• Thumbnail for Fibroblast growth factor 1
    growth factor (aFGF), is a growth factor and signaling protein encoded by the FGF1 gene. It is synthesized as a 155 amino acid polypeptide, whose mature form...
    20 KB (2,311 words) - 22:01, 16 July 2024
  • related signaling molecules: Members FGF1 through FGF10 all bind fibroblast growth factor receptors (FGFRs). FGF1 is also known as acidic fibroblast growth...
    25 KB (3,123 words) - 20:10, 26 April 2024
  • Erythropoietin (EPO) Fibroblast growth factor (FGF) Fibroblast growth factor 1(FGF1) Fibroblast growth factor 2(FGF2) Fibroblast growth factor 3(FGF3) Fibroblast...
    10 KB (1,131 words) - 19:14, 31 March 2024
  • Thumbnail for Type 2 diabetes
    rodents by a single intrahypothalamic infusion of Fibroblast Growth Factor 1 (FGF1), an effect that persists for months even in severely diabetic animals. This...
    113 KB (12,159 words) - 17:06, 29 July 2024
  • Thumbnail for Secretion
    evolve into lysosomes, which have a pH of 4.8. There are many proteins like FGF1 (aFGF), FGF2 (bFGF), interleukin-1 (IL1) etc. which do not have a signal...
    25 KB (2,981 words) - 05:27, 17 June 2024
  • cases, the FGFs themselves can also activate more than one receptor (i.e., FGF1, which binds all seven principal FGFRs). FGF7, however, can only activate...
    8 KB (827 words) - 22:08, 3 December 2023
  • HGNC:19125 Q96M96 5629 FGD5 HGNC:19117 Q6ZNL6 5630 FGD6 HGNC:21740 Q6ZV73 5631 FGF1 HGNC:3665 P05230 5632 FGF2 HGNC:3676 P09038 5633 FGF3 HGNC:3681 P11487 5634...
    277 KB (17 words) - 15:46, 9 May 2024
  • Thumbnail for Paracrine signaling
    FGFR Knockout Gene Survival Phenotype Fgf1 Viable Unclear Fgf3 Viable Inner ear, skeletal (tail) differentiation Fgf4 Lethal Inner cell mass proliferation...
    46 KB (4,967 words) - 21:12, 7 July 2024
  • Thumbnail for FGFBP1
    humans is encoded by the FGFBP1 gene. FGFBP1, or HBP17, binds to both acidic FGF1 and basic FGF2 fibroblast growth factors in a reversible manner. It also...
    7 KB (800 words) - 22:39, 8 June 2024
  • to induce mitosis in adult mammalian cardiomyocytes, while treatment with FGF1 and p38 MAP kinase inhibitors was found to regenerate the heart, reduce scarring...
    56 KB (6,677 words) - 20:18, 3 August 2024
  • Thumbnail for FGF-1 internal ribosome entry site (IRES)
    Predicted secondary structure and sequence conservation of IRES_FGF1 Identifiers Symbol IRES_FGF1 Rfam RF00387 Other data RNA type Cis-reg; IRES Domain(s) Eukaryota...
    2 KB (121 words) - 17:13, 16 July 2024
  • Thumbnail for Fibroblast growth factor receptor 2
    craniosynostosis. Fibroblast growth factor receptor 2 has been shown to interact with FGF1. The spliced isoforms, however differ in binding: FGFR2IIIb binds to FGF-1...
    14 KB (1,745 words) - 09:02, 15 July 2024
  • Thumbnail for Astrocyte
    (September 2021). "Role of hypothalamic MAPK/ERK signaling and central action of FGF1 in diabetes remission". iScience. 24 (9): 102944. Bibcode:2021iSci...24j2944B...
    81 KB (9,291 words) - 11:24, 9 July 2024
  • Thumbnail for Chromosome 5
    FBXL7: F-box/LRR-repeat protein 7 FCHSD1: FCH and double SH3 domain protein 1 FGF1: fibroblast growth factor 1 (acidic fibroblast growth factor) FGFR4: fibroblast...
    32 KB (2,298 words) - 22:55, 28 March 2024
  • Thumbnail for Fibroblast growth factor receptor 3
    v t e PDB gallery 1ry7: Crystal Structure of the 3 Ig form of FGFR3c in complex with FGF1...
