An exoribonuclease is an exonuclease ribonuclease, which are enzymes that degrade RNA by removing terminal nucleotides from either the 5' end or the 3'...

components. Ribonucleases can be divided into endoribonucleases and exoribonucleases, and comprise several sub-classes within the EC 2.7 (for the phosphorolytic...

Exoribonuclease H (EC 3.1.13.2) is an enzyme. This enzyme catalyses the following chemical reaction 3'-end directed exonucleolytic cleavage of viral RNA-DNA...

5′-3′ exoribonuclease 1 (Xrn1) is a protein that in humans is encoded by the XRN1 gene. Xrn1 hydrolyses RNA in the 5′ to 3′ direction. This gene encodes...

Exoribonuclease II (EC 3.1.13.1, ribonuclease II, ribonuclease Q, BN ribonuclease, Escherichia coli exo-RNase II, RNase II, exoribonuclease (misleading)...

5'-3' Exoribonuclease 2 (XRN2) also known as Dhm1-like protein is an exoribonuclease enzyme that in humans is encoded by the XRN2 gene. The human gene...

coronavirus genome is a non-structural protein, nsp14, that is a 3’-to-5’ exoribonuclease (ExoN). This protein resides in the protein complex nsp10-nsp14 that...

multi-protein exosome complex, which consists largely of 3′ to 5′ exoribonucleases. RNA polymerase II is known to be in effect during transcriptional...

The protein nsp14 is a 3'-5' exoribonuclease which provides extra fidelity to the replication process. The exoribonuclease provides a proofreading function...

as RNA-dependent RNA polymerase (nsp12), RNA helicase (nsp13), and exoribonuclease (nsp14). A number of the nonstructural proteins coalesce to form a...

likely possess replication proofreading mechanisms in the form of an exoribonuclease within nonstructural protein nsp14. Positive-strand RNA viruses have...

Nucleotidyltransferases (EC 2.7.7) Enzymes that have phosphorolytic 3' to 5' exoribonuclease activity (break phosphodiester bond) RNase PH Polynucleotide Phosphorylase...

RNase R, or Ribonuclease R, is a 3'-->5' exoribonuclease, which belongs to the RNase II superfamily, a group of enzymes that hydrolyze RNA in the 3' -...

mature miRNAs in Caenorhabditis elegans is mediated by the 5'-to-3' exoribonuclease XRN2, also known as Rat1p. In plants, SDN (small RNA degrading nuclease)...

towards the bound RNA polymerase II. This exonuclease is XRN2 (5'-3' Exoribonuclease 2) in humans. This model proposes that XRN2 proceeds to degrade the...

RNase D is one of the seven exoribonucleases identified in E. coli. It is a 3'-5' exoribonuclease which has been shown to be involved in the 3' processing...

dumbbell element (DB), cis-acting replication element (CRE) and the exoribonuclease-resistant RNA elements (xrRNA). Further, unique elements have been...

incomplete degradation of genomic viral RNA by the host cells 5'-3' exoribonuclease 1 (XRN1). As the XRN1 degrades viral RNA, it stalls at stemloops formed...

the Nidoviruses. These viruses appear to have acquired a 3′-to-5′ exoribonuclease (ExoN) which has allowed for an increase in genome size. In 1972 Michael...

exosome while the 3' fragment is degraded from its 5' end by 5' -3' exoribonuclease 1(XRN1). Dissociation of the target mRNA strand from RISC after the...

viral RNA-dependent RNA polymerase and evades proofreading by viral exoribonuclease (ExoN), causing a decrease in viral RNA production. In some viruses...

further increasing specificity. A member of the larger DEDD family of exoribonucleases, RNAse T plays a key role in the maturation of tRNA as well as the...

2 (6p21.33) DHX16: DEAH-box helicase 16 (6p21.33) DOM3Z: Decapping exoribonuclease (6p21.33) DSP: Desmoplakin gene linked to cardiomyopathy (6p24.3) ELOVL5:...

for enriching 2'-O-Methylations guided by C/D snoRNAs by using RNA exoribonuclease (Mycoplasma genitalium RNase R, MgR) and periodate oxidation reactivity...

initiated by the removal of the 5’ cap followed by degradation by XRN1, an exoribonuclease enzyme. The other pathway by which mRNA is degraded is by deadenylation...

Ribonuclease II may refer to one of two enzymes: Ribonuclease T2 Exoribonuclease II This set index page lists enzyme articles associated with the same...

is that some members of the order Nidovirales encode proofreading exoribonuclease activity as part of a protein that is distinct from RdRp. Excluding...

large nidoviruses encode both a 2'-O-methyltransferase and a 3'–5' exoribonuclease (ExoN)—the latter being very unusual for an RNA virus. They also encode...

nidovirus lineages, also lack methyltransferases as well as a proofreading exoribonuclease, a domain that is conserved in nidoviruses with larger genomes. This...

producing 5'-phosphomonoesters EC 3.1.13: Exoribonucleases producing 5'-phosphomonoesters EC 3.1.14: Exoribonucleases producing 3'-phosphomonoesters EC 3.1...