Amylin, or islet amyloid polypeptide (IAPP), is a 37-residue peptide hormone. It is co-secreted with insulin from the pancreatic β-cells in the ratio of...

In molecular biology, the amylin protein family or calcitonin/CGRP/IAPP protein family is a family of proteins, which includes the precursors of calcitonin/calcitonin...

Dual amylin and calcitonin receptor agonists (DACRAs) are a class of drugs that act as agonists at the amylin receptor and calcitonin receptor that are...

(trade name Symlin) is an injectable amylin analogue drug for diabetes (both type 1 and 2), developed by Amylin Pharmaceuticals (now a wholly owned subsidiary...

diabetes. CCL2 induces amylin expression through ERK1/ERK2/JNK-AP1 and NF-κB related signaling pathways independent of CCR2. Amylin upregulation by CCL2...

gene-related peptide (CGRP) is a member of the calcitonin family of peptides consisting of calcitonin, amylin, adrenomedullin, adrenomedullin 2 (intermedin) and...

evidence has been reached. This hormone stimulates growth hormone release. Amylin controls glucose homeostasis and gastric motility Glucose-dependent insulinotropic...

tirzepatide, are also agonists of the GIP receptor, glucagon receptor, and/or amylin receptor. These additional targets are hoped to improve the amount of weight...

(POMC) peptides Enkephalin pentapeptides Prodynorphin peptides Calcitonin Amylin AGG01 Aromatic short peptides Biomimetic peptides Peptide amphiphiles Peptide...

proposed debt swap. In April 2009, Icahn engaged in a proxy battle for Amylin. In September 2009, he offered to buy the shares of XO he did not already...

Motilin is a 22-amino acid polypeptide hormone in the motilin family that, in humans, is encoded by the MLN gene. Motilin is secreted by endocrine Mo cells...

amylin, a peptide hormone co-secreted with insulin from the pancreatic β cells. As plasma glucose levels recede, the subsequent reduction in amylin secretion...

Relaxin family peptide hormones in humans are represented by seven members: three relaxin-like (RLN) and four insulin-like (INSL) peptides: RLN1, RLN2...

hyperplasia indicates that use is contraindicated in people with a personal or family history of medullary thyroid carcinoma or with multiple endocrine neoplasia...

The RFamide peptide family, or the RFamide-related peptides (RFRPs), are a family of neuropeptides. They are characterized by the possession of an Arg-Phe-NH2...

of these medications include the following: Pramlintide (Symlin): is an Amylin agonist. It acts centrally (via the brain) to reduce food intake and blood...

date. Tirzepatide is contraindicated for use in people with a personal or family history of medullary thyroid cancer or for use in people with multiple endocrine...

EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. Besides EGF itself other family members...

(theophylline), diabetes drugs (acarbose, metformin, Alpha-glucosidase inhibitor, amylin analogs, GLP-1 receptor antagonists), antihypertensive medications (angiotensin...

acquisition of the biotechnology company Amylin Pharmaceuticals. It was agreed that Bristol Myers Squibb would acquire Amylin for $5.3 billion in cash and the...

endocrine pancreas and the gut. Amylin is another substance that can reduce body weight, and that may interact with IL-6. Amylin-induced IL-6 production in...

who are pregnant is not recommended. Gliclazide is in the sulfonylurea family of medications. It works mostly by increasing the release of insulin. Gliclazide...

when it agreed to buy Amylin Pharmaceuticals for around US$5.3 billion in cash and pay US$1.7 billion to Eli Lilly to cover Amylin's debt and its outstanding...

cells in the anterior pituitary. The GHRHR is a member of the secretin family of G protein-coupled receptors, and is located on chromosome 7 in humans...

action was linked to circulating blood fractions – now understood to be a family of androgenic hormones – in the early work on castration and testicular...

Central Drugs Standard Control Organization, Dte.GHS, Ministry of Health and Family Welfare, Government of India. Archived from the original on 21 February...

proteins that are made of acidic polypeptides and belongs to the TGF-B family. BMPs promote the regeneration of bone tissue and cartilage. BMP exhibits...

September 2002, Lilly agreed to partner with Amylin Pharmaceuticals to develop and commercialize Amylin's exotic new drug based on exendin-4, a novel substance...

2005. RAND Corporation: chairman of the board from 1981 to 1986; 1995–1996 Amylin Pharmaceuticals: director Secretary of Defense Donald Rumsfeld and Chairman...

Administration for treating type 1 diabetes is the amylin analog pramlintide, which replaces the beta-cell hormone amylin. Addition of pramlintide to mealtime insulin...