    17 KB (1,847 words) - 09:39, 15 July 2024
  • Thumbnail for Fibroblast growth factor receptor 1
    bind to and activate one or more of the FGFRs: FGF1 to FGF10 and FGF16 to FGF23. Fourteen of these, FGF1 to FGF6, FGF8, FGF10, FGF17, and FGF19 to FGF23...
    44 KB (5,003 words) - 08:59, 15 July 2024
  • Thumbnail for Neuronal lineage marker
    acetyltransferase; Chox10; En1; Even-skipped/Eve; Evx1; Evx2; Fibroblast growth factor-1/FGF1; HB9; Isl1; Isl2; Lim3; Nkx6; p75 neurotrophin receptor; REG2; Sim1; SMI32;...
    37 KB (3,890 words) - 10:25, 22 June 2024
  • Thumbnail for FIBP
    isoforms have been found for this gene. FIBP has been shown to interact with FGF1. GRCh38: Ensembl release 89: ENSG00000172500 – Ensembl, May 2017 GRCm38:...
    4 KB (497 words) - 00:27, 4 March 2023
  • Thumbnail for CSNK2A2
    Activating transcription factor 2, ATF1, C-Fos, CREB binding protein, CSNK2B, FGF1, Nucleolin, PIN1, PTEN, and RELA. GRCh38: Ensembl release 89: ENSG00000070770...
    6 KB (691 words) - 05:52, 1 April 2024
  • Thumbnail for Casein kinase 2, alpha 1
    with: APC, ATF1, ATF2, C-Fos, C-jun, CDC25B, CHEK1, CREBBP, CSNK2B, DDIT3, FGF1, FGF2, HNRPA2B1 MAPK14, PIN1, PLEKHO1, PTEN, RELA, TAF1, and UBTF. GRCh38:...
    11 KB (1,175 words) - 04:55, 19 February 2024
  • Thumbnail for CSNK2B
    has been shown to interact with CD163, CSNK2A2, Casein kinase 2, alpha 1, FGF1, TRIB3, CDC34, Ribosomal protein L5, BTF3, BRCA1, RNF7, P70-S6 Kinase 1 and...
    19 KB (2,258 words) - 05:41, 19 February 2024
  • Thumbnail for Fibroblast growth factor receptor 4
    cancer. Fibroblast growth factor receptor 4 has been shown to interact with FGF1. GRCh38: Ensembl release 89: ENSG00000160867 – Ensembl, May 2017 GRCm38:...
    10 KB (1,291 words) - 09:08, 15 July 2024
  • Thumbnail for S100A13
    been found for this gene. S100A13 has been shown to interact with SYT1 and FGF1. Up-regulation of S100A13 was detected in cystic papillary thyroid carcinoma...
    10 KB (1,272 words) - 16:43, 5 January 2024
  • Thumbnail for HSPA9
    proliferation. It may also act as a chaperone. HSPA9 has been shown to interact with FGF1 and P53. In 2015, a group around Andrea Superti-Furga showed that biallelic...
    11 KB (1,308 words) - 19:15, 12 May 2024
  • Thumbnail for Homeobox protein MSX-1
    expressed in the early dental epithelium in mice such as Bmp4, Bmp7, Dlx2, Dlx5, Fgf1, Fgf2, Fgf4, Fgf8, Lef1, Gli2, and Gli3 are also potential candidates. Based...
    17 KB (2,178 words) - 20:15, 10 June 2023
  • mesenchyme or with a Matrigel artificially loaded with ramogens, such as GDNF and FGF1. The ramogens used in this study were manufactured with fresh mesenchyme...
    5 KB (656 words) - 21:04, 4 February 2023
  • Thumbnail for Mothers against decapentaplegic homolog 3
    cells. Some of the developmental genes regulated by this pathway include FGF1, NGF, and WNT11 as well as stem/progenitor cell associated genes CD34 and...
    33 KB (4,115 words) - 19:27, 8 July 2024
  • Thumbnail for MAPK14
    012. PMID 16889791. Engel FB, Hsieh PC, Lee RT, Keating MT (Oct 2006). "FGF1/p38 MAP kinase inhibitor therapy induces cardiomyocyte mitosis, reduces scarring...
    44 KB (5,265 words) - 05:22, 10 July 2024