An aldose is a monosaccharide (a simple sugar) with a carbon backbone chain with a carbonyl group on the endmost carbon atom, making it an aldehyde, and...

Aldose reductase inhibitors are a class of drugs being studied as a way to prevent eye and nerve damage in people with diabetes. Their target, aldose...

In enzymology, aldose reductase (or aldehyde reductase) (EC 1.1.1.21) is a cytosolic NADPH-dependent oxidoreductase that catalyzes the reduction of a variety...

Ekenstein transformation is the base or acid catalyzed transformation of an aldose into the ketose isomer or vice versa, with a tautomeric enediol as reaction...

oxidoreductase. The overall reaction involves the opening of the ring to form an aldose via acid/base catalysis and the subsequent formation of a cis-endiol intermediate...

enzymology, an aldose-1-phosphate nucleotidyltransferase (EC 2.7.7.37) is an enzyme that catalyzes the chemical reaction NDP + alpha-D-aldose 1-phosphate...

In enzymology, an aldose 1-epimerase (EC 5.1.3.3) is an enzyme that catalyzes the chemical reaction alpha-D-glucose ⇌ {\displaystyle \rightleftharpoons...

In enzymology, an aldose 1-dehydrogenase (EC 1.1.1.121) is an enzyme that catalyzes the chemical reaction D-aldose + NAD+ ⇌ {\displaystyle \rightleftharpoons...

which is subsequently oxidized to fructose. It is also called the sorbitol-aldose reductase pathway. The pathway is implicated in diabetic complications,...

and is technically an aldehyde. In that case, the compound is termed an aldose. Otherwise, the molecule has a ketone group, a carbonyl −(C=O)− between...

isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The isomerase has now been observed in nearly a hundred species...

In enzymology, an aldose-6-phosphate reductase (NADPH) (EC 1.1.1.200) is an enzyme that catalyzes the chemical reaction D-sorbitol 6-phosphate + NADP+...

enzymology, an aldose-1-phosphate adenylyltransferase (EC 2.7.7.36) is an enzyme that catalyzes the chemical reaction ADP + alpha-D-aldose 1-phosphate ⇌...

enzymology, a D-threo-aldose 1-dehydrogenase (EC 1.1.1.122) is an enzyme that catalyzes the chemical reaction a D-threo-aldose + NAD+ ⇌ {\displaystyle...

between aldose and ketose sugars. If the sugar contains a ketone group, it is a ketose. If a sugar contains an aldehyde group, it is an aldose. This test...

from formaldehyde. The term formose is a portmanteau of formaldehyde and aldose. The reaction is catalyzed by a base and a divalent metal such as calcium...

pathway is the reduction of aldoses, types of sugars including galactose, to sugar alcohols. Recent data suggests that aldose reductase is the enzyme responsible...

groups: the aldoses, which have an aldehyde group, and the ketoses, which have a ketone group. Ketoses must first tautomerize to aldoses before they can...

the aldehyde group (−CH=O) located at the initial end (position 1) of an aldose is oxidized. Ulosonic acids, in which the hydroxymethyl group (−CH2OH) at...

GPI uses to interconvert glucose 6-phosphate and fructose 6-phosphate (aldose to ketose) consists of three major steps: opening the glucose ring, isomerizing...

Epalrestat is a carboxylic acid derivative and a noncompetitive and reversible aldose reductase inhibitor used for the treatment of diabetic neuropathy, which...

converted into a hydroxyl group. The reaction requires NADH and is catalyzed by aldose reductase. Glucose reduction is the first step of the polyol pathway of...

Triose-phosphate isomerase (TPI or TIM) is an enzyme (EC 5.3.1.1) that catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone...

formyl group (–CH=O), the sugar is called an aldohexose, a special case of aldose. Otherwise, if the carbonyl position is 2 or 3, the sugar is a derivative...

HO2C(CHOH)nCH2OH. They are obtained by oxidizing the aldehyde (-CHO group) of an aldose to form a carboxylic acid (-COOH group). Aldonic acids are generally found...

In enzymology, an aldose beta-D-fructosyltransferase (EC 2.4.1.162) is an enzyme that catalyzes the chemical reaction alpha-D-aldosyl1 beta-D-fructoside...

intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is D-mannose aldose-ketose-isomerase. Other names in common...

oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is L-arabinose aldose-ketose-isomerase. This enzyme participates...

intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is D-lyxose aldose-ketose-isomerase. Other names in common...

oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is hydroxypyruvate aldose-ketose-isomerase. This enzyme participates...