Exonucleases are enzymes that work by cleaving nucleotides one at a time from the end (exo) of a polynucleotide chain. A hydrolyzing reaction that breaks...

3'–5' exonuclease domain responsible for proofreading has been dramatically changed and is not functional. It has a functional 5'-3' exonuclease domain...

Exonuclease I may refer to one of two enzymes: Phosphodiesterase I Exodeoxyribonuclease I This disambiguation page lists articles associated with the...

Spleen exonuclease (EC 3.1.16.1, 3'-exonuclease, spleen phosphodiesterase, 3'-nucleotide phosphodiesterase, phosphodiesterase II) is an enzyme. This enzyme...

Venom exonuclease (EC 3.1.15.1, venom phosphodiesterase) is an enzyme. This enzyme catalyses the following chemical reaction Exonucleolytic cleavage in...

recognized, DNA polymerase moves backwards by one base pair of DNA. The 3'–5' exonuclease activity of the enzyme allows the incorrect base pair to be excised (this...

Exonuclease 1 is an enzyme that in humans is encoded by the EXO1 gene. This gene encodes a protein with 5' to 3' exonuclease activity as well as RNase...

lambda exonuclease, phage lambda-induced exonuclease, Escherichia coli exonuclease IV, E. coli exonuclease IV, exodeoxyribonuclease IV, exonuclease IV) is...

Escherichia coli exonuclease VII, E. coli exonuclease VII, endodeoxyribonuclease VII, exodeoxyribonuclease VII) is a bacterial exonuclease enzyme. It is...

Exonuclease III (ExoIII) is an enzyme that belongs to the exonuclease family. ExoIII catalyzes the stepwise removal of mononucleotides from 3´-hydroxyl...

Exodeoxyribonuclease V (EC 3.1.11.5, RecBCD, Exonuclease V, Escherichia coli exonuclease V, E. coli exonuclease V, gene recBC endoenzyme, RecBC deoxyribonuclease...

Exonuclease 5 is a protein that in humans is encoded by the EXO5 gene. The protein encoded by this gene is a single-stranded DNA (ssDNA)-specific exonuclease...

a template strand A 3'→5' (reverse) exonuclease activity that mediates proofreading A 5'→3' (forward) exonuclease activity mediating nick translation...

Exodeoxyribonuclease III (EC 3.1.11.2, Escherichia coli exonuclease III, E. coli exonuclease III, endoribonuclease III) is an enzyme that catalyses the...

Ribonuclease T (RNase T, exonuclease T, exo T) is a ribonuclease enzyme involved in the maturation of transfer RNA and ribosomal RNA in bacteria, as well...

activity and the 3’ → 5’ exonuclease activity for removal of precoding nucleotides and proofreading, but loses its 5' → 3' exonuclease activity. The other...

only at very specific nucleotide sequences. Endonucleases differ from exonucleases, which cleave the ends of recognition sequences instead of the middle...

all have a 5'→3' polymerase activity, and either a 5'→3' or a 3'→5' exonuclease activity. DNA polymerases are roughly shaped like a hand with a thumb...

components. The three required enzyme activities are: exonuclease, DNA polymerase, and DNA ligase. The exonuclease chews back DNA from the 5' end, thus not inhibiting...

Exodeoxyribonuclease I (EC 3.1.11.1, Escherichia coli exonuclease I, E. coli exonuclease I, exonuclease I) is an enzyme that catalyses the following chemical...

family. It is the only RecQ Helicase that contains 3' to 5' exonuclease activity. These exonuclease activities include degradation of recessed 3' ends and...

prime repair exonuclease 1 is an enzyme that in humans is encoded by the TREX1 gene. This gene encodes the major 3'->5' DNA exonuclease in human cells...

degradation by the exonuclease, a 5' cap is added to the strand. This is a modified guanine added to the front of mRNA, which prevents the exonuclease from binding...

degraded. However, it is difficult to degrade C↓pC, C↓pG site. Mung bean exonuclease is a nuclease derived from mung beans that removes nucleotides in a step-wise...

Nucleases that hydrolyse nucleotides from the ends of DNA strands are called exonucleases, while endonucleases cut within strands. The most frequently used nucleases...

research applications. The TaqMan probe principle relies on the 5´–3´ exonuclease activity of Taq polymerase to cleave a dual-labeled probe during hybridization...

polymerase possesses a 3’-5’ single and double stranded DNA exonuclease activity. This exonuclease activity is activated when a newly synthesized base does...

multiple enzymatic activities as both a poly(A) 3′-5′ exonuclease and a ubiquitin ligase. The exonuclease activity of CCR4-Not shortens the poly(A) tail found...

possesses 3' to 5' exonuclease proofreading activity, meaning that as the DNA is assembled from the 5' end to 3' end, the exonuclease activity immediately...

strand to be excised as it goes. An exonuclease trails the complex and digests the ss-DNA tail. The exonuclease recruited is dependent on which side...