• Thumbnail for Aminolevulinic acid
    δ-Aminolevulinic acid (also dALA, δ-ALA, 5ALA or 5-aminolevulinic acid), an endogenous non-proteinogenic amino acid, is the first compound in the porphyrin...
    17 KB (1,747 words) - 19:53, 17 March 2024
  • Thumbnail for Aminolevulinic acid synthase
    Aminolevulinic acid synthase (ALA synthase, ALAS, or delta-aminolevulinic acid synthase) is an enzyme (EC 2.3.1.37) that catalyzes the synthesis of δ-aminolevulinic...
    10 KB (1,308 words) - 19:05, 13 February 2024
  • Thumbnail for Delta-aminolevulinic acid dehydratase
    Aminolevulinic acid dehydratase (porphobilinogen synthase, or ALA dehydratase, or aminolevulinate dehydratase) is an enzyme (EC 4.2.1.24) that in humans...
    17 KB (1,918 words) - 18:27, 25 July 2024
  • Thumbnail for Aminolevulinic acid dehydratase deficiency porphyria
    Aminolevulinic acid dehydratase deficiency porphyria (also known as Doss porphyria, plumboporphyria, or ADP) is an extremely rare autosomal recessive...
    10 KB (976 words) - 14:24, 19 October 2024
  • Thumbnail for Lipoic acid
    complementary therapy for obesity. β-lipoic acid is a thiosulfinate of α-lipoic acid Aminolevulinic acid "Lipoic Acid". Pubmed. NCBI. Retrieved October 18,...
    48 KB (4,967 words) - 06:52, 17 October 2024
  • Thumbnail for Non-proteinogenic amino acids
    the third. Examples include β-alanine, GABA, and δ-aminolevulinic acid. β-alanine: an amino acid produced by aspartate 1-decarboxylase and a precursor...
    27 KB (2,864 words) - 19:08, 10 October 2024
  • Thumbnail for Porphyria
    include acute intermittent porphyria (AIP), variegate porphyria (VP), aminolevulinic acid dehydratase deficiency porphyria (ALAD), hereditary coproporphyria...
    64 KB (6,617 words) - 00:41, 19 October 2024
  • Thumbnail for Porphyrin
    formation of δ-aminolevulinic acid (δ-ALA, 5-ALA or dALA) by the reaction of the amino acid glycine with succinyl-CoA from the citric acid cycle. In plants...
    25 KB (2,304 words) - 18:35, 7 October 2024
  • Thumbnail for Tretinoin
    Tretinoin, also known as all-trans retinoic acid (ATRA), is a medication used for the treatment of acne and acute promyelocytic leukemia. For acne, it...
    31 KB (2,908 words) - 06:38, 22 September 2024
  • Thumbnail for Vitamin B6
    chlorophyll depends on aminolevulinic acid synthase, a PLP-dependent enzyme that uses succinyl-CoA and glycine to generate aminolevulinic acid, a chlorophyll...
    62 KB (7,074 words) - 19:18, 7 November 2024
  • Thumbnail for Metabolic pathway
    succinylacetone has been shown to decrease heme concentrations by inhibiting δ-aminolevulinic acid in murine erythroleukemia cells. The primary structure of heme-sequestering...
    26 KB (3,004 words) - 08:07, 11 November 2024
  • Thumbnail for Glycine
    Glycine (redirect from Aminoethanoic acid)
    starting with GG, namely GGU, GGC, GGA and GGG. In higher eukaryotes, δ-aminolevulinic acid, the key precursor to porphyrins, is biosynthesized from glycine...
    40 KB (3,766 words) - 11:02, 30 October 2024
  • Thumbnail for Leghemoglobin
    Root Nodules: I. On the Role of Bacteroid delta-Aminolevulinic Acid Synthase and delta-Aminolevulinic Acid Dehydrase in the Synthesis of the Heme of Leghemoglobin"...
    19 KB (2,221 words) - 18:48, 12 August 2024
  • Thumbnail for Levulinic acid
    additives. The largest application of levulinic acid is its use in the production of aminolevulinic acid, a biodegradable herbicide used in South Asia....
