Chaperone-mediated autophagy (CMA) refers to the chaperone-dependent selection of soluble cytosolic proteins that are then targeted to lysosomes and directly...

microautophagy, chaperone-mediated autophagy (CMA), and crinophagy. In macroautophagy (the most thoroughly researched form of autophagy), cytoplasmic components...

Pharmacological chaperone, a molecule which stabilizes protein folding, used in treatment for loss of function Chaperone-mediated autophagy, a selective...

of autophagic pathway, but unlike macroautophagy and chaperone-mediated autophagy, it is mediated—in mammals by lysosomal action or in plants and fungi...

localize to the cytoplasm and lysosome, where it participates in chaperone-mediated autophagy by aiding the unfolding and translocation of substrate proteins...

- LAMP-2A, LAMP-2B and LAMP-2C. LAMP-2A is the receptor for chaperone-mediated autophagy. Recently it has been determined that antibodies against LAMP-2...

molecules. Generally, autophagy includes three small branches, which are macroautophagy, microautophagy, and chaperone-mediated autophagy. Most organisms that...

protein LAMP2A as the receptor for this form of autophagy and termed it chaperone-mediated autophagy. In October 2001, Cuervo accepted a faculty position...

clearance from dendrites by mitophagy. LRRK2 is also a substrate for chaperone-mediated autophagy. Mutations in this gene have been associated with Parkinson's...

substrate. This can be split into two forms of autophagy: macroautophagy and chaperone-mediated autophagy (CMA). macroautophagy is involved with nutrient...

Chaperone-assisted selective autophagy is a cellular process for the selective, ubiquitin-dependent degradation of chaperone-bound proteins in lysosomes...

work by molecular chaperones is not enough to prevent incorrect folding, the protein may be degraded by the proteasome or autophagy to remove any potentially...

afterwards. They are also involved in a special type of autophagy called chaperone-mediated autophagy, when they enable cytosolic proteins to get into lysosomes...

lysosomal membrane to enclose the cytosol or organelles. The chaperone-mediated autophagy (CMA) protein quality assurance by digesting oxidized and altered...

lysosome-associated membrane protein 2a (LAMP2a) to help initiate chaperone-mediated autophagy, whereby a heat shock protein 70kDa protein 8 (HSPA8)-containing...

QX39 (Compound A, CA39) is a synthetic compound that activates chaperone-mediated autophagy (CMA) by increasing the expression of the lysosomal receptor...

CA77.1 (CA) is a synthetic compound that activates chaperone-mediated autophagy (CMA) by increasing the expression of the lysosomal receptor for this pathway...

Australia, former name of the Australian Multicultural Council Chaperone-mediated autophagy Calcium magnesium acetate, an inorganic compound Chloromethamphetamine...

Cuervo AM, Dice JF (October 2000). "Age-related decline in chaperone-mediated autophagy". The Journal of Biological Chemistry. 275 (40): 31505–31513...

curli exposure. Studies in biochemistry show that endogenous, bacterial chaperones of curli are capable of briefly interacting with Syn and controlling its...

of Parkinson's disease could be due to an interference with a chaperone-mediated autophagy caused by the protein alpha-synuclein. His work indicates that...

by pinocytosis, macroautophagy, endosomal microautophagy or chaperone-mediated autophagy. In the first case, after internalisation, the antigens are enclosed...

Autophagy related 7 is a protein in humans encoded by ATG7 gene. Related to GSA7; APG7L; APG7-LIKE. ATG 7, present in both plant and animal genomes, acts...

LJ, Höhfeld J, Patterson C (Jan 2001). "The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins". Nature Cell Biology....

activity has been implicated in the regulation of autophagy(macroautophagy and chaperone-mediated autophagy). In addition, mTORC2 has tyrosine kinase activity...

glial cell proliferation long-term potentiation regulation of chaperone-mediated autophagy intermediate filament organization Sources:Amigo / QuickGO...

atherosclerotic plaque formation, and heart attack. Humanin activates chaperone-mediated autophagy in a dose-dependent manner. Humanin decreases production of inflammatory...

and an actin bundling protein. As an elongation factor, it is known to mediate the recruitment of aminoacyl-tRNA to the A-site of the 80S ribosome during...

mechanisms for maintaining proteostasis include regulated protein translation, chaperone assisted protein folding, and protein degradation pathways. Adjusting...

molecular chaperone regulator 3 is a protein that in humans is encoded by the BAG3 gene. BAG3 is involved in chaperone-assisted selective autophagy. BAG proteins...