The cholinergic anti-inflammatory pathway regulates the innate immune response to injury, pathogens, and tissue ischemia. It is the efferent, or motor...

signaling pathways by binding to α-7 nicotinic receptors on macrophage or neurons, hence activating the cholinergic anti-inflammatory pathway. Changes...

inflammation. Signaling in the efferent arc of the inflammatory reflex, termed the "Cholinergic anti-inflammatory pathway," provides a regulatory check on the innate...

and possibly having systemic effects. Additionally, the cholinergic anti-inflammatory pathway, signaling through the vagus nerve, affects the gut epithelium...

cytokine-producing cells. The motor arc of the inflammatory reflex is termed the cholinergic anti-inflammatory pathway. The parts of the innate immune system...

activity Prefrontally modulated and vagally mediated cholinergic input to the spleen reduces inflammatory responses Glutamate agonists, cytokine inhibitors...

Vagus Nerve Stimulation (VNS) is used to activate the Cholinergic Anti-inflammatory Pathway (CAP) in the vagus nerve, ending in reduced inflammation...

ghrelin also activates the cholinergic–dopaminergic reward link in inputs to the ventral tegmental area and in the mesolimbic pathway, a circuit that communicates...

zafirlukast, inhibit pro-inflammatory leukotrienes bindings to LTC4 and LTD4 receptors. This blocks the downstream inflammatory pathways that lead to bronchospasm...

Chemokine Chemokine receptor Chimeric antigen receptor Cholinergic anti-inflammatory pathway CLIP (protein) Clonal anergy Clonal deletion Clonal selection...

vagus nerve in regulating systemic inflammation via the Cholinergic Anti-inflammatory Pathway. The neuroimmune system is involved in reflexes associated...

"2007 Stetten Lecture – Physiology and Immunology of the Cholinergic Anti-inflammatory Pathway". NIH National Institute of General Medical Sciences. Retrieved...

eventually to the fetus, hindering normal neurogenesis. Cholinergic Anti-inflammatory Pathway (CAP). It is suspected that the virus disrupts CAP in suppressing...

Gallowitsch-Puerta M, Tracey KJ (2005). "Immunologic role of the cholinergic anti-inflammatory pathway and the nicotinic acetylcholine alpha 7 receptor". Ann....

irritation can lead to increased mucus production as a result of pro-inflammatory pathways, producing symptoms of PND. The exact mechanism of PND depends on...

nerve, thereby down-regulating inflammatory pathways via the recently discovered cholinergic anti-inflammatory pathway. In a preclinical study in rats...

pathways include interference with calcium ion channels, or inducing cell death pathways like MAPK and Notch signaling pathway. The anti-inflammatory...

effective to complement standardized treatment of acne due to their anti-inflammatory properties and their ability to suppress sebum production. H1-antihistamines...

have anti-inflammatory and neuroprotective effects, and to improve cognitive function. A recent study investigated the cholinergic anti-inflammatory pathway...

career, Pepeu's activity shifted to exploring the role of central cholinergic pathways in the pathophysiology of Alzheimer's disease, where he revealed...

"Cardiopulmonary arrest and resuscitation disrupts cholinergic anti-inflammatory processes: a role for cholinergic α7 nicotinic receptors". The Journal of Neuroscience...

Gilboa-Geffen A, et al. (2009). "MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase". Immunity. 31 (6):...

response of its target cell. A key signaling pathway that is activated by type II IFN is the JAK-STAT signaling pathway. IFNG plays an important role in both...

lipoteichoic acid, muramyl dipeptide and lipid A. They are also stimulated by cholinergic signaling normally preceding the arrival of food which potentially may...

Apo-E qualifies as a checkpoint inhibitor of the classical complement pathway by complex formation with activated C1q. Apolipoproteins are not unique...

the striatum are evident. Use of certain drugs (e.g., cocaine) affect cholinergic neurons that innervate the reward system, in turn affecting dopamine...

common side effect of these medications. Muscarinic antagonists (anti-cholinergics): Blocking the muscarinic acetylcholine receptors in pulmonary smooth...

gastrointestinal bleeding, particularly in individuals using nonsteroidal anti-inflammatory drugs (NSAIDs) or who have a history of peptic ulcer disease. Rivastigmine...

(5-aminosalicylic acid) in the treatment of IBS. Mesalazine is a drug with anti-inflammatory properties that has been reported to significantly reduce immune mediated...

that cyclobuxine has an anti-inflammatory activity, by reducing prostaglandin production and leukocyte migration (in inflammatory exudates, both in vitro...