Amyloids are aggregates of proteins characterised by a fibrillar morphology of typically 7–13 nm in diameter, a β-sheet secondary structure (known as cross-β)...
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Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with...
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Amyloidosis (redirect from Amyloid degeneration)
Amyloidosis is a group of diseases in which abnormal proteins, known as amyloid fibrils, build up in tissue. There are several non-specific and vague signs...
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Cerebral amyloid angiopathy (CAA) is a form of angiopathy in which amyloid beta peptide deposits in the walls of small to medium blood vessels of the...
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up amyloid in Wiktionary, the free dictionary. An amyloid is any of certain insoluble fibrous protein aggregates. Amyloid may also refer to: Amyloid (mycology)...
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Lecanemab (category Anti-amyloid monoclonal antibodies)
infusion-related reactions, and amyloid-related imaging abnormalities, a side effect known to occur with the class of antibodies targeting amyloid. Lecanemab was granted...
27 KB (2,350 words) - 14:54, 23 August 2024
Amyloid plaques (also known as neuritic plaques, amyloid beta plaques or senile plaques) are extracellular deposits of the amyloid beta (Aβ) protein mainly...
31 KB (3,370 words) - 18:46, 11 August 2024
Amyloid-beta precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. It functions...
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Amylin (redirect from Pro-islet amyloid polypeptide)
Amylin, or islet amyloid polypeptide (IAPP), is a 37-residue peptide hormone. It is co-secreted with insulin from the pancreatic β-cells in the ratio...
33 KB (4,044 words) - 20:39, 24 August 2024
progress of the protein misfolding disease is largely associated with amyloid plaques, neurofibrillary tangles, and loss of neuronal connections in the...
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AL amyloidosis (redirect from Amyloid light chain)
Amyloid light-chain (AL) amyloidosis, also known as primary amyloidosis, is the most common form of systemic amyloidosis. The disease is caused when a...
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In mycology a tissue or feature is said to be amyloid if it has a positive amyloid reaction when subjected to a crude chemical test using iodine as an...
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Serum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. Different isoforms of SAA are...
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Amyloid: the Journal of Protein Folding Disorders is a peer-reviewed scientific journal that publishes original research and review articles on all aspects...
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Amyloid cardiomyopathy (stiff heart syndrome) is a condition resulting in the death of part of the myocardium (heart muscle). It is associated with the...
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Amyloid-related imaging abnormalities (ARIA) are abnormal differences seen in magnetic resonance imaging of the brain in patients with Alzheimer's disease...
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Amyloid purpura is a condition marked by bleeding under the skin (purpura) in some individuals with amyloidosis. Its cause is unknown, but coagulation...
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cellulose, "amyloid" actually is rich in protein. Subsequent research has shown that many different proteins can form amyloid, and that all amyloids show birefringence...
62 KB (4,598 words) - 09:51, 31 July 2024
Anti-amyloid drugs, also known as anti-amyloid antibodies (AAA), are a class of monoclonal antibodies developed to treat Alzheimer's disease. The first...
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Familial amyloid polyneuropathy, also called transthyretin-related hereditary amyloidosis, transthyretin amyloidosis abbreviated also as ATTR (hereditary...
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Familial amyloid cardiomyopathy (FAC), or transthyretin amyloid cardiomyopathy (ATTR-CM) results from the aggregation and deposition of mutant and wild-type...
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Biochemistry of Alzheimer's disease (redirect from Amyloid hypothesis)
disease due to the accumulation of abnormally folded amyloid beta (Aβ) protein in the brain. Amyloid beta is a short peptide that is an abnormal proteolytic...
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protein has been identified as part of the enzymatic complex that cleaves amyloid-beta peptide from APP. The gene contains 14 exons, and the coding portion...
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Sylvain Lesné (redirect from Amyloid beta star 56)
is the primary author of a controversial 2006 Nature paper, "A specific amyloid-β protein assembly in the brain impairs memory". Lesné's work in the 2006...
35 KB (3,538 words) - 18:44, 29 August 2024
amyloidosis where there is depositing of the protein amyloid in the cardiac muscle and surrounding tissues. Amyloid, a misfolded and insoluble protein, can become...
30 KB (3,354 words) - 02:30, 21 June 2024
AA amyloidosis (redirect from Amyloid associated)
tissues and organs. In AA amyloidosis, the deposited protein is serum amyloid A protein (SAA), an acute-phase protein which is normally soluble and whose...
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can form a fibril, leading to abnormal protein aggregates called amyloids. These amyloids accumulate in infected tissue, causing damage and cell death. The...
99 KB (10,711 words) - 19:55, 29 August 2024
Donanemab (category Anti-amyloid monoclonal antibodies)
developed by Eli Lilly and Company. The most common side effects include amyloid-related imaging abnormalities and headache. Donanemab was approved for...
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associated with amyloid diseases including wild-type transthyretin amyloidosis, hereditary transthyretin amyloidosis, familial amyloid polyneuropathy (FAP)...
20 KB (2,382 words) - 16:13, 22 January 2024
The familial amyloid neuropathies (or familial amyloidotic neuropathies, neuropathic heredofamilial amyloidosis, familial amyloid polyneuropathy) are a...
6 KB (505 words) - 14:56, 27 October 2023