δ-Aminolevulinic acid (also dALA, δ-ALA, 5ALA or 5-aminolevulinic acid), an endogenous non-proteinogenic amino acid, is the first compound in the porphyrin...
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Aminolevulinic acid synthase (ALA synthase, ALAS, or delta-aminolevulinic acid synthase) is an enzyme (EC 2.3.1.37) that catalyzes the synthesis of δ-aminolevulinic...
10 KB (1,308 words) - 19:05, 13 February 2024
Aminolevulinic acid dehydratase (porphobilinogen synthase, or ALA dehydratase, or aminolevulinate dehydratase) is an enzyme (EC 4.2.1.24) that in humans...
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Aminolevulinic acid dehydratase deficiency porphyria (also known as Doss porphyria, plumboporphyria, or ADP) is an extremely rare autosomal recessive...
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complementary therapy for obesity. β-lipoic acid is a thiosulfinate of α-lipoic acid Aminolevulinic acid "Lipoic Acid". Pubmed. NCBI. Retrieved October 18,...
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the third. Examples include β-alanine, GABA, and δ-aminolevulinic acid. β-alanine: an amino acid produced by aspartate 1-decarboxylase and a precursor...
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include acute intermittent porphyria (AIP), variegate porphyria (VP), aminolevulinic acid dehydratase deficiency porphyria (ALAD), hereditary coproporphyria...
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formation of δ-aminolevulinic acid (δ-ALA, 5-ALA or dALA) by the reaction of the amino acid glycine with succinyl-CoA from the citric acid cycle. In plants...
25 KB (2,304 words) - 18:35, 7 October 2024
Tretinoin (redirect from All-trans retinoic acid)
Tretinoin, also known as all-trans retinoic acid (ATRA), is a medication used for the treatment of acne and acute promyelocytic leukemia. For acne, it...
31 KB (2,908 words) - 06:38, 22 September 2024
Vitamin B6 (section Amino acid metabolism)
chlorophyll depends on aminolevulinic acid synthase, a PLP-dependent enzyme that uses succinyl-CoA and glycine to generate aminolevulinic acid, a chlorophyll...
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succinylacetone has been shown to decrease heme concentrations by inhibiting δ-aminolevulinic acid in murine erythroleukemia cells. The primary structure of heme-sequestering...
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Glycine (redirect from Aminoethanoic acid)
starting with GG, namely GGU, GGC, GGA and GGG. In higher eukaryotes, δ-aminolevulinic acid, the key precursor to porphyrins, is biosynthesized from glycine...
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Root Nodules: I. On the Role of Bacteroid delta-Aminolevulinic Acid Synthase and delta-Aminolevulinic Acid Dehydrase in the Synthesis of the Heme of Leghemoglobin"...
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additives. The largest application of levulinic acid is its use in the production of aminolevulinic acid, a biodegradable herbicide used in South Asia....
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increased if the surgery is guided by a fluorescent dye known as 5-aminolevulinic acid. GBM cells are widely infiltrative through the brain at diagnosis...
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to treat the lesions include ALA-PDT (photodynamic therapy with aminolevulinic acid), applying 5-FU, imiquimod, and retinoids by mouth. The lesions tend...
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initiated by the synthesis of δ-aminolevulinic acid (dALA or δALA) from the amino acid glycine and succinyl-CoA from the citric acid cycle (Krebs cycle). The...
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pharmaceutical company. Hexaminolevulinate is a structural analogue to 5-aminolevulinic acid (a precursor to the porphyrin ring of heme), and is internalized...
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Many steps are involved in converting aminolevulinic acid via uroporphyrinogen III and adenosylcobyric acid to the final forms in which it is used by...
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Photodynamic therapy (section 5-Aminolaevulinic acid)
They divide into porphyrins, chlorins and dyes. Examples include aminolevulinic acid (ALA), Silicon Phthalocyanine Pc 4, m-tetrahydroxyphenylchlorin (mTHPC)...
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givosiran received EMA approval. Givosiran is an siRNA that breaks down aminolevulinic acid synthase 1 (ALAS1) mRNA in the liver. Breaking down ALAS1 mRNA prevents...
140 KB (15,409 words) - 08:23, 28 October 2024
precursors, such as aminolevulinic acid, which may be directly or indirectly harmful to neurons. Elevation of aminolevulinic acid results in lead poisoning...
198 KB (21,311 words) - 22:25, 15 November 2024
H3 receptor agonist Aminolevulinic acid/sodium ferrous citrate (5-ALA-SFC, 5-ALA/SFX; sodium ferrous citrate/aminolevulinic acid; SPP-003) – erythropoiesis...
38 KB (3,022 words) - 17:10, 10 November 2024
Acne (section Azelaic acid)
following the application of a sensitizing substance to the skin such as aminolevulinic acid or methyl aminolevulinate, the treatment is referred to as photodynamic...
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interfere with, such as the antifolates that interfere with the use of folic acid; thus, competitive inhibition can occur, and the presence of antimetabolites...
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of colorectal cancer. It is made up of the following drugs: FOL – folinic acid (leucovorin), a vitamin B derivative with multiple applications, which in...
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of δ-aminolevulinic acid, which can cause the acute symptoms in an attack of the acute porphyrias. Acute intermittent porphyria Aminolevulinic acid Inborn...
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precursor. In angiosperms, this regulation is achieved at the step of aminolevulinic acid (ALA), one of the intermediate compounds in the biosynthesis pathway...
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known to substitute for zinc in a number of enzymes, including δ-aminolevulinic acid dehydratase (porphobilinogen synthase) in the haem biosynthetic pathway...
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glutamyl-tRNA reductase, an enzyme needed for the formation of 5-Aminolevulinic acid which is a precursor of heme and chlorophyll. Yellowing (Chlorosis)...
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