• Thumbnail for Dihydrofolic acid
    Dihydrofolic acid (conjugate base dihydrofolate) (DHF) is a folic acid (vitamin B9) derivative which is converted to tetrahydrofolic acid by dihydrofolate...
    3 KB (165 words) - 15:31, 5 June 2022
  • Thumbnail for Tetrahydrofolic acid
    Tetrahydrofolic acid (THFA), or tetrahydrofolate, is a folic acid derivative. Tetrahydrofolic acid is produced from dihydrofolic acid by dihydrofolate...
    7 KB (447 words) - 23:07, 4 November 2023
  • Thumbnail for Sulfamethoxazole
    and inhibit conversion of PABA and dihydropteroate diphosphate to dihydrofolic acid, or dihydrofolate. Inhibiting the production of dihydrofolate intermediate...
    12 KB (982 words) - 15:35, 8 October 2024
  • Thumbnail for Trimethoprim
    dihydrofolate reductase and inhibits the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF). THF is an essential precursor in the thymidine...
    18 KB (1,411 words) - 21:40, 19 October 2024
  • Thumbnail for Dihydrofolate reductase
    Dihydrofolate reductase, or DHFR, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as an electron donor, which can be converted...
    40 KB (4,585 words) - 06:01, 23 September 2024
  • Thumbnail for Ormetoprim
    diaminopyrimidines such as trimethoprim, inhibits the reduction of dihydrofolic acid to tetrahydrofolic acid by bacterial cells. Hofacre CL, Fricke JA, Inglis T (2013)...
    4 KB (125 words) - 04:57, 30 June 2024
  • Thumbnail for Pterin
    of dihydrofolic acid in many microorganisms. The enzyme dihydropteroate synthetase converts pteridine and 4-aminobenzoic acid to dihydrofolic acid in...
    12 KB (1,076 words) - 16:10, 23 September 2024
  • Thumbnail for Dapsone
    synthesis of dihydrofolic acid, via competition with para-aminobenzoate for the active site of dihydropteroate synthase, thereby inhibiting nucleic acid synthesis...
    37 KB (3,765 words) - 05:54, 2 November 2024
  • Thumbnail for Dihydropteroate
    tract, Shigella, Salmonella, and Pneumocystis jivoreci infections. Dihydrofolic acid GHS: GESTIS 492946 Hevener, Kirk E; Yun, Mi-Kyung; Qi, Jianjun; Kerr...
    4 KB (133 words) - 12:35, 3 March 2024
  • Thumbnail for 2-Amino-4-hydroxy-6-pyrophosphoryl-methylpteridine
    dihydropterin-CH2OH-diphosphate) is a pteridine; a precursor to dihydrofolic acid. Derrick, J. P (2008). The structure and mechanism of 6-hydroxymethyl-7...
    2 KB (60 words) - 18:17, 18 August 2022
  • 10-Methylenetetrahydrofolic acid and dCMP, whereas its two products are dihydrofolic acid and deoxy-5-methylcytidylic acid. This enzyme belongs to the...
    2 KB (128 words) - 13:47, 26 August 2023
  • structural analogs of p-aminobenzoic acid (PABA) and compete with PABA to block its conversion to dihydrofolic acid. Sulfonamides act on the schizont stages...
    64 KB (7,340 words) - 21:00, 20 October 2024
  • refer to: Acute decompensated heart failure Diastolic heart failure Dihydrofolic acid Dengue hemorrhagic fever Danish Handball Federation (Danish: Dansk...
    407 bytes (73 words) - 07:05, 23 October 2024
  • Thumbnail for Sulfacetamide
    synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. It is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA)....
    19 KB (1,841 words) - 15:32, 8 October 2024
  • Thumbnail for Primidone
    reductase, the enzyme responsible for the reduction of dihydrofolic acid to tetrahydrofolic acid, but rather to defective folate metabolism. In addition...
    90 KB (6,948 words) - 11:26, 5 August 2024
  • Thumbnail for Phthalylsulfathiazole
    antagonism with para-aminobenzoic acid, inhibiting the dihydropteroate synthetase enzyme crucial for dihydrofolic acid synthesis. This inhibition disrupts...
    7 KB (478 words) - 05:52, 2 November 2024
  • Thumbnail for Dihydrofolate synthase
    Biosynthesis of Folic Acid. III. Enzymatic Formation of Dihydrofolic Acid from Dihydropteroic Acid and of Tetrahydropteroylpolyglutamic Acid Compounds from Tetrahydrofolic...
    4 KB (393 words) - 15:16, 22 September 2024
  • Thumbnail for Mary Jane Osborn
    J.; Freeman, M.; Huennekens, F. M. (February 1958). "Inhibition of dihydrofolic reductase by aminopterin and amethopterin". Proceedings of the Society...
    12 KB (1,025 words) - 20:21, 11 September 2024
  • Thumbnail for Bropirimine
    2-aminopyrimidin-4(3H)-ones bearing 1,2,3-benzotriazinyl groups as potential dihydrofolic reductase inhibitors". Journal of the Chemical Society, Perkin Transactions...
    3 KB (243 words) - 13:34, 8 January 2024