Clopidogrel, sold under the brand name Plavix among others, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those...

whether clopidogrel is significantly influenced by such variants). Ticagrelor was found to result in a lower risk of stroke at 90 days than clopidogrel, which...

PCI. Prasugrel is associated with a higher bleeding risk compared to clopidogrel but has demonstrated superiority in reducing the composite endpoint of...

clopidogrel to prevent these events. This interaction is possible because omeprazole is an inhibitor of the enzymes CYP2C19 and CYP3A4. Clopidogrel is...

drugs in current clinical use, most notably the antiplatelet treatment clopidogrel (Plavix), drugs that treat pain associated with ulcers, such as omeprazole...

ticlopidine but due to adverse effects it is not much used today. Ticlopidine, clopidogrel and prasugrel (Efient) are all thienopyridines that cause irreversible...

therapy. Often a combination of aspirin plus an ADP/P2Y inhibitor (such as clopidogrel, prasugrel, ticagrelor, or another) is used to obtain greater effectiveness...

desirable. With the advent of newer and safer antiplatelet drugs such as clopidogrel and ticagrelor, its use remained limited. It was patented in 1973 and...

increase if they are used concomitantly with esomeprazole. Conversely, clopidogrel (Plavix) is an inactive prodrug that partially depends on CYP2C19 for...

extended-release dipyridamole, or clopidogrel alone. Clopidogrel and aspirin have similar efficacies and side effect profiles. Clopidogrel is more expensive and has...

antiplatelet therapy (DAPT) which consists of a P2Y12 inhibitor, such as clopidogrel, which is taken at the same time as acetylsalicylic acid (aspirin). Dual...

Frequently, aspirin is combined with an ADP receptor inhibitor, such as clopidogrel, prasugrel, or ticagrelor to prevent blood clots. This is called dual...

expensive. Both aspirin and clopidogrel may be useful in the first few weeks after a minor stroke or high-risk TIA. Clopidogrel has less side effects than...

continued indefinitely, as well as another antiplatelet agent such as clopidogrel or ticagrelor ("dual antiplatelet therapy" or DAPT) for up to twelve...

repaglinide and may lead to hypoglycemia. Co-administration of repaglinide and clopidogrel (a CYP2C8 inhibitor) may lead to a significant decrease in blood glucose...

time. The risk of bleeding increases with the concurrent medications clopidogrel, cefoperazone, valproic acid, cefotetan, eptifibatide, tirofiban, and...

adenosine diphosphate-mediated platelet activation and aggregation. Unlike clopidogrel (Plavix), which is a prodrug, cangrelor is an active drug not requiring...

BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel (AXIOMATIC-SSP)". ClinicalTrial.gov. U.S. National Library of Medicine...

medications that are affected include bisphosphonate derivatives, fluconazole, clopidogrel, and methotrexate. The mechanism of action of pantoprazole is to inhibit...

AR-C 67085MX AR-C 69931MX AR-C 118925XX ATP BzATP C1330-7 Cangrelor Clopidogrel Elinogrel Ip5I MRS-2179 MRS-2211 MRS-2279 MRS-2395 MRS-2500 MRS-2578...

risk may still find the potential benefits worth the associated risks. Clopidogrel plus aspirin (dual anti-platelet therapy) reduces cardiovascular events...

interaction between PPIs and the metabolism of the platelet inhibitor clopidogrel is known and this drug is also often used in people with cardiac disease...

that G6PD deficiency could reduce the antiplatelet efficacy of clopidogrel (clopidogrel resistance). G6PD deficiency is the second most common human enzyme...

AR-C 67085MX AR-C 69931MX AR-C 118925XX ATP BzATP C1330-7 Cangrelor Clopidogrel Elinogrel Ip5I MRS-2179 MRS-2211 MRS-2279 MRS-2395 MRS-2500 MRS-2578...

older anticoagulants (e.g., warfarin) and antiplatelet agents (e.g., clopidogrel, ticlopidine, prasugrel, ticagrelor, and/or aspirin) should not be altered...

risks in the deal for both sides was the fate of the patents protecting Clopidogrel (Plavix), which was one of the top-selling drugs in the world at the...

patients presenting after cerebral ischemia. A triple therapy of aspirin, clopidogrel, and dipyridamole has been investigated, but this combination led to...

of the heart's muscle cells. Antiplatelet drugs such as aspirin and clopidogrel can reduce platelet aggregation at the unstable atherosclerotic plaque...

Coumadin (warfarin) Eliquis (apixaban) – comarketed with Pfizer Plavix (clopidogrel) – comarketed with Sanofi Pravachol (pravastatin) Diabetes mellitus Bydureon...

a precursor to several drugs, including tipepidine, ticlopidine, and clopidogrel. The LD50 is low, 200 – 250 mg/kg (oral, rat). Jonathan Swanston (2006)...