membrane integrity and lyse. Cytotoxicity assays are widely used by the pharmaceutical industry to screen for cytotoxicity in compound libraries. Researchers...

A cytotoxic T cell (also known as TC, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8+ T-cell or killer T cell) is a T lymphocyte (a...

Antibody-dependent cellular cytotoxicity (ADCC), also referred to as antibody-dependent cell-mediated cytotoxicity, is a mechanism of cell-mediated immune...

cell-mediated cytotoxicity in normal human blood and the effect of the removal of various receptor-bearing cells on this cytotoxicity. Later that same...

Anti-reticular Cytotoxic Serum is made from the blood of a rabbit that has been injected with homogenized cadaver spleen and rib marrow. In small quantities...

Complement-dependent cytotoxicity (CDC) is an effector function of IgG and IgM antibodies. When they are bound to surface antigen on target cell (e.g....

radiation, surgery, and hyperthermia. Traditional chemotherapeutic agents are cytotoxic by means of interfering with cell division (mitosis) but cancer cells...

regression of the primary tumor. Addressin Anergy Complete blood count Cytotoxicity Human leukocyte antigen Lymphocystivirus Lymphoproliferative disorders...

scientific discipline of toxicology, Cytotoxic T lymphocytes (CTLs) are generated by immune activation of cytotoxic T cells (Tc cells). They are generally...

Histotoxic hypoxia (also called histoxic hypoxia) is the inability of cells to take up or use oxygen from the bloodstream, despite physiologically normal...

cyanide have been associated with cytotoxic edema and swelling of astrocytic cells. Hypoxia, anoxia can lead to cytotoxic edema through several mechanisms...

activation via the classical complement pathway Antibody-dependent cellular cytotoxicity or anti-receptor activity. The activation of the complement system results...

clearance through phagocytic destruction or antibody-dependent cellular cytotoxicity. Antibody-mediated opsonisation (marking) of pathogens depends on high...

commonly found in the granules of natural killer cells (NK cells) and cytotoxic T cells. It is secreted by these cells along with the pore forming protein...

In excitotoxicity, nerve cells suffer damage or death when the levels of otherwise necessary and safe neurotransmitters such as glutamate become pathologically...

Tuftsin enhances the antigen-dependent cell-mediated immunity. Spleen cell cytotoxicity is augmented to a significant degree. The enhancement of antitumour immune...

oxidoreductases. Tetrazolium dye assays can also be used to measure cytotoxicity (loss of viable cells) or cytostatic activity (shift from proliferation...

study indicated that ECP caused cytotoxicity in HL-60 and HeLa cells via caspase-3 like activity. Accordingly, cytotoxic RNases play an important role in...

Cytotoxic T-lymphocyte associated protein 4, (CTLA-4) also known as CD152 (cluster of differentiation 152), is a protein receptor that functions as an...

for cell density determination via determination of cellular proteins (cytotoxicity assay). "Sulforhodamine B sodium salt (CAS 3520-42-1)". Santa Cruz Biotechnology...

rituximab mediates antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC). Rituximab has a general regulatory effect...

cell-mediated immunity is the activation of phagocytes, antigen-specific cytotoxic T-lymphocytes, and the release of various cytokines in response to an...

have moderate cytotoxicity again the KB and LoVo tumor cell lines, and this was attributed to cylindrocyclophane A. However, this cytotoxicity is not reserved...

1957, 13, 341–347. Masters R.W., Animal Cell Culture, Third Edition, Cytotoxicity and Viability Assays. Skehan P., Evaluation of Colorimetric Protein and...

The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF homology domain and forming trimers...

(or cancer cells) can present antigens originating inside the cell to cytotoxic T cells. In addition to the MHC family of proteins, antigen presentation...

fermentation. Neutral red can be used as a vital stain. The Neutral Red Cytotoxicity Assay was first developed by Ellen Borenfreund in 1984. In the Neutral...

of the time. This is more accurate than cytotoxigenic culture or cell cytotoxicity assay. Another benefit is that the result can be achieved within three...

of determining neurotoxins when testing in-vitro, neurotoxicity and cytotoxicity may be difficult to distinguish as exposing neurons directly to compounds...

(cytotoxic T cells). Cross-priming, the result of this process, describes the stimulation of naive cytotoxic CD8+ T cells into activated cytotoxic CD8+...