• Cdc14 and Cdc14 are a gene and its protein product respectively. Cdc14 is found in most of the eukaryotes. Cdc14 was defined by Hartwell in his famous...
    24 KB (2,752 words) - 23:54, 25 August 2023
  • Thumbnail for Telophase
    redundant phosphatases for mitotic exit and rely on the phosphatase cdc14. Blocking cdc14 activation in these cells results in the same phenotypic arrest...
    22 KB (2,667 words) - 12:46, 17 May 2024
  • (Figure 2). To initiate the onset of anaphase, securin is dephosphorylated by Cdc14 and other phosphatases. Dephosphorylated securin is recognized by the Anaphase-Promoting...
    5 KB (562 words) - 22:08, 12 July 2024
  • role and substrate specificity of PRLs is poorly known. Cdc14 phosphatases: The four mammalian Cdc14 proteins (named KAP, Cdc14A, Cdc14B and PTP9Q22) play...
    4 KB (533 words) - 20:19, 11 November 2023
  • mitotic exit by promoting release of Cdc14 from nucleolus. At later phase, downregulation of Cdk1 and activation of Cdc14, a Cdh1-activating phosphatase, promotes...
    50 KB (6,678 words) - 21:54, 13 July 2024
  • Thumbnail for Angelika Amon
    division. Her Whitehead team identified an interaction between phosphatase and CDC14 which initiates the exit of cells from mitosis to the G1 phase. Amon's team...
    25 KB (2,312 words) - 15:58, 11 April 2024
  • mitotic exit by promoting release of Cdc14 from nucleolus. At later phase, downregulation of Cdk1 and activation of Cdc14, a Cdh1-activating phosphatase, promotes...
    27 KB (3,400 words) - 21:54, 13 July 2024
  • Thumbnail for APC/C activator protein CDH1
    phosphorylated by CDKs, which inactivates it and it can be dephosphorylated by Cdc14. In the dephosphorylated form it can interact with APC/c and build the active...
    14 KB (1,553 words) - 03:55, 26 August 2024
  • Thumbnail for Separase
    the sister chromatids. Separase initiates the activation of Cdc14 in early anaphase and Cdc14 has been found to dephosphorylate securin, thereby increasing...
    10 KB (1,199 words) - 03:08, 12 April 2024
  • Thumbnail for Chitinase
    with other networks controlling the different phases of the cell, such as Cdc14 Early Anaphase Release (FEAR), mitotic exit network (MEN), and regulation...
    29 KB (3,192 words) - 04:19, 27 May 2024
  • Thumbnail for P53
    PMC 1223307. PMID 12534345. Li L, Ljungman M, Dixon JE (January 2000). "The human Cdc14 phosphatases interact with and dephosphorylate the tumor suppressor protein...
    124 KB (13,220 words) - 11:01, 30 August 2024
  • exit from mitosis is governed by the release of the protein phosphatase Cdc14 from its nucleolar anchor protein Net1 in late anaphase, which is triggered...
    18 KB (2,482 words) - 05:06, 15 February 2024
  • Thumbnail for CDC14B
    phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and...
    7 KB (827 words) - 16:34, 13 October 2024
  • cannot be expressed. SIR2 forms a complex with NET1 (a nuclear protein) and CDC14 (a phosphatase) to form the regulator of nucleolar silencing and telophase...
    19 KB (2,343 words) - 01:04, 3 December 2023
  • Thumbnail for Frank Uhlmann
    well as cleaving cohesin, separase promotes mitotic exit by activating the Cdc14 phosphatase in a protease-independent manner. In 2006, Uhlmann was also...
    11 KB (833 words) - 20:09, 3 December 2023
  • Thumbnail for CDC14A
    phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and...
    8 KB (997 words) - 16:34, 13 October 2024