• Thumbnail for Interleukin 8 receptor, beta
    Interleukin 8 receptor, beta is a chemokine receptor. IL8RB is also known as CXCR2, and CXCR2 is now the IUPHAR Committee on Receptor Nomenclature and Drug...
    12 KB (1,472 words) - 03:52, 10 March 2024
  • Thumbnail for CXCL1
    both monomer and dimer and both forms are able to bind chemokine receptor CXCR2. However, CXCL1 chemokine is able to dimerize only at higher (micromolar)...
    14 KB (1,728 words) - 18:04, 16 April 2024
  • CXC chemokine receptors in mammals, named CXCR1 through CXCR6. CXCR1 and CXCR2 are closely related receptors that recognize CXC chemokines that possess...
    9 KB (885 words) - 07:16, 30 April 2024
  • Thumbnail for Interleukin 8
    serpentine receptors CXCR1 and CXCR2. Expression and affinity for IL-8 differs between the two receptors (CXCR1 > CXCR2). Through a chain of biochemical...
    22 KB (2,786 words) - 02:02, 19 August 2024
  • Thumbnail for Chemokine
    express several receptors for chemokines: CCR1, CCR2, CCR3, CCR4, CCR5, CXCR2, and CXCR4. Ligands of these receptors CCL2 and CCL5 play an important role...
    30 KB (2,931 words) - 10:43, 29 July 2024
  • chemokines (CXCL1-3 and CXCL5-8), thereby limiting signaling through CXCR1 and CXCR2". It was tested in clinical trials for hidradenitis suppurativa. Fragoso...
    4 KB (223 words) - 23:47, 17 July 2024
  • Thumbnail for CXCL2
    mobilizes cells by interacting with a cell surface chemokine receptor called CXCR2. CXCL2, like related chemokines, is also a powerful neutrophil chemoattractant...
    6 KB (661 words) - 15:28, 27 April 2024
  • Thumbnail for CXCL6
    chemotactic effects by interacting with the chemokine receptors CXCR1 and CXCR2. The gene for CXCL6 is located on human chromosome 4 in a cluster with other...
    2 KB (285 words) - 03:28, 28 October 2022
  • serpentine receptors CXCR1 and CXCR2. Expression and affinity for IL-8 differs between the two receptors (CXCR1 > CXCR2). Through a chain of biochemical...
    45 KB (4,194 words) - 12:36, 2 May 2024
  • Thumbnail for Dupilumab
    Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab...
    22 KB (1,789 words) - 04:29, 16 July 2024
  • Thumbnail for Signal transduction
    encoding the chemokine receptor CXCR2; mutated cells underwent a malignant transformation due to the expression of CXCR2 in an active conformation despite...
    63 KB (7,609 words) - 04:41, 21 June 2024
  • Thumbnail for Ubiquitin
    (CXCL8, GCP-1) Antagonists: Navarixin NAMs: Ladarixin Reparixin (repertaxin) CXCR2 (IL-8Rβ) Agonists: CXCL1 (MGSA) CXCL2 CXCL3 CXCL5 CXCL6 CXCL7 Emoctakin...
    98 KB (11,068 words) - 18:53, 17 August 2024
  • Thumbnail for CXCL5
    elicits these effects by interacting with the cell surface chemokine receptor CXCR2. The gene for CXCL5 has four exons and is located on human chromosome 4...
    12 KB (1,445 words) - 20:42, 26 March 2024
  • Thumbnail for CD4
    Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab...
    22 KB (2,581 words) - 20:03, 21 June 2024
  • Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab...
    34 KB (2,656 words) - 17:19, 28 August 2024
  • Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab...
    14 KB (1,037 words) - 04:45, 6 July 2024
  • Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab...
    14 KB (1,147 words) - 07:33, 11 August 2024
  • Thumbnail for Conolidine
    (CXCL8, GCP-1) Antagonists: Navarixin NAMs: Ladarixin Reparixin (repertaxin) CXCR2 (IL-8Rβ) Agonists: CXCL1 (MGSA) CXCL2 CXCL3 CXCL5 CXCL6 CXCL7 Emoctakin...
    10 KB (962 words) - 22:42, 28 August 2024
  • Thumbnail for Secukinumab
    Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab...
    17 KB (1,245 words) - 14:04, 2 September 2024
  • Thumbnail for Cellular senescence
    MV, Augert A, Raguz S, et al. (June 2008). "Chemokine signaling via the CXCR2 receptor reinforces senescence". Cell. 133 (6): 1006–1018. doi:10.1016/j...
    58 KB (6,427 words) - 19:31, 11 July 2024
  • Thumbnail for Anakinra
    Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab...
    24 KB (2,070 words) - 07:13, 15 March 2024
  • Thumbnail for CCR5
    / CCRL1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1...
    67 KB (7,852 words) - 18:22, 10 September 2024
  • Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab...
    43 KB (3,661 words) - 19:54, 27 August 2024
  • Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab...
    16 KB (1,451 words) - 18:24, 2 August 2024
  • Thumbnail for Interleukin 10
    Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab...
    40 KB (4,619 words) - 05:18, 22 August 2024
  • Thumbnail for Cytokine receptor
    / CCRL1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1...
    6 KB (442 words) - 05:35, 18 May 2024
  • Thumbnail for Allergic bronchopulmonary aspergillosis
    by numerous inflammatory cytokines and neutrophilic attractants (such as CXCR2 receptor ligands). In this situation, mucociliary clearance is initiated...
    37 KB (3,822 words) - 03:50, 8 September 2024
  • Thumbnail for Interleukin 2
    Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab...
    43 KB (5,000 words) - 13:28, 1 July 2024
  • Thumbnail for TNF receptor superfamily
    / CCRL1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1...
    8 KB (501 words) - 13:55, 10 September 2024
  • Thumbnail for Platelet factor 4
    (CXCL8, GCP-1) Antagonists: Navarixin NAMs: Ladarixin Reparixin (repertaxin) CXCR2 (IL-8Rβ) Agonists: CXCL1 (MGSA) CXCL2 CXCL3 CXCL5 CXCL6 CXCL7 Emoctakin...
    14 KB (1,641 words) - 23:08, 5 September 2024