• Thumbnail for Amyloid
    Amyloids are aggregates of proteins characterised by a fibrillar morphology of typically 7–13 nm in diameter, a β-sheet secondary structure (known as cross-β)...
    60 KB (6,536 words) - 06:48, 29 August 2024
  • Thumbnail for Amyloid beta
    Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with...
    44 KB (4,830 words) - 18:56, 11 August 2024
  • Amyloidosis is a group of diseases in which abnormal proteins, known as amyloid fibrils, build up in tissue. There are several non-specific and vague signs...
    55 KB (5,426 words) - 23:43, 23 June 2024
  • Thumbnail for Cerebral amyloid angiopathy
    Cerebral amyloid angiopathy (CAA) is a form of angiopathy in which amyloid beta peptide deposits in the walls of small to medium blood vessels of the...
    18 KB (1,768 words) - 14:27, 21 August 2024
  • up amyloid in Wiktionary, the free dictionary. An amyloid is any of certain insoluble fibrous protein aggregates. Amyloid may also refer to: Amyloid (mycology)...
    494 bytes (90 words) - 11:42, 22 July 2015
  • Lecanemab (category Anti-amyloid monoclonal antibodies)
    infusion-related reactions, and amyloid-related imaging abnormalities, a side effect known to occur with the class of antibodies targeting amyloid. Lecanemab was granted...
    27 KB (2,350 words) - 14:54, 23 August 2024
  • Thumbnail for Amyloid plaques
    Amyloid plaques (also known as neuritic plaques, amyloid beta plaques or senile plaques) are extracellular deposits of the amyloid beta (Aβ) protein mainly...
    31 KB (3,370 words) - 18:46, 11 August 2024
  • Thumbnail for Amyloid-beta precursor protein
    Amyloid-beta precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. It functions...
    50 KB (5,683 words) - 05:16, 29 June 2024
  • Thumbnail for Amylin
    Amylin, or islet amyloid polypeptide (IAPP), is a 37-residue peptide hormone. It is co-secreted with insulin from the pancreatic β-cells in the ratio...
    33 KB (4,044 words) - 20:39, 24 August 2024
  • Thumbnail for Alzheimer's disease
    progress of the protein misfolding disease is largely associated with amyloid plaques, neurofibrillary tangles, and loss of neuronal connections in the...
    182 KB (19,287 words) - 19:52, 23 August 2024
  • Amyloid light-chain (AL) amyloidosis, also known as primary amyloidosis, is the most common form of systemic amyloidosis. The disease is caused when a...
    16 KB (1,638 words) - 03:32, 26 August 2024
  • In mycology a tissue or feature is said to be amyloid if it has a positive amyloid reaction when subjected to a crude chemical test using iodine as an...
    8 KB (1,449 words) - 12:54, 22 June 2023
  • Serum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. Different isoforms of SAA are...
    7 KB (742 words) - 21:46, 27 November 2023
  • Amyloid: the Journal of Protein Folding Disorders is a peer-reviewed scientific journal that publishes original research and review articles on all aspects...
    3 KB (194 words) - 11:43, 26 April 2023
  • Amyloid cardiomyopathy (stiff heart syndrome) is a condition resulting in the death of part of the myocardium (heart muscle). It is associated with the...
    7 KB (514 words) - 01:41, 18 June 2024
  • Amyloid-related imaging abnormalities (ARIA) are abnormal differences seen in magnetic resonance imaging of the brain in patients with Alzheimer's disease...
    10 KB (780 words) - 07:19, 3 August 2024
  • Thumbnail for Amyloid purpura
    Amyloid purpura is a condition marked by bleeding under the skin (purpura) in some individuals with amyloidosis. Its cause is unknown, but coagulation...
    3 KB (258 words) - 01:42, 18 June 2024
  • Thumbnail for Proteinopathy
    cellulose, "amyloid" actually is rich in protein. Subsequent research has shown that many different proteins can form amyloid, and that all amyloids show birefringence...
    62 KB (4,598 words) - 09:51, 31 July 2024
  • Anti-amyloid drugs, also known as anti-amyloid antibodies (AAA), are a class of monoclonal antibodies developed to treat Alzheimer's disease. The first...
    8 KB (2,265 words) - 06:25, 6 August 2024
  • Thumbnail for Familial amyloid polyneuropathy
    Familial amyloid polyneuropathy, also called transthyretin-related hereditary amyloidosis, transthyretin amyloidosis abbreviated also as ATTR (hereditary...
    14 KB (1,486 words) - 16:53, 7 February 2024
  • Familial amyloid cardiomyopathy (FAC), or transthyretin amyloid cardiomyopathy (ATTR-CM) results from the aggregation and deposition of mutant and wild-type...
    7 KB (791 words) - 14:15, 22 August 2023
  • disease due to the accumulation of abnormally folded amyloid beta (Aβ) protein in the brain. Amyloid beta is a short peptide that is an abnormal proteolytic...
    65 KB (7,761 words) - 08:45, 1 July 2024
  • protein has been identified as part of the enzymatic complex that cleaves amyloid-beta peptide from APP. The gene contains 14 exons, and the coding portion...
    32 KB (3,621 words) - 18:23, 29 August 2024
  • is the primary author of a controversial 2006 Nature paper, "A specific amyloid-β protein assembly in the brain impairs memory". Lesné's work in the 2006...
    35 KB (3,538 words) - 18:44, 29 August 2024
  • Thumbnail for Cardiac amyloidosis
    amyloidosis where there is depositing of the protein amyloid in the cardiac muscle and surrounding tissues. Amyloid, a misfolded and insoluble protein, can become...
    30 KB (3,354 words) - 02:30, 21 June 2024
  • tissues and organs. In AA amyloidosis, the deposited protein is serum amyloid A protein (SAA), an acute-phase protein which is normally soluble and whose...
    17 KB (1,507 words) - 02:50, 7 July 2024
  • Thumbnail for Prion
    can form a fibril, leading to abnormal protein aggregates called amyloids. These amyloids accumulate in infected tissue, causing damage and cell death. The...
    99 KB (10,711 words) - 19:55, 29 August 2024
  • Donanemab (category Anti-amyloid monoclonal antibodies)
    developed by Eli Lilly and Company. The most common side effects include amyloid-related imaging abnormalities and headache. Donanemab was approved for...
    20 KB (1,992 words) - 04:29, 15 August 2024
  • Thumbnail for Transthyretin
    associated with amyloid diseases including wild-type transthyretin amyloidosis, hereditary transthyretin amyloidosis, familial amyloid polyneuropathy (FAP)...
    20 KB (2,382 words) - 16:13, 22 January 2024
  • The familial amyloid neuropathies (or familial amyloidotic neuropathies, neuropathic heredofamilial amyloidosis, familial amyloid polyneuropathy) are a...
    6 KB (505 words) - 14:56, 27 October 2023