CIITA is a human gene which encodes a protein called the class II, major histocompatibility complex, transactivator. Mutations in this gene are responsible...

class II expression is closely regulated in APCs by CIITA, which is the MHC class II transactivator. CIITA is solely expressed on professional APCs; however...

type of N-terminal domain: NLRA (A for acidic transactivating domain): CIITA NLRB (B for BIRs): NAIP NLRC (C for CARD): NOD1, NOD2, NLRC3, NLRC4, NLRC5...

24% with Komo. The language is also called Opo-Shita, Opo, Opuo, Cita, Ciita, Shita (along with Dana), Shiita, Ansita, Kina, and Kwina. The self-name...

proteins that contain it: NAIP (NLP family apoptosis inhibitor protein), CIITA (that is, C2TA or MHC class II transcription activator), HET-E (incompatibility...

HGNC:1976 O60543 3059 CIDEB HGNC:1977 Q9UHD4 3060 CIDEC HGNC:24229 Q96AQ7 3061 CIITA HGNC:7067 P33076 3062 CILK1 HGNC:21219 Q9UPZ9 3063 CILP HGNC:1980 O75339...

Zinc finger, X-linked, duplicated family member C (ZXDC) is a human CIITA-binding protein involved in the activation of major histocompatibility complex...

prevent NK cells attacks due to deletion of HLA. Deletion of the B2M and CIITA genes using the CRISPR/Cas9 system has been reported to suppress the expression...

other proteins the most important are: the MHC Class II transactivator (CIITA), IPAF, BIRC1 etc. The ligands are currently known for NOD1 and NOD2. NOD1...

the general transcription factors TFIIE and TFIIF. Other proteins include CIITA, Brm (chromatin remodeler), NF-κB (p65), TAL1/SCL, Beta2/NeuroD, C/EBPβ...

A class II gene is a type of gene that codes for a protein. Class II genes are transcribed by RNAP II [citation needed]. Class II genes have a promoter...

of only two have been determined. RFX5 has been shown to interact with CIITA. GRCh38: Ensembl release 89: ENSG00000143390 – Ensembl, May 2017 GRCm38:...

genes can lead to BLS II. The genes' names are: class II trans-activator (CIITA) regulatory factor X5 (RFX5) RFX-associated protein (RFXAP) RFX ankyrin...

in TAP1, TAP2, TAPBP, or B2M) MHC class II deficiency (with mutations in CIITA, RFXANK, RFX5, or RFXAP) CD25 deficiency CD27 deficiency STAT5b deficiency...

histocompatibility class II (MHC II) DRA gene by IFN-gamma. Following induction of the CIITA transcription factor by IFN-gamma, there was recruitment of both CDK7 and...

the synthesis of these proteins, the CIITA or class II transcription activator. Selective gene targeting of CIITA has been used ex vivo to allow MHC class...

lymphocyte syndrome type II is due to mutations in any of the following genes: CIITA is responsible for giving instructions to create a protein that controls...

phosphorylated and ubiquitinated. MAPK1 has been shown to interact with: ADAM17, CIITA, DUSP1, DUSP3, ELK1, FHL2, HDAC4, MAP2K1, MAP3K1 MAPK14, MKNK1, MKNK2, Myc...

Interplay among coactivator-associated arginine methyltransferase 1, CBP, and CIITA in IFN-gamma-inducible MHC-II gene expression. Proc Natl Acad Sci U S A...

of multiple myeloma. XPO1 has been shown to interact with: APC, CDKN1B, CIITA, NMD3, Nucleoporin 62, RANBP1, RANBP3, Ran, SMARCB1, and p53. Karyopherin...

M, et al. (1998). "The RFX complex is crucial for the constitutive and CIITA-mediated transactivation of MHC class I and beta2-microglobulin genes"....

domain and has been shown to interact with: Androgen receptor, C-Fos, C-jun, CIITA, CREB-binding protein, Cyclin D1, DDX17, DDX5 and Estrogen receptor alpha...

Paliwal I, et al. (2003). "Human trophoblast noncoding RNA suppresses CIITA promoter III activity in murine B-lymphocytes". Biochem. Biophys. Res. Commun...

cells from viruses including COVID-19 and Ebola. They found that one gene, CIITA, can help human cells resist the virus by activating another gene, CD74...

Mahanta SK, Scholl T, Yang FC, Strominger JL (1997). "Transactivation by CIITA, the type II bare lymphocyte syndrome-associated factor, requires participation...

Egeland T, Undlien DE (September 2008). "Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency". The Journal...

class II molecule by direct expression cloning of the transcription factor CIITA". International Immunology. 7 (7): 1087–92. doi:10.1093/intimm/7.7.1087...

a family of NLR proteins that includes the transcriptional co-activator CIITA and the canonical inflammasome protein NLRP3. A truncated murine NLRC4 was...

Hake SB, Masternak K, Kammerbauer C, Janzen C, Reith W, Steimle V (2000). "CIITA leucine-rich repeats control nuclear localization, in vivo recruitment to...

lymphoma (DLBCL) and appears to suppress the immune system by silencing the CIITA gene. The transcription factor gene GATA3 is altered in mammary tumors....