Anti–vascular endothelial growth factor therapy, also known as anti-VEGF (/vɛdʒˈɛf/) therapy or medication, is the use of medications that block vascular...
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Vascular endothelial growth factor (redirect from VEGF)
Vascular endothelial growth factor (VEGF, /vɛdʒˈɛf/), originally known as vascular permeability factor (VPF), is a signal protein produced by many cells...
40 KB (4,580 words) - 05:24, 3 June 2024
Diabetic retinopathy (section Intravitreal anti-VEGF)
retinopathy. There are four common treatments for diabetic retinopathy: anti-VEGF injections, steroid injections, panretinal laser photocoagulation, and...
51 KB (5,611 words) - 02:40, 29 July 2024
or treatment that restores the vision already lost. In the wet form, anti-VEGF medication injected into the eye or, less commonly, laser coagulation...
90 KB (9,840 words) - 22:49, 25 August 2024
Intravitreal injection (section Anti-VEGF drugs)
injection. At the end of the year, on December 17, the first intravitreal anti-VEGF drug pegaptanib (Macugen) was also licensed by FDA for treatment of wet...
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Angiogenesis inhibitor (redirect from Anti-angiogenesis)
of bleeding induced by anti-VEGF agents are complicated and not yet totally understood, the most accepted hypothesis is that VEGF could promote endothelial...
33 KB (3,229 words) - 19:54, 7 July 2024
performed. This doubled to 2 million just 3 years later in 2011 when another anti-VEGF intravitreal injection aflibercept became available for the treatment...
19 KB (2,323 words) - 01:07, 6 August 2024
it is no longer used in age-related macular degeneration in favor of anti-VEGF drugs. The American Academy of Ophthalmology practice guidelines recommend...
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treatment for CNV is to inhibit VEGF activity by competing the binding of VEGF with specific neutralizing anti-VEGF antibody. VEGF inhibitors include pegaptanib...
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Glaucoma (redirect from Anti-glaucoma)
that anti-VEGF medications are effective either for short-term or for longer-term treatment. The short, medium, and long-term safety of anti-VEGF treatment...
90 KB (9,912 words) - 00:07, 29 August 2024
vessels by inhibiting vascular endothelial growth factor A (VEGF-A), in other words anti–VEGF therapy. Bevacizumab was approved for medical use in the United...
73 KB (6,440 words) - 06:25, 18 August 2024
Vascular endothelial growth factor (VEGF) seems to play a vital role in promoting neovascularization. Using anti-VEGF drugs (antibodies to sequester the...
19 KB (2,059 words) - 20:05, 20 July 2024
any additional benefit of combining anti-VEGF and intravitreal steroids when compared to either treatment alone. Anti‐tumour necrosis factor agents have...
16 KB (1,554 words) - 03:45, 22 August 2024
of anti-VEGF therapy in the uveitis treatment regimen can be fully determined. The anti VEGF agents furthermore have not been shown to have an anti-inflammatory...
7 KB (1,058 words) - 22:47, 26 November 2018
Angiogenesis (section VEGF)
retinal fluids leak into the retina, causing loss of vision. Anti-angiogenic drugs targeting the VEGF pathways are now used successfully to treat this type of...
50 KB (5,880 words) - 07:16, 28 August 2024
reducing macular edema. Drug trials have found it to be as efficient as anti-VEGF drugs in eyes with artificial lenses over a two-year period. A systematic...
16 KB (1,220 words) - 08:36, 1 July 2024
growth factor (VEGF) in eye disease and demonstrated the therapeutic potential of VEGF inhibitors, forming the scientific basis of anti-VEGF therapy for...
30 KB (2,896 words) - 12:43, 13 April 2024
ALK inhibitor (section Anti-VEGF therapies)
only inhibits EGFR). Several trials are investigating the combination of anti-VEGF antibody bevacizumab with ALK inhibitors such as alectinib and brigatinib...
17 KB (1,951 words) - 10:39, 25 January 2024
and irinotecan-based chemotherapy, an anti-VEGF therapy, and, if RAS wild-type and medically appropriate, an anti-EGFR therapy. Efficacy was evaluated...
10 KB (579 words) - 06:46, 26 June 2024
and chronic kidney injuries. Newer agents such as anti-vascular endothelial growth factor (anti-VEGF) are also associated with similar injuries, as well...
24 KB (2,616 words) - 02:49, 13 August 2024
with intravitreal injections of angiogenesis inhibitors (also known as "anti-VEGF" drugs) to control neovascularization and reduce the area of fluid below...
7 KB (833 words) - 05:58, 1 January 2024
Vascular endothelial growth factor A (redirect from VEGF-A)
Vascular endothelial growth factor A (VEGF-A) is a protein that in humans is encoded by the VEGFA gene. This gene is a member of the platelet-derived growth...
24 KB (3,053 words) - 21:43, 17 August 2024
growth factor (VEGF) inhibitor used to treat neovascular age-related macular degeneration (AMD) and diabetic macular edema (DME). The anti-VEGF was approved...
16 KB (1,699 words) - 22:49, 9 February 2024
retinal disorder, neovascular age-related macular degeneration, local anti-VEGF therapy to limit the bio-activity of vascular endothelial growth factor...
26 KB (2,931 words) - 18:31, 30 July 2024
of FSH and FSH-receptor antagonists as an anti-tumor angiogenesis therapy (cf. avastin for current anti-VEGF approaches). EFSH, a follicle-stimulating...
21 KB (2,261 words) - 03:48, 13 June 2024
thrombosis) in patients with retinal vascular occlusion. Treatment consists of Anti-VEGF drugs like Lucentis or intravitreal steroid implant (Ozurdex) and Pan-Retinal...
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(AMD), and diabetic retinopathy. At Genentech, he discovered VEGF—and made the first anti-VEGF antibody—which suppresses growth of a variety of tumors. These...
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injections of anti-VEGF agents, namely bevacizumab, a humanized monoclonal antibody targeted against pro-angiogenic, circulatory VEGF; and ranibizumab...
19 KB (2,217 words) - 18:58, 27 September 2023
Epithelioid sarcoma (section VEGF)
vessels, which provide necessary elements to the tumor for tumor survival. Anti-VEGF agents such as pazopanib are approved for use in carcinomas and in soft...
52 KB (5,913 words) - 20:45, 30 May 2024
Several anti-angiogenesis drugs approved for other conditions, such as cancer, have been investigated in small clinical trials. The anti-VEGF antibody...
49 KB (5,782 words) - 03:08, 4 August 2024