growth response protein 2 is a protein that in humans is encoded by the EGR2 gene. EGR2 (also termed Krox20) is a transcription regulatory factor, containing...
18 KB (2,066 words) - 06:31, 30 January 2023
continuative study discovered that the Ewing sarcoma susceptibility gene EGR2, which is located within the chromosome 10 susceptibility locus, is regulated...
41 KB (4,430 words) - 13:45, 10 May 2024
Specifically, it has been associated with mutations in MPZ, PMP22, PRX, and EGR2 genes. The disorder is inherited in an autosomal dominant or autosomal recessive...
8 KB (657 words) - 12:53, 21 August 2024
ENSG00000120738 C2H2 ZF Known motif – High-throughput in vitro [185] MCGCCCMCGCA EGR2 ENSG00000122877 C2H2 ZF Known motif – High-throughput in vitro [186] MCGCCCACGCD...
374 KB (81 words) - 02:10, 23 September 2023
microsatellite which binds a transcription factor, which in turn activates the EGR2 gene which drives the cancer. In addition, other GGAA microsatellites may...
67 KB (7,394 words) - 16:46, 2 September 2024
zinc finger transcription factors. Members of the family include: EGR1, EGR2, EGR3 and EGR4 Gómez-Martín D, Díaz-Zamudio M, Galindo-Campos M, Alcocer-Varela...
908 bytes (86 words) - 17:50, 7 April 2022
pathways and dysfunction of transcriptional factors like KNOX20, SOX10 and EGR2. PMP22 has been found to interact with several different factors, some of...
12 KB (1,472 words) - 20:31, 4 August 2024
J (May 2007). "Neuropathy-Associated Egr2 Mutants Disrupt Cooperative Activation of Myelin Protein Zero by Egr2 and Sox10". Mol. Cell. Biol. 27 (9): 3521–29...
16 KB (1,872 words) - 22:20, 4 February 2024
Endogenous Bornavirus-like nucleoprotein 1 ECD: ecdysoneless cell cycle regulator EGR2: early growth response 2 (Krox-20 homolog, Drosophila) EIF5AP1: eukaryotic...
28 KB (1,967 words) - 02:02, 11 April 2024
HGNC:14660 Q96KS0 4778 EGLN3 HGNC:14661 Q9H6Z9 4779 EGR1 HGNC:3238 P18146 4780 EGR2 HGNC:3239 P11161 4781 EGR3 HGNC:3240 Q06889 4782 EGR4 HGNC:3241 Q05215 4783...
277 KB (17 words) - 18:34, 6 October 2024
infancy. Average NCV: 26–42 m/s. Symptoms are identical to CMT1A. CMT1D 607678 EGR2 10q21.3 Autosomal dominant Average NCV: 15–20 m/s CMT1E 118300 PMP22 17p11...
14 KB (276 words) - 01:02, 3 March 2024
potential molecular convergence involves the early growth response gene-2 (EGR2). EGR2 is the only gene in the EGR family that is restricted to the central...
52 KB (6,263 words) - 12:20, 11 October 2024
highly expressed throughout organoid development. However, hindbrain markers EGR2 and ISL1 show early presence but a decrease in the later stages. This imbalance...
52 KB (6,277 words) - 00:19, 10 November 2024
Unoki M, Nakamura Y (Aug 2001). "Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway". Oncogene. 20 (33): 4457–65...
21 KB (2,677 words) - 04:06, 9 June 2024
the mammalian growth regulated early growth response protein 1 (EGR1) and (EGR2) proteins. Mutations of Wilms' tumor suppressor gene1 (WT1) are associated...
27 KB (3,085 words) - 19:38, 2 October 2024
Unoki M, Nakamura Y (Aug 2001). "Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway". Oncogene. 20 (33): 4457–65...
4 KB (452 words) - 20:43, 18 October 2022
various stimuli. Also was shown its role in T-cell clonal anergy downstream of Egr2, where NDRG1 is upregulated in the absence of costimulation to inhibit subsequent...
18 KB (2,179 words) - 12:59, 23 December 2023
Venken K, Di Maria E, Bellone E, et al. (2003). "Search for mutations in the EGR2 corepressor proteins, NAB1 and NAB2, in human peripheral neuropathies". Neurogenetics...
7 KB (850 words) - 18:48, 13 August 2023
co-complex interactions. NDUFS2 appears to interact with NDUFS3, MKLN1, EGR2, HMOX2, CENPU, and TNFRSF14. Biology portal NDUFS1 GRCh38: Ensembl release...
15 KB (1,807 words) - 06:18, 11 November 2024
Gilardi-Hebenstreit P, Rossert J, Ruggiero F, Duprez D (February 2011). "EGR1 and EGR2 involvement in vertebrate tendon differentiation". The Journal of Biological...
27 KB (3,311 words) - 22:03, 8 July 2024
disease type 1C; 601098; LITAF Charcot–Marie–Tooth disease type 1D; 607678; EGR2 Charcot–Marie–Tooth disease type 1E; 118300; PMP22 Charcot–Marie–Tooth disease...
234 KB (18,877 words) - 06:16, 6 November 2024
Venken K, Di Maria E, Bellone E, et al. (2003). "Search for mutations in the EGR2 corepressor proteins, NAB1 and NAB2, in human peripheral neuropathies". Neurogenetics...
5 KB (573 words) - 21:42, 27 March 2024
factor PU.1 8 V$ZKSCAN3.01 Zinc finger with KRAB and SCAN domains 3 9 V$EGR2.03 Early growth response 2 10 V$ZNF300.01 KRAB-containing zinc finger protein...
14 KB (952 words) - 21:54, 30 April 2024