Contactin-associated protein-like 2 is a protein that in humans is encoded by the CNTNAP2 gene. This gene encodes a member of the neurexin family which functions...

(January 2008). "Linkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility gene". American Journal of Human Genetics....

autosomal recessive mutations of the contactin associated protein like 2 (CNTNAP2) gene on the long arm of chromosome 7 (7q33-q36) and the neurexin 1 alpha...

known to regulate CNTNAP2, CTBP1, SRPX2 and SCN3A. FOXP2 downregulates CNTNAP2, a member of the neurexin family found in neurons. CNTNAP2 is associated with...

been shown to cause major issues to overall linguistic intelligence. The CNTNAP2 gene is believed to affect language development and performance, and mutations...

only a small number of cases in single families (the SLITRK1, HDC, and CNTNAP2 genes). Psychosocial or other non-genetic factors—while not causing Tourette's—can...

receptors (CELSR1, CELSR2, CELSR3), contactin-associated proteins (CNTNAP1, CNTNAP2, CNTNAP3, CNTNAP3B, CNTNAP4, CNTNAP5), some collagens (COL5A1, COL5A3,...

and the heterozygous mice have a lowered seizure threshold. Mutations of CNTNAP2 (the gene encoding CASPR2) have been reported to be associated with intellectual...

and subsequent functional characterization of the autism-related gene CNTNAP2 at UCLA. Abrahams is an assistant professor at the Albert Einstein College...

O94779 3314 CNTN6 HGNC:2176 Q9UQ52 3315 CNTNAP1 HGNC:8011 P78357 3316 CNTNAP2 HGNC:13830 Q9UHC6 3317 CNTNAP3 HGNC:13834 Q9BZ76 3318 CNTNAP3B HGNC:32035...

based on abnormalities in this and other neuropeptides. A mutation in the Cntnap2 gene, which has been linked to ASD in human, results in decreased oxytocin...

conducted in 2013 and 2015 discovered disease-associated SNPs near SORL1, CNTNAP2, SUDS3, FAM47E, and SCARB2. GWAS from Chinese cohorts identified SNPs in...

can be several hundred thousands bases long), for example genes RBFOX1, CNTNAP2, PTPRD and DLG2. Senapathy provided a plausible answer to these questions...

the second FA58C domain in MFGM Q08431. AEBP1; BTBD9; CASPR4; CNTNAP1; CNTNAP2; CNTNAP3; CNTNAP4; CNTNAP5; CPXM1; CPXM2; DCBLD1; DCBLD2; DDR1; DDR2; EDIL3;...

only a small number of cases in single families (the SLITRK1, HDC, and CNTNAP2 genes). In some cases, tics may not be inherited; these cases are identified...

frontal lobe circuits is associated with variation in the autism risk gene CNTNAP2." The study used a combination of genetics and imaging phenotypes to determine...

FRA6F FRA6G FRA6H FRA7A FRA7B FRA7C FRA7D FRA7E FRA7F FRA7G FRA7H FRA7I (CNTNAP2 gene) FRA7J FRA7K (IMMP2L gene) FRA8A FRA8B FRA8C FRA8D FRA8E FRA8F FRA9A...

in human and mouse models. Vernes also showed the relationship between CNTNAP2 and FOXP2, indicating that the pair can cause various language-related...

target for therapeutic intervention. CNTN2 has been shown to interact with CNTNAP2 and NFYB. GRCh38: Ensembl release 89: ENSG00000184144 – Ensembl, May 2017...

BTC; C1S; CASPR4; CD248; CD93; CELSR1; CELSR2; CELSR3; CLEC14A; CNTNAP1; CNTNAP2; CNTNAP3; CNTNAP4; CNTNAP5; COMP; COX-2; CRB1; CRB2; CSPG3; CUBN; DLK1;...

Hua; Ju, Kang; Wen, Zujia; Fu, Yingchun; An, Zhiguo; Zhao, Qian (2013). "CNTNAP2 is significantly associated with schizophrenia and major depression in...

of; 304100; L1CAM Cortical dysplasia-focal epilepsy syndrome; 610042; CNTNAP2 Corticosteroid-binding globulin deficiency; 611489; CBG Cortisone reductase...

the gene CNTNAP2 is specifically enriched for in the prefrontal cortex. The mouse homolog of CNTNAP2 is not expressed in the mouse brain. CNTNAP2 has been...

can be several hundred thousands bases long), for example genes RBFOX1, CNTNAP2, PTPRD and DLG2. Senapathy has provided a plausible answer to these questions...