Fibroblast growth factor 19 is a protein that in humans is encoded by the FGF19 gene. It functions as a hormone, regulating bile acid synthesis, with effects...
21 KB (2,570 words) - 20:54, 5 June 2024
negatively regulated by the ileal hormone fibroblast growth factor 19 (FGF19), and lower levels of this hormone result in overproduction of bile acids...
22 KB (2,533 words) - 03:53, 7 July 2024
Andersson, L; Andersson, G (November 2007). "Duplication of FGF3, FGF4, FGF19 and ORAOV1 causes hair ridge and predisposition to dermoid sinus in Ridgeback...
28 KB (3,123 words) - 21:03, 6 July 2024
functions are still being characterized. FGF15 is the mouse ortholog of human FGF19 (there is no human FGF15) and, where their functions are shared, they are...
25 KB (3,123 words) - 20:10, 26 April 2024
β-klotho, and γ-klotho. α-klotho activates FGF23, and β-klotho activates FGF19 and FGF21. When the subfamily is not specified, the word "klotho" typically...
36 KB (3,786 words) - 16:44, 13 February 2024
mouse; FGF19 was found in humans and other species. They share physiological functions and so are often referred to as FGF15/19 or as FGF15/FGF19. They...
2 KB (257 words) - 04:30, 5 April 2024
Aldafermin is a fibroblast growth factor 19 (FGF19) analogue developed for non-alcoholic steatohepatitis. Babu, A.F.; Iannone, V.; Lok, J.; Gomez-Gallego...
6 KB (366 words) - 04:42, 26 February 2024
fibroblast growth factor (FGF) family but, like FGF19, FGF21 and FGF23, has endocrine functions. FGF19 is the orthologous protein in humans. They are often...
6 KB (748 words) - 00:41, 6 December 2023
median levels of FGF19, an ileal hormone that regulates increased hepatic bile acid synthesis, have been found in this condition. FGF19 is potently stimulated...
19 KB (1,825 words) - 22:02, 12 July 2024
17(FGF17) Fibroblast growth factor 18(FGF18) Fibroblast growth factor 19(FGF19) Fibroblast growth factor 20(FGF20) Fibroblast growth factor 21(FGF21) Fibroblast...
10 KB (1,131 words) - 19:14, 31 March 2024
HGNC:3672 O43320 5646 FGF17 HGNC:3673 O60258 5647 FGF18 HGNC:3674 O76093 5648 FGF19 HGNC:3675 O95750 5649 FGF20 HGNC:3677 Q9NP95 5650 FGF21 HGNC:3678 Q9NSA1...
277 KB (17 words) - 15:46, 9 May 2024
during absorption in the intestine increases transcription and synthesis of FGF19, which then inhibits bile acid synthesis in the liver. Emerging evidence...
36 KB (4,587 words) - 11:12, 7 July 2024
transcription of many genes is activated by FXR, including those encoding FGF19 and small heterodimer partner. CDCA has been used as medical therapy to...
10 KB (836 words) - 19:53, 29 June 2024
bile acid diarrhea associated with impaired negative feedback of CYP7A1 by FGF19. Russell DW (2003). "The enzymes, regulation, and genetics of bile acid...
4 KB (365 words) - 22:44, 17 December 2023
discovered two new signaling pathways mediated by the endocrine factors FGF19 and FGF21, which has become a significant accomplishment in the field. He...
2 KB (140 words) - 13:47, 23 June 2023
discovered two new signaling pathways mediated by the endocrine factors FGF19 and FGF21, which has become a significant accomplishment in the field. "Steven...
2 KB (124 words) - 19:05, 26 July 2022
Andersson, Leif; Andersson, Göran (November 2007). "Duplication of FGF3, FGF4, FGF19 and ORAOV1 causes hair ridge and predisposition to dermoid sinus in Ridgeback...
82 KB (9,474 words) - 03:14, 19 May 2024
Kharitonenkov, Alexei; DiMarchi, Richard D. (2018-07-01). "Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificity". Molecular Metabolism...
24 KB (2,468 words) - 22:40, 28 December 2023
FGF16 to FGF23. Fourteen of these, FGF1 to FGF6, FGF8, FGF10, FGF17, and FGF19 to FGF23 bind and activate FGFR1. FGFs binding to FGFR1 is promoted by their...
44 KB (5,001 words) - 17:06, 4 January 2024
WE (December 2011). "Short hairpin RNA screen indicates that Klotho beta/FGF19 protein overcomes stasis in human colonic epithelial cells". The Journal...
3 KB (334 words) - 02:00, 4 March 2023