Allele age (or mutation age) is the amount of time elapsed since an allele first appeared due to mutation. Estimating the time at which a certain allele...

prevalent, if a male is producing offspring with a more diverse range of alleles, offspring will be more likely to withstand mortality from disease and...

color-variant of the above patterns, having pheomelanin (O allele) instead of eumelanin (o allele). Though generally a mix of orange and white, the ratio...

used to refer to the alleles or variants an individual carries in a particular gene or genetic location. The number of alleles an individual can have...

or brown pigment). This gene is located on the X chromosome. The orange allele is O, and non-orange is o. Males can typically only be orange or non-orange...

the age of the mutation to be 2250 years (900–4700, 95% confidence interval). A third hypothesis relies on the north-to-south gradient of allele frequency...

recessive manner. It is caused by the presence of mutations in both copies (alleles) of the gene encoding the cystic fibrosis transmembrane conductance regulator...

of other ethnicities are also known to harbor the mutation. The young allele age may be a consequence of past selection. One hypothesis as to why the otherwise...

Paleo-Indians had both variants of the EDAR gene, the derived G-allele and the ancestral A-allele. When they[who?] tested ancient DNA remains found in the Americas...

Among different Latin heritages, frequency of the dementia-predisposing ε4 allele of apoE4 gene was highest for Caribbean Latinos (Cubans, Dominicans, Puerto...

a different allele of the same gene that produces the short curly hair of the Devon Rex (termed the "re" allele), with the Sphynx's allele being incompletely...

probability of fixing beneficial alleles and also slightly decreases the probability of fixing deleterious alleles in a population. Inbreeding can result...

of two E4 alleles have between 10 and 30 times the risk of developing AD by 75 years of age, as compared to those not carrying any E4 alleles. This may...

one allele dominates the instructions from another, it is called the dominant allele, and the allele that is overridden is called the recessive allele. In...

rs7412, lead to three major APO-E alleles with different associated risks for development of Alzheimer's disease and age at onset of the disease. Single...

are called alleles. DNA sequences can change through mutations, producing new alleles. If a mutation occurs within a gene, the new allele may affect the...

lactase-activity allele (the ancestral allele) from their parents, who may be homozygous or at least heterozygous for the allele. Only one high-activity allele is required...

"Whole-Genome-Sequence-Based Haplotypes Reveal Single Origin of the Sickle Allele during the Holocene Wet Phase". American Journal of Human Genetics. 102...

Dobney, Keith; Leonard, Jennifer A.; Larson, Greger (2016). "A novel MC1R allele for black coat colour reveals the Polynesian ancestry and hybridization...

gray alleles, will always produce gray foals. Gray is common in many breeds. Today, about one horse in 10 carries the mutation for graying with age. The...

When the new allele is created, a heterozygote containing the newly created allele as well as the original will express the new allele; genetically this...

of a particular gene (allele) in a given population to a situation where only one of the alleles remains. That is, the allele becomes fixed. In the absence...

first reviewed in 1981. Natural selection can support lethal and harmful alleles, if their effects are felt after reproduction. The geneticist J. B. S....

or New Stone Age. Single nucleotide polymorphisms (SNP, pronounced 'snip'), or mutations of a single genetic code "letter" in an allele that spread across...

occurs when the black gene has two recessive alleles but the dilution gene has at least one dominant allele (i.e., bbDD, bbDd). The blue Dobermann has the...

penetrance allele (RPA) may cause symptoms, usually later in the adult life. The maximum risk is 60% that a person with an RPA will be symptomatic at age 65,...

incidence of death due to cardiovascular disease in old age. It also linked specific alleles to a combination of higher fertility, stronger inflammatory...

incomplete dominant allele with a distinct dosage effect. The DNA sequence responsible for the cream colors is the cream allele, which is at a specific...

It has been hypothesized that natural selection favored this allele during the last ice age in a population of people living in isolation in Beringia, as...

were dark skinned while similarly aged hunter gatherers in Sweden were light skinned (having predominately derived alleles of SLC24A5, SLC45A2 and also HERC2/OCA2)...