Dopamine receptor D3 (redirect from DRD3)
Dopamine receptor D3 is a protein that in humans is encoded by the DRD3 gene. This gene encodes the D3 subtype of the dopamine receptor. The D3 subtype...
28 KB (3,179 words) - 05:11, 26 September 2024
Yes No Yes Altered striatal dopamine signaling ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD2 ↑DRD2 Altered striatal opioid signaling No change...
26 KB (3,135 words) - 00:26, 2 October 2024
containing mainly D1-type (i.e., DRD1 and DRD5) or D2-type (i.e., DRD2, DRD3, and DRD4) dopamine receptors. A subpopulation of MSNs contain both D1-type...
80 KB (9,795 words) - 16:39, 15 April 2024
Yes No Yes Altered striatal dopamine signaling ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD2 ↑DRD2 Altered striatal opioid signaling No change...
156 KB (15,356 words) - 13:43, 3 October 2024
Decrease intracellular levels of cAMP by inhibiting adenylate cyclase. D3 DRD3 D4 DRD4 TAAR TAAR1 TAAR1 Gs-coupled. Gq-coupled. Increase intracellular levels...
139 KB (14,249 words) - 04:40, 28 September 2024
Yes No Yes Altered striatal dopamine signaling ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD2 ↑DRD2 Altered striatal opioid signaling No change...
223 KB (25,730 words) - 09:21, 7 October 2024
Yes No Yes Altered striatal dopamine signaling ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD2 ↑DRD2 Altered striatal opioid signaling No change...
57 KB (21,441 words) - 18:33, 3 October 2024
Yes No Yes Altered striatal dopamine signaling ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD2 ↑DRD2 Altered striatal opioid signaling No change...
273 KB (26,900 words) - 06:46, 25 September 2024
Yes No Yes Altered striatal dopamine signaling ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD2 ↑DRD2 Altered striatal opioid signaling No change...
94 KB (9,655 words) - 03:24, 11 August 2024
dyskinesia in chronic schizophrenia: Additive contribution of 5-HT2C ser and DRD3 gly alleles to susceptibility". Psychopharmacology. 152 (4): 408–413. doi:10...
37 KB (3,897 words) - 03:19, 26 September 2024
Yes No Yes Altered striatal dopamine signaling ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD2 ↑DRD2 Altered striatal opioid signaling No change...
58 KB (20,574 words) - 07:42, 1 October 2024
has been shown to form heterodimers in vitro (and possibly in vivo) with DRD3, DRD5, and 5-HT2A. Prolactin modulator D2sh–TAAR1 is a presynaptic heterodimer...
35 KB (3,960 words) - 05:11, 26 September 2024
RD6 DRD6 DRD6 DRD6 9 RD5 DRD5 DRD5 DRD5 10 RD4 DRD4 DRD4 DRD4 11 RD3 DRD3 DRD3 DRD3 12 RD2 DRD2 DRD2 DRD2 13 RD1 DRD1 DRD1 DRD1 14 RD0 DRD0 DRD0 DRD0 Data...
11 KB (703 words) - 02:00, 20 January 2024
synthetic partial agonist. D3 is encoded by the Dopamine receptor D3 gene (DRD3). Maximum expression of dopamine D3 receptors is noted in the islands of...
50 KB (5,330 words) - 03:50, 17 June 2024
Markett, Sebastian; Melchers, Martin; Reuter, Martin (March 2015). "The DRD3 Ser9Gly polymorphism, Machiavellianism, and its link to schizotypal personality"...
152 KB (17,996 words) - 14:43, 3 October 2024
Yes No Yes Altered striatal dopamine signaling ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD2 ↑DRD2 Altered striatal opioid signaling No change...
65 KB (7,751 words) - 06:03, 2 October 2024
HGNC:27446 Q494R4 4533 DRD1 HGNC:3020 P21728 4534 DRD2 HGNC:3023 P14416 4535 DRD3 HGNC:3024 P35462 4536 DRD4 HGNC:3025 P21917 4537 DRD5 HGNC:3026 P21918 4538...
277 KB (17 words) - 18:34, 6 October 2024
Yes No Yes Altered striatal dopamine signaling ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD2 ↑DRD2 Altered striatal opioid signaling No change...
57 KB (7,191 words) - 06:17, 25 July 2024
Yes No Yes Altered striatal dopamine signaling ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD2 ↑DRD2 Altered striatal opioid signaling No change...
32 KB (3,976 words) - 13:09, 18 January 2024
Dopamine receptor InterPro: IPR000929 D1 (DRD1, DADR) D2 (DRD2, D2DR) D3 (DRD3, D3DR) D4 (DRD4, D4DR) D5 (DRD5, DBDR) Trace amine receptor InterPro: IPR009132...
25 KB (2,172 words) - 01:01, 29 November 2023
pore Nuclear membrane Plasma membrane Cav1.2 NMDAR AMPAR DRD1 DRD5 DRD2 DRD3 DRD4 Gs Gi/o AC cAMP cAMP PKA CaM CaMKII DARPP-32 PP1 PP2B CREB ΔFosB JunD...
26 KB (3,991 words) - 05:29, 10 July 2024
to block cue-induced reinstatement of nicotine-seeking, indicating that DRD3 selective antagonism may be an effective approach to prevent relapse for...
7 KB (608 words) - 20:06, 23 September 2024
pore Nuclear membrane Plasma membrane Cav1.2 NMDAR AMPAR DRD1 DRD5 DRD2 DRD3 DRD4 Gs Gi/o AC cAMP cAMP PKA CaM CaMKII DARPP-32 PP1 PP2B CREB ΔFosB JunD...
63 KB (8,159 words) - 01:16, 5 June 2024
DRD3 Identifiers Aliases DRD3, D3DR, ETM1, FET1, dopamine receptor D3 External IDs OMIM: 126451; MGI: 94925; HomoloGene: 623; GeneCards: DRD3; OMA:DRD3...
639 bytes (90 words) - 01:02, 7 November 2021
oliveria, Carlos, Pato (2004)"Family association study between DRD2 and DRD3 gene polymorphisms and schizophrenia in a portuguese population". Psychiatry...
4 KB (663 words) - 04:55, 29 December 2023
S2CID 34029937. de Krom M, Staal WG, Ophoff RA, et al. (2009). "A common variant in DRD3 receptor is associated with autism spectrum disorder". Biol. Psychiatry....
8 KB (1,029 words) - 03:37, 29 November 2023
PMID 18600204. de Krom M, Staal WG, Ophoff RA, et al. (2009). "A common variant in DRD3 receptor is associated with autism spectrum disorder". Biol. Psychiatry....
7 KB (976 words) - 21:06, 27 November 2023
Curran S, van Engeland H, van Ree JM (April 2009). "A common variant in DRD3 receptor is associated with autism spectrum disorder". Biological Psychiatry...
4 KB (509 words) - 02:53, 28 November 2023
PMID 14559917. de Krom M, Staal WG, Ophoff RA, et al. (2009). "A common variant in DRD3 receptor is associated with autism spectrum disorder". Biol. Psychiatry....
16 KB (1,935 words) - 21:41, 9 March 2024