• Clathrin adaptor proteins, also known as adaptins, are vesicular transport adaptor proteins associated with clathrin. The association between adaptins...
    7 KB (799 words) - 14:20, 8 November 2024
  • Thumbnail for Clathrin
    Clathrin is a protein that plays a role in the formation of coated vesicles. Clathrin was first isolated by Barbara Pearse in 1976. It forms a triskelion...
    22 KB (2,093 words) - 02:41, 12 November 2024
  • Adaptor protein may refer to: Signal transducing adaptor protein Vesicular transport adaptor protein Clathrin adaptor protein, also known as adaptin This...
    184 bytes (52 words) - 02:14, 11 July 2017
  • Thumbnail for Vesicular transport adaptor protein
    Vesicular transport adaptor proteins are proteins involved in forming complexes that function in the trafficking of molecules from one subcellular location...
    21 KB (2,331 words) - 09:27, 5 October 2024
  • Thumbnail for AP2S1
    complex subunit sigma is a protein that in humans is encoded by the AP2S1 gene. One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer...
    6 KB (783 words) - 15:35, 29 September 2022
  • Thumbnail for Vesicular transport protein
    Archain ARFs Clathrin Caveolin Dynamin and related proteins, such as the EHD protein family Rab proteins SNAREs Vesicular transport adaptor proteins e.g. Sorting...
    2 KB (170 words) - 18:17, 14 February 2022
  • Thumbnail for Adaptor-related protein complex 2, alpha 1
    et al. (1997). "Association and colocalization of Eps15 with adaptor protein-2 and clathrin". J. Cell Biol. 136 (4): 811–21. doi:10.1083/jcb.136.4.811....
    8 KB (977 words) - 15:01, 16 August 2023
  • Thumbnail for G protein-coupled receptor
    to serve as a scaffolding protein for an adaptor complex termed AP-2, which in turn recruits another protein called clathrin. If enough receptors in the...
    82 KB (9,384 words) - 16:34, 5 September 2024
  • Ap180 (category Peripheral membrane proteins)
    AP180 is a protein that plays an important role in clathrin-mediated endocytosis of synaptic vesicles. It is capable of simultaneously binding both membrane...
    3 KB (403 words) - 21:38, 24 October 2023
  • Thumbnail for AP2 adaptor complex
    The AP2 adaptor complex is a multimeric protein that works on the cell membrane to internalize cargo in clathrin-mediated endocytosis. It is a stable complex...
    11 KB (1,387 words) - 07:30, 15 November 2023
  • Thumbnail for Adaptor complexes medium subunit domain
    the adaptor complexes medium subunit domain is a protein domain found at the C-terminus of the mu subunit from various clathrin adaptor protein complexes...
    3 KB (339 words) - 19:21, 21 December 2022
  • Thumbnail for Receptor-mediated endocytosis
    plasma membrane. The ligand and receptor will then recruit adaptor proteins and clathrin triskelions to the plasma membrane around where invagination...
    10 KB (1,096 words) - 11:02, 3 December 2023
  • Clathrin adaptor proteins, also known as adaptins, are proteins that mediate the formation of vesicles for intracellular trafficking and secretion. Adaptins...
    3 KB (268 words) - 19:45, 9 February 2024
  • Thumbnail for Low-density lipoprotein receptor adapter protein 1
    Cohen Jonathan C (Nov 2002). "ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2". J. Biol. Chem. 277 (46). United...
    9 KB (1,118 words) - 09:21, 24 December 2023
  • Thumbnail for AP1B1
    AP-1 complex subunit beta-1 is a protein that in humans is encoded by the AP1B1 gene. Adaptor protein complex 1 is found at the cytoplasmic face of coated...
    9 KB (1,138 words) - 00:14, 5 October 2022
  • Thumbnail for Endocytosis
    cytosolic protein clathrin. Clathrin-coated vesicles (CCVs) are found in virtually all cells and form domains of the plasma membrane termed clathrin-coated...
    25 KB (2,981 words) - 01:09, 18 October 2024
  • Thumbnail for SNARE protein
    an adaptor protein, alpha-SNAP. Then, the hexameric ATPase (of the AAA type) called NSF catalyzes the ATP-dependent unfolding of the SNARE proteins and...
    53 KB (6,592 words) - 21:23, 11 November 2024
  • AP1 or AP-1 may refer to: Activator protein 1, dimeric transcription factor Adaptor protein 1, tetrameric clathrin-associated complex Autopista AP-1, a...
    535 bytes (99 words) - 06:12, 19 December 2022
  • Thumbnail for Huntingtin-interacting protein 1
    and a novel HIP1 protein interactor HIPPI. HIP1’s non-pathological activity includes clathrin assembly via interaction with clathrin light chains. HIP1...
    6 KB (871 words) - 23:51, 3 March 2023
  • Coatomer (category Peripheral membrane proteins)
    Coatomers are functionally analogous and evolutionarily homologous to clathrin adaptor proteins, also known as adaptins, which regulate endocytosis from the plasma...
    11 KB (1,270 words) - 17:05, 29 September 2024
  • Thumbnail for DAB2
    "Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor". EMBO J. 21 (18): 4915–26. doi:10.1093/emboj/cdf487. PMC 126284. PMID 12234931...
    11 KB (1,389 words) - 19:32, 13 August 2023
  • Thumbnail for AAK1
    been determined. Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact...
    7 KB (793 words) - 14:51, 24 May 2024
  • Thumbnail for COPI
    COPI (category Protein pages needing a picture)
    ARF-dependent adaptors. COPI consists of seven subunits which compose the heteroheptameric protein complex. The primary function of adaptors is the selection...
    11 KB (1,337 words) - 08:31, 15 January 2024
  • proteins; investigating how clathrin and adaptors are hijacked by the HIV-1-encoded protein Nef; determine why mutations in the non-clathrin adaptors...
    15 KB (1,587 words) - 12:45, 19 October 2024
  • Thumbnail for Valosin-containing protein
    "Chromosome localization of human genes for clathrin adaptor polypeptides AP2 beta and AP50 and the clathrin-binding protein, VCP". Genomics. 30 (1): 94–7. doi:10...
    49 KB (5,868 words) - 06:02, 3 June 2024
  • Thumbnail for AP1G1
    AP1G1 (category Proteins)
    an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and...
    12 KB (1,457 words) - 14:08, 27 March 2022
  • Thumbnail for AP4M1
    Mullins C, Bonifacino JS (Apr 1999). "AP-4, a novel protein complex related to clathrin adaptors". J Biol Chem. 274 (11): 7278–85. doi:10.1074/jbc.274...
    6 KB (680 words) - 08:48, 10 January 2024
  • Thumbnail for AP3M1
    mu-1 is a protein that in humans is encoded by the AP3M1 gene. The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related...
    7 KB (860 words) - 09:17, 25 August 2024
  • Thumbnail for Receptor tyrosine kinase
    Other proteins that interact with the activated receptor act as adaptor proteins and have no intrinsic enzymatic activity of their own. These adaptor proteins...
    28 KB (3,078 words) - 07:46, 3 June 2024
  • Thumbnail for CLTC
    Clathrin heavy chain 1 is a protein that in humans is encoded by the CLTC gene. Clathrin is a major protein component of the cytoplasmic face of intracellular...
    9 KB (1,087 words) - 07:29, 13 October 2024