membrane integrity and lyse. Cytotoxicity assays are widely used by the pharmaceutical industry to screen for cytotoxicity in compound libraries. Researchers...

Antibody-dependent cellular cytotoxicity (ADCC), also referred to as antibody-dependent cell-mediated cytotoxicity, is a mechanism of cell-mediated immune...

A cytotoxic T cell (also known as TC, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8+ T-cell or killer T cell) is a T lymphocyte (a...

Anti-reticular Cytotoxic Serum is made from the blood of a rabbit that has been injected with homogenized cadaver spleen and rib marrow. In small quantities...

cell-mediated cytotoxicity in normal human blood and the effect of the removal of various receptor-bearing cells on this cytotoxicity. Later that same...

Complement-dependent cytotoxicity (CDC) is an effector function of IgG and IgM antibodies. When they are bound to surface antigen on target cell (e.g....

Histotoxic hypoxia (also called histoxic hypoxia) is the inability of cells to take up or use oxygen from the bloodstream, despite physiologically normal...

regression of the primary tumor. Addressin Anergy Complete blood count Cytotoxicity Human leukocyte antigen Lymphocystivirus Lymphoproliferative disorders...

scientific discipline of toxicology, Cytotoxic T lymphocytes (CTLs) are generated by immune activation of cytotoxic T cells (Tc cells). They are generally...

radiation, surgery, and hyperthermia. Traditional chemotherapeutic agents are cytotoxic by means of interfering with cell division (mitosis) but cancer cells...

In excitotoxicity, nerve cells suffer damage or death when the levels of otherwise necessary and safe neurotransmitters such as glutamate become pathologically...

activation via the classical complement pathway Antibody-dependent cellular cytotoxicity or anti-receptor activity. The activation of the complement system results...

cyanide have been associated with cytotoxic edema and swelling of astrocytic cells. Hypoxia, anoxia can lead to cytotoxic edema through several mechanisms...

commonly found in the granules of natural killer cells (NK cells) and cytotoxic T cells. It is secreted by these cells along with the pore forming protein...

clearance through phagocytic destruction or antibody-dependent cellular cytotoxicity. Antibody-mediated opsonisation (marking) of pathogens depends on high...

Cytotoxic T-lymphocyte associated protein 4, (CTLA-4) also known as CD152 (cluster of differentiation 152), is a protein receptor that functions as an...

have moderate cytotoxicity again the KB and LoVo tumor cell lines, and this was attributed to cylindrocyclophane A. However, this cytotoxicity is not reserved...

Platinum-based antineoplastic drugs (informally called platins) are chemotherapeutic agents used to treat cancer. Their active moieties are coordination...

Tuftsin enhances the antigen-dependent cell-mediated immunity. Spleen cell cytotoxicity is augmented to a significant degree. The enhancement of antitumour immune...

rituximab mediates antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC). Rituximab has a general regulatory effect...

cytotoxicity against H460 cells. This sample did not show any more activity than the natural sample, implying that LcA only has moderate cytotoxicity...

cell-mediated immunity is the activation of phagocytes, antigen-specific cytotoxic T-lymphocytes, and the release of various cytokines in response to an...

study indicated that ECP caused cytotoxicity in HL-60 and HeLa cells via caspase-3 like activity. Accordingly, cytotoxic RNases play an important role in...

(or cancer cells) can present antigens originating inside the cell to cytotoxic T cells. In addition to the MHC family of proteins, antigen presentation...

receptor-independent cytotoxicity. In patients with severe COVID-19, CD16-positive T cells may lead to exacerbated cytotoxicity, promote microvascular...

fermentation. Neutral red can be used as a vital stain. The Neutral Red Cytotoxicity Assay was first developed by Ellen Borenfreund in 1984. In the Neutral...

enzymes and signaling pathways in the body, and may have dose-dependent cytotoxicity in living cells. Myristicin is listed in the Hazardous Substances Data...

The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF homology domain and forming trimers...

A-C exhibits cytotoxicity against human colon tumor cell line HCT-116 with IC50 value of 0.5 μg/mL. Aciculitin D exhibits cytotoxicity against human...

of determining neurotoxins when testing in-vitro, neurotoxicity and cytotoxicity may be difficult to distinguish as exposing neurons directly to compounds...