A cytotoxic T cell (also known as TC, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8+ T-cell or killer T cell) is a T lymphocyte (a...
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growth of cytotoxic T cells, and in maximizing bactericidal activity of phagocytes such as macrophages and neutrophils. CD4+ cells are mature Th cells that...
54 KB (6,597 words) - 14:51, 21 July 2024
"killer T cells", are cytotoxic – this means that they are able to directly kill virus-infected cells, as well as cancer cells. CD8+ T cells are also...
71 KB (9,026 words) - 12:33, 26 April 2024
these cells: CD4+ TH1 cells CD8+ cytotoxic T cells (Tc1) T-Bet+ interferon gamma producing group 1 ILCs(ILC1 and Natural killer cells) CD4+ TH1 Cells It...
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and T cells. Antigen-presenting cells are vital for effective adaptive immune response, as the functioning of both cytotoxic and helper T cells is dependent...
16 KB (2,128 words) - 09:55, 4 March 2024
Natural killer cells, also known as NK cells, are a type of cytotoxic lymphocyte critical to the innate immune system. They are a kind of large granular...
75 KB (9,227 words) - 03:58, 24 August 2024
Cytotoxicity is the quality of being toxic to cells. Examples of toxic agents are toxic metals, toxic chemicals, microbe neurotoxins, radiation particles...
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the cytotoxic T cells (CD8-positive) subset, similar populations appear to exist for both the helper T cells (CD4-positive) and the cytotoxic T cells. Primary...
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blood T cells. Natural killer T cells should neither be confused with natural killer cells nor killer T cells (cytotoxic T cells). The term "NK T cells" was...
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antigen on a cell's surface, T cells bind to it and become activated, then proceed to proliferate and become cytotoxic. CAR T cells destroy cells through several...
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Gamma delta T cells (γδ T cells) are T cells that have a γδ T-cell receptor (TCR) on their surface. Most T cells are αβ (alpha beta) T cells with TCR composed...
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forms of helper T cells (CD4+) and cytotoxic T cells (CD8+). Any naive T cell is considered immature and, unlike activated or memory T cells, has not encountered...
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cytoskeletal remodeling resulting in T-cell activation. Active T cells secrete cytokines, undergo rapid proliferation, have cytotoxic activity and differentiate...
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DNA vaccine (section Cytotoxic T-cell responses)
helper and cytotoxic T-cells can control viral infections by secreting interferons. Cytotoxic T cells usually kill virally infected cells. However, they...
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into helper T cells, memory T cells, cytotoxic T cells), B cells (subdivided into plasma cells and memory B cells), and natural killer cells. Historically...
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Epstein–Barr virus–associated lymphoproliferative diseases (section EBV+ NK/T cell lymphoproliferative diseases)
delta T cells (γδ T cells), cytotoxic T cells (CTL), helper T cells (Th cells), and follicular B helper T cells (TFH cells). The means by which EBV establishes...
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CD8 (category T cells)
co-receptor for the T-cell receptor (TCR). Along with the TCR, the CD8 co-receptor plays a role in T cell signaling and aiding with cytotoxic T cell-antigen interactions...
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Granzyme B (redirect from Cytotoxic cell proteinase-1)
found in the granules of natural killer cells (NK cells) and cytotoxic T cells. It is secreted by these cells along with the pore forming protein perforin...
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Intravascular lymphomas (redirect from Angiotropic large cell lymphoma)
lymphoma (IVTL) in which the neoplastic cells are primarily, if not exclusively, a type of t-cell termed cytotoxic T-cells. Because of their similarities and...
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transformation of either one of two types of lymphocytes, NK cells or a T cell variant termed cytotoxic T cells, that are infected with the Epstein–Barr virus (EBV)...
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between the epithelial cells that line these organs' lumens. These IEL often exhibit natural killer and cytotoxic T-cell cell activation markers, contain...
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Cross-presentation (section Cross-presenting cells)
antigen-presenting cells (mostly dendritic cells) to take up, process and present extracellular antigens with MHC class I molecules to CD8 T cells (cytotoxic T cells)....
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Original antigenic sin (section In cytotoxic T cells)
immunological imprinting. A similar phenomenon has been described in cytotoxic T cells (CTL). It has been demonstrated that during a second infection by...
12 KB (1,251 words) - 00:30, 25 December 2023
The regulatory T cells (Tregs /ˈtiːrɛɡ/ or Treg cells), formerly known as suppressor T cells, are a subpopulation of T cells that modulate the immune...
79 KB (9,493 words) - 15:51, 21 June 2024
MHC class I attract T-lymphocytes called killer T-cells (also referred to as CD8-positive or cytotoxic T-cells) that destroy cells. Some new work has proposed...
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Antibody-dependent cellular cytotoxicity (ADCC), also referred to as antibody-dependent cell-mediated cytotoxicity, is a mechanism of cell-mediated immune defense...
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Immunotherapy (redirect from Regulatory T cell therapy)
such as lymphocytes, macrophages, dendritic cells, natural killer cells, and cytotoxic T lymphocytes work together to defend the body against cancer by targeting...
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II IFN is primarily secreted by CD4+ T helper 1 (Th1) cells, natural killer (NK) cells, and CD8+ cytotoxic T cells. The expression of type II IFN is upregulated...
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Lymphocyte (redirect from Lymphoid Cell)
cell (leukocyte) in the immune system of most vertebrates. Lymphocytes include T cells (for cell-mediated and cytotoxic adaptive immunity), B cells (for...
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Cytotoxic T-lymphocyte associated protein 4, (CTLA-4) also known as CD152 (cluster of differentiation 152), is a protein receptor that functions as an...
30 KB (3,464 words) - 22:51, 24 May 2024