussis toxin and adenylate cyclase toxin: key virulence factors of Bordetella pertussis and cell biology...

"A" toxins in B. anthracis: the edema factor (EF) and the lethal factor (LF). LF is a Zn metalloprotease that cleaves MAPKK; EF is a adenylate cyclase that...

Tetanus toxin (TeNT) is an extremely potent neurotoxin produced by the vegetative cell of Clostridium tetani in anaerobic conditions, causing tetanus...

damage-inducing processes. EF acts as a Ca2+ and calmodulin dependent adenylate cyclase that greatly increases the level of cAMP in the cell. This increase...

Shiga toxins are a family of related toxins with two major groups, Stx1 and Stx2, expressed by genes considered to be part of the genome of lambdoid prophages...

spore-forming, motile bacterium with the ability to produce botulinum toxin, which is a neurotoxin. C. botulinum is a diverse group of pathogenic bacteria...

improve the environment for further fungal proliferation. The production of toxins depends on the surrounding intrinsic and extrinsic environments and these...

Neurotoxins are toxins that are destructive to nerve tissue (causing neurotoxicity). Neurotoxins are an extensive class of exogenous chemical neurological...

that occurs during gas gangrene. Gas gangrene is caused by alpha toxin, or α-toxin, that embeds itself into the plasma membrane of cells and disrupts...

(1982). "Requirements for cholera toxin-dependent ADP-ribosylation of the purified regulatory component of adenylate cyclase". The Journal of Biological Chemistry...

Anthrax toxin is composed of three domains: protective antigen (PA), edema factor (EF), and lethal factor (LF). EF is an adenylate cyclase that targets...

surface of muscle cells and cause depolarisation → the toxin prevents muscle contraction. These toxins may cause the heart to beat irregularly or stop beating...

intracellular toxins do not directly inhibit protein synthesis. For example, Cholera toxin ADP-ribosylates, thereby activating tissue adenylate cyclase to increase...

the active state and it will continuously stimulate adenylate cyclase. The sustained adenylate cyclase activity will lead to a sustained increase of cAMP...

the collective name of a subgroup of at least nine related cyclic peptide toxins found in three genera of deadly poisonous mushrooms (Amanita, Galerina and...

Diphtheria toxin is an exotoxin secreted mainly by Corynebacterium diphtheriae but also by Corynebacterium ulcerans and Corynebacterium pseudotuberculosis...

RY-sin) is a lectin (a carbohydrate-binding protein) and a highly potent toxin produced in the seeds of the castor oil plant, Ricinus communis. The median...

PMC 3760862. PMID 24019885. Carbonetti, N. H. (2010). "Pertussis toxin and adenylate cyclase toxin: Key virulence factors of Bordetella pertussis and cell biology...