• Cmax is the maximum (or peak) serum concentration that a drug achieves in a specified compartment or test area of the body after the drug has been administered...
    4 KB (345 words) - 16:17, 26 September 2024
  • Cmax may refer to: Customatix, a footwear company C Max, a maximum security prison in South Africa Ford C-MAX, a model of car Cmax (pharmacology), the...
    423 bytes (92 words) - 14:14, 2 September 2020
  • which combines pharmacokinetics and pharmacodynamics. Cmax (pharmacology) Cmean (pharmacology) "Area Under Curve" of the Receiver operating characteristic...
    11 KB (1,271 words) - 08:43, 18 August 2023
  • In pharmacology, bioavailability is a subcategory of absorption and is the fraction (%) of an administered drug that reaches the systemic circulation....
    22 KB (2,749 words) - 05:48, 14 April 2024
  • Thumbnail for Cetirizine
    to decrease the Cmax by 23%. Similar findings were reported for levocetirizine, which had its Tmax delayed by 1.25 hours and its Cmax decreased by about...
    36 KB (3,347 words) - 11:03, 24 September 2024
  • insomnia. Since there are limited clinical trials and human studies, the pharmacology and drug effects of most of the synthetic drugs are not well-known. Misuse...
    25 KB (2,877 words) - 22:38, 8 December 2023
  • Cavg (redirect from Cavg (pharmacology))
    {\text{ss}}}} is the area under the curve and τ {\displaystyle \tau } the dosing interval. Area under the curve (pharmacokinetics) Cmax (pharmacology) v t e...
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  • Thumbnail for Racecadotril
    rapidly absorbed after oral administration and reaches Cmax within 60 minutes. Food delays Cmax by 60 to 90 minutes but does not affect the overall bioavailability...
    12 KB (920 words) - 20:04, 15 September 2024
  • order to avoid overdosing. A trough level is contrasted with a "peak level" (Cmax), which is the highest level of the medicine in the body, and the "average...
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  • Thumbnail for Eluxadoline
    concentrations tested (400 ng/ml, which is 162-fold larger than the observed Cmax of the highest therapeutic dose of 100 mg). However, it was not to be transported...
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  • Thumbnail for Peak-to-trough ratio
    fluctuation, is a parameter in pharmacokinetics which is defined as the ratio of Cmax (peak) concentration and Cmin (trough) concentration over a dosing interval...
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  • Thumbnail for Prucalopride
    significant differences compared with placebo. Prucalopride is rapidly absorbed (Cmax attained 2–3 hours after single 2 mg oral dose) and is extensively distributed...
    20 KB (1,928 words) - 10:37, 20 September 2024
  • Thumbnail for Atorvastatin
    a four-fold increase in both Cmax and AUC. People with Child Pugh stage B liver disease show a 16-fold increase in Cmax and an 11-fold increase in AUC...
    100 KB (9,451 words) - 00:33, 30 September 2024
  • Thumbnail for Methylphenidate
    on the observed Cmax differ between some extended-release formulations, with combined IR/ER and OROS formulations showing reduced Cmax levels while liquid-based...
    149 KB (13,773 words) - 03:18, 28 September 2024
  • Thumbnail for Paracetamol
    concentration (Cmax), and increase Cmax. Medications slowing gastric emptying such as propantheline and morphine lengthen tmax and decrease Cmax. The interaction...
    123 KB (12,218 words) - 03:41, 30 September 2024
  • Thumbnail for Biological half-life
    (such as a medication) to decrease from its maximum concentration (Cmax) to half of Cmax in the blood plasma. It is denoted by the abbreviation t 1 2 {\displaystyle...
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  • Thumbnail for Hydroxybupropion
    "hydroxylation of the tert-butyl group" by CYP2B6 and is excreted renally. Cmax values of hydroxybupropion are 4–7 times that of bupropion, while the exposure...
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  • concentration-derived parameters such as AUC (area under the concentration curve) and Cmax (peak level of the concentration curve) of the drug after its administration[citation...
    23 KB (2,754 words) - 20:25, 30 September 2024
  • Thumbnail for Dapoxetine
    concentration (Cmax) is reached one to two hours after oral administration. The Cmax and AUC (area under the plasma vs. time curve) is dose dependent. The Cmax and...
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  • Thumbnail for Spironolactone
    Deinum J, Riksen NP, Lenders JW (October 2015). "Pharmacological treatment of aldosterone excess". Pharmacology & Therapeutics. 154: 120–33. doi:10.1016/j.pharmthera...
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  • Thumbnail for Monepantel
    Tmax was 8 hours, Cmax 21.5 ng/mL and AUC 2174 ng.h/mL while the major metabolite monepantel sulphone had a Tmax of 41.3 hours, Cmax of 96.8 ng/mL and...
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  • elimination half-life, bioavailability, protein binding, the blood concentration Cmax at time tmax, and other pharmacokinetic parameters of various medications...
    44 KB (4,559 words) - 22:03, 7 July 2024
  • Thumbnail for Ezetimibe
    to fasting adults, the attained mean ezetimibe peak plasma concentration (Cmax) was 3.4–5.5 ng/ml. Following oral administration, ezetimibe is absorbed...
    20 KB (1,874 words) - 21:27, 21 September 2024
  • Thumbnail for Tapentadol
    salts includes 0.86 for the hydrochloride. The peak plasma concentration (Cmax; amount of active drug in the bloodstream) when taken after eating is increased...
    35 KB (3,372 words) - 20:43, 21 September 2024
  • Thumbnail for Gabapentin
    Food does not significantly affect the Tmax of gabapentin and increases the Cmax and area-under-curve levels of gabapentin by approximately 10%. Gabapentin...
    91 KB (8,927 words) - 17:50, 11 September 2024
  • Thumbnail for Metopimazine
    comparable between adults and children. The maximum plasma concentration (Cmax) of metopimazine is reached approximately 60 minutes after oral administration...
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  • Thumbnail for Budesonide
    plasma concentrations (Cmax) within 2–8 hours. A high fat meal when taken with the capsule can lengthen the time it takes to reach Cmax by another 2.3 hours...
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  • Thumbnail for Zopiclone
    humans are stereoselective. After oral administration of the racemic mixture, Cmax (time to maximum plasma concentration), area under the plasma time-concentration...
    54 KB (6,026 words) - 12:14, 19 August 2024
  • Thumbnail for Pharmacology of bicalutamide
    The pharmacology of bicalutamide is the study of the pharmacodynamic and pharmacokinetic properties of the nonsteroidal antiandrogen (NSAA) bicalutamide...
    185 KB (20,418 words) - 18:20, 23 September 2024
  • Thumbnail for Vilazodone
    absorbed with food and has a bioavailability of 72% under fed conditions. The Cmax increased between 147 and 160% and the AUC increased between 64 and 85% of...
    22 KB (1,721 words) - 05:27, 7 May 2024