• Thumbnail for T-box transcription factor T
    transcription factor T, also known as Brachyury protein, is encoded for in humans by the TBXT gene. Brachyury functions as a transcription factor within...
    34 KB (3,939 words) - 23:09, 15 January 2024
  • Thumbnail for Chordoma
    been affected by chordoma. In four of these families, duplication of the brachyury gene was found to be responsible for causing chordoma. A possible association...
    21 KB (2,187 words) - 14:39, 28 May 2024
  • Thumbnail for T-box
    protein encoded was named brachyury, Greek for "short-tail". In mice this gene is named Tbxt, and in humans it is named TBXT. Brachyury has been found in all...
    10 KB (1,078 words) - 03:27, 30 November 2023
  • Thumbnail for Primitive streak
    factors (Vg1, Nodal, Wnt8C, FGF8 and Chordin) and transcription factors (Brachyury and Goosecoid) adjacent to the site of streak formation is required for...
    23 KB (2,803 words) - 21:33, 7 April 2024
  • Thumbnail for Gastruloid
    conditions derived from directed differentiation of ESCs in adherent culture Brachyury (T/Bra), a gene which marks the primitive streak and the site of gastrulation...
    15 KB (1,666 words) - 19:23, 24 July 2024
  • Thumbnail for Gastrulation
    epiblast cells that traverse through the primitive streak (e.g. transient brachyury up regulation and the cellular changes associated with an epithelial to...
    38 KB (4,044 words) - 18:10, 14 March 2024
  • Thumbnail for Manx cat
    initiation of the Manx Cat Genome Project (below), genetic mutations in the brachyury gene were shown to be responsible for failure of tail development in the...
    71 KB (7,692 words) - 05:20, 14 August 2024
  • Thumbnail for Notochord
    identification of notochord enhancers comprising the regulatory landscape of the brachyury locus in mouse. Development (Cambridge, England), 150(22). https://doi...
    21 KB (2,359 words) - 16:17, 29 August 2024
  • Thumbnail for Chromosome 6
    doi:10.1038/346561a0. PMID 2165569. S2CID 4356509. "T brachyury transcription factor". T - T brachyury transcription factor - Genetics Home Reference. Genome...
    35 KB (2,420 words) - 20:57, 24 August 2024
  • Xbra is a homologue of Brachyury (T) gene for Xenopus. It is a transcription activator involved in vertebrate gastrulation which controls posterior mesoderm...
    4 KB (507 words) - 13:04, 18 August 2023
  • (brakhús) amphibrach, brachistochrone, brachycephaly, brachydactyly, brachyury, dibrach, tribrach brady-, bradys- slow Greek βραδύς (bradús), βράδος...
    2 KB (1,500 words) - 00:54, 30 August 2024
  • on developmental genetics. Her research showed that mutations in the Brachyury gene of the mouse caused the aberrant development of the posterior portion...
    11 KB (984 words) - 13:11, 20 July 2024
  • Thumbnail for Claudia M. Palena
    shown that brachyury is overexpressed in various human carcinomas, both in the primary tumor and in metastatic sites, and that high brachyury expression...
    5 KB (504 words) - 18:37, 6 July 2024
  • Thumbnail for Braque du Bourbonnais
    pointer", the braque du Bourbonnais is sometimes born with a short tail (brachyury) or no tail at all (anury). The gene responsible for this characteristic...
    6 KB (599 words) - 11:18, 6 July 2024
  • transcription factors (2). In particular, three T box transcription factors, Brachyury (frogs) or No tail (fish) (10), VegT (frog) or Spadetail (fish), and Tbx6...
    10 KB (1,399 words) - 14:41, 14 July 2024
  • Satoh, Nori (September 2000). "The expression of nonchordate deuterostome Brachyury genes in the ascidian Ciona embryo can promote the differentiation of...
    5 KB (448 words) - 08:53, 25 April 2023
  • stomochord, or between the notochord and any hemichordate structure. The Brachyury (T) gene, which is expressed in the ascidian and other chordates notochord...
    2 KB (186 words) - 14:19, 6 November 2020
  • acids of DNA T, gene and protein symbol for the transcription factor brachyury Thoracic vertebrae T-1 through T-12 T wave, the repolarization wave of...
    7 KB (968 words) - 22:47, 31 May 2024
  • Thumbnail for Mesozoa
    lophotrochozoans: insight from the expression patterns of Hox, Otx, and brachyury". Evolution & Development. 11 (5): 582–589. doi:10.1111/j.1525-142X.2009...
    10 KB (1,070 words) - 06:14, 25 July 2024
  • Thumbnail for Jim Cuthbert Smith
    cell types at different thresholds and that characteristic genes like Brachyury are turned on at specific concentrations. In other work he shed light...
    12 KB (1,093 words) - 18:34, 17 May 2024
  • Thumbnail for Boris Ephrussi
    despite these obstacles Ephrussi managed to conclude from studies of brachyury in mice that intrinsic factors (i.e. genes) play a key role in development...
    8 KB (889 words) - 19:44, 6 July 2024
  • was a Brachyury gene, a marker of mesoderm differentiation and is only slightly expressed in undifferentiated embryonic stem cells. "Brachyury" was induced...
    28 KB (3,692 words) - 22:45, 3 December 2023
  • Thumbnail for Nadiya Dobrovolska-Zavadska
    Paris. There she made a genetic and oncology research career discovering Brachyury gene in mice. Also she established RIII mouse strain which helped to discover...
    5 KB (461 words) - 23:09, 15 January 2024
  • Thumbnail for Dicyemida
    lophotrochozoans: insight from the expression patterns of Hox, Otx, and brachyury". Evol Dev. 11 (5): 582–589. doi:10.1111/j.1525-142x.2009.00364.x. PMID 19754714...
    14 KB (1,666 words) - 15:18, 3 July 2024
  • tumor cells can adapt to promote disease recurrence and progression. Brachyury, Axl, MEK, and Aurora kinase A are molecular drivers of these programs...
    59 KB (6,836 words) - 03:14, 26 August 2024
  • Thumbnail for Embryoid body
    parallels to embryonic development such as symmetry-breaking, localised brachyury expression, the formation of the embryonic axes (anteroposterior, dorsoventral...
    45 KB (4,513 words) - 01:22, 22 June 2024
  • Thumbnail for Oikopleura dioica
    these simple chordates and in higher vertebrates. As an example, the brachyury gene and the homolog of the PAX2 gene both play a similar role in the...
    7 KB (787 words) - 02:52, 8 July 2024
  • Thumbnail for Trichoplax
    has, however, already been possible to identify several genes, such as Brachyury and TBX2/TBX3, which are homologous to corresponding base-pair sequences...
    50 KB (6,031 words) - 21:08, 6 September 2024
  • Thumbnail for Suberites domuncula
    larvae which then develop into juvenile sponge. Suberites domuncula have a Brachyury gene that is associated with the formation of the limbs. This gene has...
    12 KB (1,333 words) - 03:32, 19 February 2024
  • Thumbnail for T-complex 1
    Edwards YH (1997). "Genetic mapping of the human homologue (T) of mouse T(Brachyury) and a search for allele association between human T and spina bifida"...
    9 KB (1,227 words) - 23:04, 26 March 2024