(cytosine-5)-methyltransferase 3-like is an enzyme that in humans is encoded by the DNMT3L gene. CpG methylation is an epigenetic modification that is important for...
11 KB (1,119 words) - 11:50, 28 March 2024
DNMT3L contains DNA methyltransferase motifs and is required for establishing maternal genomic imprints, despite being catalytically inactive. DNMT3L...
33 KB (3,598 words) - 17:16, 28 March 2024
(DNMTs). There are 5 DNMTs in humans: DNMT1, DNMT2, DNMT3A, DNMT3B, and DNMT3L, and in algae and fungi 3 more are present (DNMT4, DNMT5, and DNMT6). DNMT1...
23 KB (2,631 words) - 01:54, 18 December 2024
require a specific stimulation to acquire DNA methylation, via the cofactor 3 DNMT3L. Déborah Bourc'his runs a research team studying epigenetic decisions and...
5 KB (466 words) - 19:03, 29 December 2024
homolog A DNAJC28: encoding protein DnaJ homolog subfamily C member 28 DNMT3L: encoding protein DNA (cytosine-5)-methyltransferase 3-like DOP1B: encoding...
33 KB (3,074 words) - 21:55, 28 December 2024
major protein domains: the Pro-Trp-Trp-Pro (PWWP) domain, the ATRX-DNMT3-DNMT3L (ADD) domain and the catalytic methyltransferase domain. The structures...
34 KB (3,924 words) - 10:55, 28 March 2024
HGNC:2976 P26358 4446 DNMT3A HGNC:2978 Q9Y6K1 4447 DNMT3B HGNC:2979 Q9UBC3 4448 DNMT3L HGNC:2980 Q9UJW3 4449 DNPEP HGNC:2981 Q9ULA0 4450 DNPH1 HGNC:21218 O43598...
277 KB (17 words) - 18:34, 6 October 2024
early in development. DNMT3L is a protein that is homologous to the other DNMT3s but has no catalytic activity. Instead, DNMT3L assists the de novo methyltransferases...
116 KB (13,344 words) - 21:21, 25 December 2024
2005.11.007. PMID 16337666. Hata K, Okano M, Lei H, Li E (April 2002). "Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish...
69 KB (8,308 words) - 22:01, 1 December 2024
PMID 11932749. S2CID 4397868. Hata K, Okano M, Lei H, Li E (April 2002). "Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish...
12 KB (1,443 words) - 11:50, 28 March 2024
CBFA2T3, CDC20, CDH1, CHD3, CHD4, COUP-TFII, CTBP1, DDX17, DDX5, DNMT3A, DNMT3L, Death-associated protein 6, EED, EVI1, EZH2, FKBP3, GATA1, HMG20B, HSPA4...
50 KB (5,476 words) - 01:27, 4 January 2024
Tempst, Paul; Lin, Shau-Ping; Allis, C. David; Cheng, Xiaodong (2007). "DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA"...
11 KB (1,039 words) - 03:45, 4 February 2024
2016). "Global hypermethylation in fetal cortex of Down syndrome due to DNMT3L overexpression". Hum. Mol. Genet. 25 (9): 1714–27. doi:10.1093/hmg/ddw043...
4 KB (511 words) - 00:41, 30 November 2023