• enzymology, an elongation factor 2 kinase (EC 2.7.11.20) is an enzyme that catalyzes the chemical reaction: ATP + [elongation factor 2] ⇌ {\displaystyle...
    7 KB (893 words) - 13:57, 26 August 2023
  • Thumbnail for EEF2
    EEF2 (redirect from Elongation factor 2)
    Eukaryotic elongation factor 2 is a protein that in humans is encoded by the EEF2 gene. It is the archaeal and eukaryotic counterpart of bacterial EF-G...
    9 KB (1,045 words) - 02:36, 17 April 2022
  • Thumbnail for EEF2K
    Eukaryotic elongation factor-2 kinase (eEF-2 kinase or eEF-2K), also known as calmodulin-dependent protein kinase III (CAMKIII) and calcium/calmodulin-dependent...
    13 KB (1,651 words) - 02:49, 22 August 2023
  • Thumbnail for Protein kinase, AMP-activated, alpha 1
    KS, et al. (2001). "Phosphorylation of elongation factor-2 kinase on serine 499 by cAMP-dependent protein kinase induces Ca2+/calmodulin-independent activity"...
    10 KB (1,255 words) - 06:02, 24 June 2024
  • Thumbnail for Protein kinase A
    levels of cyclic AMP (cAMP). PKA is also known as cAMP-dependent protein kinase (EC 2.7.11.11). PKA has several functions in the cell, including regulation...
    27 KB (2,665 words) - 17:03, 6 April 2024
  • Thumbnail for Cyclin-dependent kinase 2
    Cyclin-dependent kinase 2, also known as cell division protein kinase 2, or Cdk2, is an enzyme that in humans is encoded by the CDK2 gene. The protein...
    35 KB (4,314 words) - 00:26, 6 July 2024
  • Thumbnail for AMP-activated protein kinase
    5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular...
    65 KB (7,147 words) - 05:41, 24 June 2024
  • lymphocytes. The IκB kinase enzyme complex is part of the upstream NF-κB signal transduction cascade. The IκBα (inhibitor of nuclear factor kappa B) protein...
    14 KB (1,447 words) - 09:31, 22 December 2023
  • transduction MAP kinase MAP kinase kinase kinase MAP kinase kinase kinase kinase Dérijard B, et al. (1995). "Independent human MAP-kinase signal transduction...
    3 KB (296 words) - 17:06, 14 September 2023
  • A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses...
    46 KB (5,492 words) - 03:05, 21 June 2024
  • Thumbnail for Cyclin-dependent kinase 9
    cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed...
    12 KB (1,460 words) - 23:03, 27 March 2024
  • Thumbnail for Serine/threonine-specific protein kinase
    A serine/threonine protein kinase (EC 2.7.11.-) is a kinase enzyme, in particular a protein kinase, that phosphorylates the OH group of the amino-acid...
    14 KB (1,210 words) - 13:35, 14 June 2024
  • Thumbnail for Myosin light-chain kinase
    Myosin light-chain kinase also known as MYLK or MLCK is a serine/threonine-specific protein kinase that phosphorylates a specific myosin light chain,...
    16 KB (1,731 words) - 22:49, 9 January 2024
  • Thumbnail for C-Jun N-terminal kinases
    c-Jun N-terminal kinases (JNKs), were originally identified as kinases that bind and phosphorylate c-Jun on Ser-63 and Ser-73 within its transcriptional...
    14 KB (1,626 words) - 20:50, 30 May 2024
  • Thumbnail for Alexey G. Ryazanov
    protein kinases — alpha-kinases. One of the alpha-kinases, elongation factor-2 kinase (eEF2 kinase), can regulate the global protein synthesis rate and...
    7 KB (673 words) - 22:55, 22 February 2024
  • Thumbnail for Cyclin-dependent kinase
    Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases involved in the regulation of the cell cycle and its progression...
    35 KB (3,829 words) - 14:24, 17 June 2024
  • Thumbnail for Ribosomal s6 kinase
    phosphatase 1; glycogen synthase kinase 3 (GSK3); L1 CAM, a neural cell adhesion molecule; Son of Sevenless, the Ras exchange factor; and Myt1, an inhibitor of...
    5 KB (510 words) - 17:10, 16 September 2021
  • serine/threonine-specific protein kinases. Activated CAMK is involved in the phosphorylation of transcription factors and therefore, in the regulation...
    8 KB (886 words) - 12:46, 31 January 2024
  • Thumbnail for MTOR
    functions as a tyrosine protein kinase that promotes the activation of insulin receptors and insulin-like growth factor 1 receptors. mTORC2 has also been...
    119 KB (12,654 words) - 00:05, 31 July 2024
  • Mitogen-activated protein kinase kinase kinase kinase (MAP4K) is a family of proteins involved in cellular signal transduction. MAP4K1 (aka HPK1) MAP4K2...
    880 bytes (84 words) - 18:46, 3 April 2021
  • In cell biology, Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling...
    27 KB (2,716 words) - 18:23, 1 August 2024
  • Thumbnail for Protein kinase B
    Protein kinase B (PKB), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple...
    35 KB (3,831 words) - 00:20, 19 July 2024
  • Thumbnail for Rho-associated protein kinase
    proteins: Adducin, EF-1&alpha (elongation factor, translation co-factor), MARCKS (myristylated alanine-rich C kinase substrate), Caponin (unknown function)...
    19 KB (2,170 words) - 06:41, 27 May 2024
  • Thumbnail for Cyclin-dependent kinase 7
    MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription...
    20 KB (2,347 words) - 23:01, 27 March 2024
  • Thumbnail for P70-S6 Kinase 1
    Ribosomal protein S6 kinase beta-1 (S6K1), also known as p70S6 kinase (p70S6K, p70-S6K), is an enzyme (specifically, a protein kinase) that in humans is...
    17 KB (2,127 words) - 02:01, 8 April 2024
  • Casein kinase 2 (EC 2.7.11.1)(CK2/CSNK2) is a serine/threonine-selective protein kinase that has been implicated in cell cycle control, DNA repair, regulation...
    11 KB (1,130 words) - 09:40, 22 April 2023
  • Thumbnail for Cyclin-dependent kinase 4
    Cyclin-dependent kinase 4 also known as cell division protein kinase 4 is an enzyme that in humans is encoded by the CDK4 gene. CDK4 is a member of the...
    21 KB (2,372 words) - 12:19, 28 July 2024
  • Thumbnail for Pyruvate dehydrogenase kinase
    Pyruvate dehydrogenase kinase (also pyruvate dehydrogenase complex kinase, PDC kinase, or PDK; EC 2.7.11.2) is a kinase enzyme which acts to inactivate...
    14 KB (1,711 words) - 16:27, 25 October 2023
  • Thumbnail for RAF kinase
    RAF kinases are a family of three serine/threonine-specific protein kinases that are related to retroviral oncogenes. The mouse sarcoma virus 3611 contains...
    5 KB (556 words) - 08:06, 3 June 2024
  • been shown to phosphorylate and activate MAPKAP kinase 2 and to phosphorylate the transcription factors ATF2, Mac, MEF2, and p53. p38 also has been shown...
    14 KB (1,385 words) - 10:32, 28 April 2024