• Thumbnail for Cyclic di-AMP
    Cyclic di-AMP (also called c-di-AMP and c-di-adenosine monophosphate) is a second messenger used in signal transduction in bacteria and archaea. It is...
    18 KB (2,035 words) - 09:25, 25 April 2024
  • Thumbnail for Cyclic nucleotide
    well-studied cyclic nucleotides are cyclic AMP (cAMP) and cyclic GMP (cGMP), while cyclic CMP (cCMP) and cyclic UMP (cUMP) are less understood. cAMP is 3’5’-cyclic...
    21 KB (2,416 words) - 10:27, 3 December 2023
  • produce the cyclic dinucleotide cGAMP. Cyclic GMP-AMP (cGAMP) is a cyclic dinucleotide (CDN) and the first to be found in metazoans. Other CDNs (c-di-GMP and...
    23 KB (2,886 words) - 00:57, 20 August 2024
  • Thumbnail for Cyclic di-GMP
    Cyclic di-GMP (also called cyclic diguanylate and c-di-GMP) is a second messenger used in signal transduction in a wide variety of bacteria. Cyclic di-GMP...
    9 KB (935 words) - 06:49, 3 March 2024
  • Thumbnail for CREB
    Subject Headings (MeSH) Drosophila Cyclic-AMP response element binding protein A - The Interactive Fly Drosophila Cyclic-AMP response element binding protein...
    19 KB (2,243 words) - 08:04, 13 April 2024
  • Thumbnail for YdaO/yuaA leader
    The YdaO/YuaA leader (now called the cyclic di-AMP riboswitch) is a conserved RNA structure found upstream of the ydaO and yuaA genes in Bacillus subtilis...
    3 KB (281 words) - 08:34, 26 September 2023
  • Thumbnail for Riboswitch
    (see also "cyclic di-GMP" below). cyclic di-AMP riboswitches (also called ydaO/yuaA) bind the signaling molecule cyclic di-AMP. cyclic di-GMP riboswitches...
    36 KB (3,891 words) - 23:57, 30 June 2024
  • Thumbnail for NLPC-P60 RNA motif
    that sense the signaling molecule cyclic di-AMP. However, no associated between the NLPC-P60 RNA motif and cyclic di-AMP has been established. Weinberg Z...
    2 KB (161 words) - 20:47, 7 December 2021
  • Thumbnail for Diadenylate cyclase
    cyclic di-3',5'-adenylate. This enzyme has diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP)...
    2 KB (171 words) - 13:48, 26 August 2023
  • Thumbnail for Stimulator of interferon genes
    monocyte migration. The activation of STING is likely to be mediated by cyclic di-AMP secreted by intracellular bacteria. STING may be an important molecule...
    23 KB (2,748 words) - 13:53, 21 January 2024
  • Thumbnail for Cyclic guanosine monophosphate–adenosine monophosphate
    Cyclic guanosine monophosphate–adenosine monophosphate (cyclic GMP-AMP, cGAMP) is the first cyclic di-nucleotide found in metazoa. In mammalian cells...
    7 KB (717 words) - 18:46, 19 February 2023
  • Thumbnail for Mutation
    compensatory mutations. Whole genome sequencing results revealed that when Cyclic-di-AMP phosphodiesterase (GdpP) was disrupted in this bacterium, it compensated...
    117 KB (13,924 words) - 09:15, 8 August 2024
  • Thumbnail for Nucleic acid quaternary structure
    cell This motif has been observed in flavin mononucleotide (FMN), cyclic di-AMP (c-di-AMP), and glycine. Riboswitches are said to show pseudoquaternary structure...
    16 KB (1,981 words) - 11:54, 25 October 2023
  • Thumbnail for Cyclic di-GMP-I riboswitch
    Cyclic di-GMP-I riboswitches are a class of riboswitch that specifically bind cyclic di-GMP, which is a second messenger that is used in a variety of...
    6 KB (574 words) - 23:59, 30 June 2024
  • Thumbnail for Adenosine
    energy carriers adenosine mono-, di-, and triphosphate, also known as AMP/ADP/ATP. Cyclic adenosine monophosphate (cAMP) is pervasive in signal transduction...
