An aldose is a monosaccharide (a simple sugar) with a carbon backbone chain with a carbonyl group on the endmost carbon atom, making it an aldehyde, and...
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Aldose reductase inhibitors are a class of drugs being studied as a way to prevent eye and nerve damage in people with diabetes. Their target, aldose...
6 KB (578 words) - 09:59, 12 June 2024
In enzymology, aldose reductase (or aldehyde reductase) (EC 1.1.1.21) is a cytosolic NADPH-dependent oxidoreductase that catalyzes the reduction of a variety...
17 KB (1,881 words) - 07:19, 3 June 2024
Ekenstein transformation is the base or acid catalyzed transformation of an aldose into the ketose isomer or vice versa, with a tautomeric enediol as reaction...
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Isomerase (redirect from Aldose-ketose isomerases)
oxidoreductase. The overall reaction involves the opening of the ring to form an aldose via acid/base catalysis and the subsequent formation of a cis-endiol intermediate...
37 KB (3,590 words) - 06:06, 12 July 2024
enzymology, an aldose-1-phosphate nucleotidyltransferase (EC 2.7.7.37) is an enzyme that catalyzes the chemical reaction NDP + alpha-D-aldose 1-phosphate...
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In enzymology, an aldose 1-epimerase (EC 5.1.3.3) is an enzyme that catalyzes the chemical reaction alpha-D-glucose ⇌ {\displaystyle \rightleftharpoons...
3 KB (254 words) - 13:02, 26 August 2023
In enzymology, an aldose 1-dehydrogenase (EC 1.1.1.121) is an enzyme that catalyzes the chemical reaction D-aldose + NAD+ ⇌ {\displaystyle \rightleftharpoons...
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Polyol pathway (redirect from Sorbitol-aldose reductase pathway)
which is subsequently oxidized to fructose. It is also called the sorbitol-aldose reductase pathway. The pathway is implicated in diabetic complications,...
7 KB (816 words) - 01:38, 30 November 2023
and is technically an aldehyde. In that case, the compound is termed an aldose. Otherwise, the molecule has a ketone group, a carbonyl −(C=O)− between...
15 KB (2,051 words) - 07:39, 25 July 2024
Xylose isomerase (redirect from D-xylose aldose-ketose-isomerase)
isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The isomerase has now been observed in nearly a hundred species...
21 KB (2,269 words) - 07:40, 9 August 2024
In enzymology, an aldose-6-phosphate reductase (NADPH) (EC 1.1.1.200) is an enzyme that catalyzes the chemical reaction D-sorbitol 6-phosphate + NADP+...
2 KB (180 words) - 13:03, 26 August 2023
enzymology, an aldose-1-phosphate adenylyltransferase (EC 2.7.7.36) is an enzyme that catalyzes the chemical reaction ADP + alpha-D-aldose 1-phosphate ⇌...
2 KB (179 words) - 13:03, 26 August 2023
enzymology, a D-threo-aldose 1-dehydrogenase (EC 1.1.1.122) is an enzyme that catalyzes the chemical reaction a D-threo-aldose + NAD+ ⇌ {\displaystyle...
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between aldose and ketose sugars. If the sugar contains a ketone group, it is a ketose. If a sugar contains an aldehyde group, it is an aldose. This test...
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from formaldehyde. The term formose is a portmanteau of formaldehyde and aldose. The reaction is catalyzed by a base and a divalent metal such as calcium...
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pathway is the reduction of aldoses, types of sugars including galactose, to sugar alcohols. Recent data suggests that aldose reductase is the enzyme responsible...
19 KB (1,858 words) - 10:28, 12 August 2024
Reducing sugar (section Aldoses and ketoses)
groups: the aldoses, which have an aldehyde group, and the ketoses, which have a ketone group. Ketoses must first tautomerize to aldoses before they can...
14 KB (1,690 words) - 21:19, 11 July 2024
the aldehyde group (−CH=O) located at the initial end (position 1) of an aldose is oxidized. Ulosonic acids, in which the hydroxymethyl group (−CH2OH) at...
3 KB (241 words) - 16:13, 24 March 2024
GPI uses to interconvert glucose 6-phosphate and fructose 6-phosphate (aldose to ketose) consists of three major steps: opening the glucose ring, isomerizing...
28 KB (3,057 words) - 00:34, 10 March 2024
Epalrestat (category Aldose reductase inhibitors)
Epalrestat is a carboxylic acid derivative and a noncompetitive and reversible aldose reductase inhibitor used for the treatment of diabetic neuropathy, which...
8 KB (754 words) - 14:10, 5 June 2024
converted into a hydroxyl group. The reaction requires NADH and is catalyzed by aldose reductase. Glucose reduction is the first step of the polyol pathway of...
21 KB (2,054 words) - 22:25, 13 August 2024
Triose-phosphate isomerase (TPI or TIM) is an enzyme (EC 5.3.1.1) that catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone...
11 KB (1,178 words) - 16:06, 26 August 2023
formyl group (–CH=O), the sugar is called an aldohexose, a special case of aldose. Otherwise, if the carbonyl position is 2 or 3, the sugar is a derivative...
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HO2C(CHOH)nCH2OH. They are obtained by oxidizing the aldehyde (-CHO group) of an aldose to form a carboxylic acid (-COOH group). Aldonic acids are generally found...
8 KB (779 words) - 21:53, 26 June 2024
In enzymology, an aldose beta-D-fructosyltransferase (EC 2.4.1.162) is an enzyme that catalyzes the chemical reaction alpha-D-aldosyl1 beta-D-fructoside...
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Mannose isomerase (redirect from D-mannose aldose-ketose-isomerase)
intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is D-mannose aldose-ketose-isomerase. Other names in common...
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L-arabinose isomerase (redirect from L-arabinose aldose-ketose-isomerase)
oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is L-arabinose aldose-ketose-isomerase. This enzyme participates...
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D-lyxose ketol-isomerase (redirect from D-lyxose aldose-ketose-isomerase)
intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is D-lyxose aldose-ketose-isomerase. Other names in common...
2 KB (136 words) - 13:43, 26 August 2023
Hydroxypyruvate isomerase (redirect from Hydroxypyruvate aldose-ketose-isomerase)
oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is hydroxypyruvate aldose-ketose-isomerase. This enzyme participates...
1 KB (115 words) - 14:31, 26 August 2023