Dihydrofolic acid (conjugate base dihydrofolate) (DHF) is a folic acid (vitamin B9) derivative which is converted to tetrahydrofolic acid by dihydrofolate...
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Tetrahydrofolic acid (THFA), or tetrahydrofolate, is a folic acid derivative. Tetrahydrofolic acid is produced from dihydrofolic acid by dihydrofolate...
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and inhibit conversion of PABA and dihydropteroate diphosphate to dihydrofolic acid, or dihydrofolate. Inhibiting the production of dihydrofolate intermediate...
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dihydrofolate reductase and inhibits the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF). THF is an essential precursor in the thymidine...
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Dihydrofolate reductase, or DHFR, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as an electron donor, which can be converted...
40 KB (4,585 words) - 06:01, 23 September 2024
diaminopyrimidines such as trimethoprim, inhibits the reduction of dihydrofolic acid to tetrahydrofolic acid by bacterial cells. Hofacre CL, Fricke JA, Inglis T (2013)...
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of dihydrofolic acid in many microorganisms. The enzyme dihydropteroate synthetase converts pteridine and 4-aminobenzoic acid to dihydrofolic acid in...
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synthesis of dihydrofolic acid, via competition with para-aminobenzoate for the active site of dihydropteroate synthase, thereby inhibiting nucleic acid synthesis...
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Dihydropteroate (redirect from Dihydropteroic acid)
tract, Shigella, Salmonella, and Pneumocystis jivoreci infections. Dihydrofolic acid GHS: GESTIS 492946 Hevener, Kirk E; Yun, Mi-Kyung; Qi, Jianjun; Kerr...
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dihydropterin-CH2OH-diphosphate) is a pteridine; a precursor to dihydrofolic acid. Derrick, J. P (2008). The structure and mechanism of 6-hydroxymethyl-7...
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10-Methylenetetrahydrofolic acid and dCMP, whereas its two products are dihydrofolic acid and deoxy-5-methylcytidylic acid. This enzyme belongs to the...
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structural analogs of p-aminobenzoic acid (PABA) and compete with PABA to block its conversion to dihydrofolic acid. Sulfonamides act on the schizont stages...
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refer to: Acute decompensated heart failure Diastolic heart failure Dihydrofolic acid Dengue hemorrhagic fever Danish Handball Federation (Danish: Dansk...
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synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. It is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA)....
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reductase, the enzyme responsible for the reduction of dihydrofolic acid to tetrahydrofolic acid, but rather to defective folate metabolism. In addition...
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antagonism with para-aminobenzoic acid, inhibiting the dihydropteroate synthetase enzyme crucial for dihydrofolic acid synthesis. This inhibition disrupts...
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Biosynthesis of Folic Acid. III. Enzymatic Formation of Dihydrofolic Acid from Dihydropteroic Acid and of Tetrahydropteroylpolyglutamic Acid Compounds from Tetrahydrofolic...
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J.; Freeman, M.; Huennekens, F. M. (February 1958). "Inhibition of dihydrofolic reductase by aminopterin and amethopterin". Proceedings of the Society...
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2-aminopyrimidin-4(3H)-ones bearing 1,2,3-benzotriazinyl groups as potential dihydrofolic reductase inhibitors". Journal of the Chemical Society, Perkin Transactions...
3 KB (243 words) - 13:34, 8 January 2024