Diethylstilbestrol (DES), a synthetic nonsteroidal estrogen which was previously used clinically to support pregnancy, has been linked to a variety of...

A birth defect is an abnormal condition that is present at birth, regardless of its cause. Birth defects may result in disabilities that may be physical...

Diethylstilbestrol (DES), also known as stilbestrol or stilboestrol, is a nonsteroidal estrogen medication, which is presently rarely used. In the past...

(June 2013). "Exposure to diethylstilbestrol during sensitive life stages: a legacy of heritable health effects". Birth Defects Research. Part C, Embryo...

upon examination shortly after birth or when the development of sexual characteristics does not progress as expected. Defects that prevent menstrual flow...

drugs like diethylstilbestrol (DES) has been linked to genital abnormalities or a smaller than normal penis. After evaluation to detect any of the conditions...

lack of evidence regarding the drug's safety. Her concerns proved to be justified when it was shown that thalidomide caused serious birth defects. Kelsey's...

crucial time for the action of any teratogenic substances to result in birth defects. Once fertilization has taken place, the toxicants in the environment...

state in eighty of his infertility patients with continuous gradually increasing oral doses of an estrogen (5 to 30 mg/day diethylstilbestrol) and progesterone...

Children born to mothers who had ingested the endocrine disruptor diethylstilbestrol for potential miscarriage Traumatic brain injury, even in childhood...

risk of preeclampsia and miscarriage and can lead to birth defects. Lead is believed to predominantly affect male reproduction by the disruption of hormones...

history of conization (cervical biopsy) diethylstilbestrol exposure, which can cause anatomical defects, and uterine anomalies Diagnosis of cervical...

women who did not plan to breastfeed were given diethylstilbestrol and other medications after birth to suppress lactation. However, its use was discontinued...

to an equivalent extent as 3 mg/day oral diethylstilbestrol, which is the minimum dosage of diethylstilbestrol required to consistently suppress testosterone...

for a fetus. The birth defects crisis due to the medication thalidomide in the 1960s, where thousands of children were born with defects ranging from brain...

uterus. The uterine cavity has a "T-shape" as a result of fetal exposure to diethylstilbestrol. An additional variation is the arcuate uterus where there...

theoretical risk of birth defects in male fetuses. In the Early Prostate Cancer (EPC) clinical trial programme, at 7.4 years follow-up, the rate of hot flashes...

identified and removed from the market (for example, a drug called diethylstilbestrol), but it is uncertain whether some endocrine disruptors on the market...

cause birth defects. However, the guidelines were interpreted to exclude pregnant women from any clinical trial. Despite a 1994 National Academy of Medicine...

months of pregnancy because of past reports of genital birth defects (an increased risk of hypospadias in male fetuses and mild virilization of vulvas...

endometriosis. One advantage of using GnRH antagonists is that repeated administration of GnRH agonists results in decreased levels of gonadotropins and sex...

could cause serious birth defects. Estrogen passes into the breast milk and will cause a decrease in the production and quality of breast milk. To effectively...

with low fetal weight and heart, urinary, and limb defects in humans". Incidence of a birth defect known as gastroschisis appears to be higher in areas...

birth defects, which occur in approximately 6% of exposed children, include neural tube defects, heart defects and craniofacial abnormalities, including broad...

to an equivalent extent as 3 mg/day oral diethylstilbestrol, which is the minimum dosage of diethylstilbestrol required to consistently suppress total...

levomefolic acid to lower the risk of complications such as fetal neural tube defects should the medication fail as a form of birth control. EE/DRSP/LMF was approved...

studied in the treatment of prostate cancer but was found to be inferior to monotherapy with cyproterone acetate or diethylstilbestrol. High-dose oral MPA...

pain at the site of injection. Use in those with liver disease is not recommended as is use during pregnancy due to risk of birth defects. Use appears to...

conference on birth defects. She reported on a group of intersex children in the Caribbean who appeared sexually ambiguous at birth, and were initially...

Numerous cases of liver failure and death have been reported, which has limited the use of flutamide. Flutamide acts as a selective antagonist of the androgen...