    32 KB (3,346 words) - 01:19, 26 August 2024
  • nucleotide cyclic AMP (cAMP): HCN1 channels have a more positive threshold for activation, faster activation kinetics, and a lower sensitivity to cAMP, while...
    14 KB (1,568 words) - 07:22, 3 July 2024
  • Thumbnail for Phosphodiester bond
    biomolecules, e.g. acyl carrier proteins, phospholipids and the cyclic forms of GMP and AMP (cGMP and cAMP). Phosphodiester bonds make up the backbones of DNA and...
    5 KB (581 words) - 01:37, 14 August 2024
  • Wikidata Q38211157. Rebecca M Corrigan; Angelika Gründling (1 July 2013). "Cyclic di-AMP: another second messenger enters the fray". Nature Reviews Microbiology...
    4 KB (499 words) - 01:13, 23 June 2024
  • Waters CM, Montgomery BL (2018). "Homeostasis of Second Messenger Cyclic-di-AMP Is Critical for Cyanobacterial Fitness and Acclimation to Abiotic Stress"...
    24 KB (2,051 words) - 10:56, 21 July 2024
  • Thumbnail for Cyclic nucleotide–gated ion channel
    function can be the result of a combination of the binding of cyclic nucleotides (cGMP and cAMP) and either a depolarization or a hyperpolarization event...
    39 KB (4,913 words) - 23:11, 11 January 2024
  • Thumbnail for Adenosine triphosphate
    unchanged, but the triphosphate is converted to di- and monophosphate, giving respectively the derivatives ADP and AMP. The three phosphoryl groups are labeled...
    49 KB (5,446 words) - 08:06, 23 August 2024
  • Thumbnail for Slime mold
    traveling waves of cyclic AMP. There is an amplification of cyclic AMP when they aggregate. Pre-stalk cells move toward cyclic AMP, but pre-spore cells...
    54 KB (5,528 words) - 03:06, 16 July 2024
  • Thumbnail for Phosphodiesterase inhibitor
    inactivation of the intracellular second messengers, cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) by the respective PDE...
    22 KB (2,350 words) - 08:18, 3 June 2024
  • Thumbnail for Pseudomonas aeruginosa
    single molecule: cyclic di-GMP. At low cyclic di-GMP concentration, P. aeruginosa has a free-swimming mode of life. But when cyclic di-GMP levels increase...
    92 KB (10,021 words) - 13:15, 15 August 2024
  • Dr. Portnoy and collaborators have shown that immune cells recognize cyclic di-AMP, a novel and essential bacterial signaling molecule, secreted by L....
    12 KB (1,296 words) - 23:10, 26 March 2024
  • Thumbnail for Nucleotide
    nucleotides participate in cell signaling (cyclic guanosine monophosphate or cGMP and cyclic adenosine monophosphate or cAMP) and are incorporated into important...
    32 KB (3,305 words) - 22:21, 6 May 2024
  • S2CID 6180447. DiFrancesco, D.; Tortora, P. (1991-05-09). "Direct activation of cardiac pacemaker channels by intracellular cyclic AMP". Nature. 351 (6322):...
    25 KB (2,620 words) - 10:56, 5 January 2024
  • characterized cyclic dinucleotide c-di-AMP as an allosteric regulator of metabolic enzyme function, chemical proteomics were used to define the c-di-AMP interactome...
    9 KB (962 words) - 04:25, 30 October 2023
  • Thumbnail for Cyclic ADP-ribose
    Cyclic ADP-ribose, frequently abbreviated as cADPR, is a cyclic adenine nucleotide (like cAMP) with two phosphate groups present on 5' OH of the adenosine...
    12 KB (1,183 words) - 14:06, 24 November 2023
  • 6 September 2023. DiFrancesco D, Tortora P (May 1991). "Direct activation of cardiac pacemaker channels by intracellular cyclic AMP". Nature. 351 (6322):...
    10 KB (1,195 words) - 21:33, 8 November 2023