    8 KB (779 words) - 06:02, 20 April 2024
  • Thumbnail for Glioblastoma
    increased if the surgery is guided by a fluorescent dye known as 5-aminolevulinic acid. GBM cells are widely infiltrative through the brain at diagnosis...
    78 KB (8,704 words) - 00:23, 13 November 2024
  • Thumbnail for Epidermodysplasia verruciformis
    to treat the lesions include ALA-PDT (photodynamic therapy with aminolevulinic acid), applying 5-FU, imiquimod, and retinoids by mouth. The lesions tend...
    23 KB (2,379 words) - 15:19, 28 September 2024
  • Thumbnail for Heme
    initiated by the synthesis of δ-aminolevulinic acid (dALA or δALA) from the amino acid glycine and succinyl-CoA from the citric acid cycle (Krebs cycle). The...
    42 KB (4,371 words) - 06:57, 29 September 2024
  • pharmaceutical company. Hexaminolevulinate is a structural analogue to 5-aminolevulinic acid (a precursor to the porphyrin ring of heme), and is internalized...
    4 KB (139 words) - 03:10, 19 April 2024
  • Thumbnail for Cobalamin biosynthesis
    Many steps are involved in converting aminolevulinic acid via uroporphyrinogen III and adenosylcobyric acid to the final forms in which it is used by...
    36 KB (3,654 words) - 20:12, 4 September 2024
  • Thumbnail for Photodynamic therapy
    They divide into porphyrins, chlorins and dyes. Examples include aminolevulinic acid (ALA), Silicon Phthalocyanine Pc 4, m-tetrahydroxyphenylchlorin (mTHPC)...
    79 KB (9,506 words) - 22:52, 7 November 2024
  • Thumbnail for RNA interference
    givosiran received EMA approval. Givosiran is an siRNA that breaks down aminolevulinic acid synthase 1 (ALAS1) mRNA in the liver. Breaking down ALAS1 mRNA prevents...
    140 KB (15,409 words) - 08:23, 28 October 2024
  • Thumbnail for Lead poisoning
    precursors, such as aminolevulinic acid, which may be directly or indirectly harmful to neurons. Elevation of aminolevulinic acid results in lead poisoning...
    198 KB (21,311 words) - 22:25, 15 November 2024
  • H3 receptor agonist Aminolevulinic acid/sodium ferrous citrate (5-ALA-SFC, 5-ALA/SFX; sodium ferrous citrate/aminolevulinic acid; SPP-003) – erythropoiesis...
    38 KB (3,022 words) - 17:10, 10 November 2024
  • Thumbnail for Acne
    Acne (section Azelaic acid)
    following the application of a sensitizing substance to the skin such as aminolevulinic acid or methyl aminolevulinate, the treatment is referred to as photodynamic...
    167 KB (18,117 words) - 13:16, 13 November 2024
  • Thumbnail for Antimetabolite
    interfere with, such as the antifolates that interfere with the use of folic acid; thus, competitive inhibition can occur, and the presence of antimetabolites...
    12 KB (1,314 words) - 05:55, 8 July 2024
  • of colorectal cancer. It is made up of the following drugs: FOL – folinic acid (leucovorin), a vitamin B derivative with multiple applications, which in...
    4 KB (411 words) - 21:05, 6 May 2024
  • of δ-aminolevulinic acid, which can cause the acute symptoms in an attack of the acute porphyrias. Acute intermittent porphyria Aminolevulinic acid Inborn...
    3 KB (181 words) - 21:05, 27 July 2024
  • Thumbnail for Chlorophyll
    precursor. In angiosperms, this regulation is achieved at the step of aminolevulinic acid (ALA), one of the intermediate compounds in the biosynthesis pathway...
    35 KB (3,529 words) - 23:16, 5 November 2024
  • Thumbnail for Lead(II) nitrate
    known to substitute for zinc in a number of enzymes, including δ-aminolevulinic acid dehydratase (porphobilinogen synthase) in the haem biosynthetic pathway...
    20 KB (1,918 words) - 14:49, 4 October 2024
  • Thumbnail for Iron deficiency (plant disorder)
    glutamyl-tRNA reductase, an enzyme needed for the formation of 5-Aminolevulinic acid which is a precursor of heme and chlorophyll. Yellowing (Chlorosis)...
    5 KB (627 words) - 06:29, 25 June 2024