Ferroxidase also known as Fe(II):oxygen oxidoreductase is an enzyme that catalyzes the oxidization of iron II to iron III: 4 Fe2+ + 4 H+ + O2 ⇔ 4 Fe3+...

Ceruloplasmin (or caeruloplasmin) is a ferroxidase enzyme that in humans is encoded by the CP gene. Ceruloplasmin is the major copper-carrying protein...

caused by impaired iron transport. Hephaestin is a copper-containing ferroxidase enzyme located in the duodenal mucosa that oxidizes iron and facilitates...

all subunits of bacterial and archaeal ferritin are H-type and have ferroxidase activity, which means they are able to convert iron from the ferrous...

Aceruloplasminemia is a rare autosomal recessive disorder in which the liver can not synthesize the protein ceruloplasmin properly, which is needed to...

of iron and possibly copper. It is a transmembrane copper-dependent ferroxidase responsible for transporting dietary iron from intestinal enterocytes...

Ferritin heavy chain is a ferroxidase enzyme that in humans is encoded by the FTH1 gene. FTH1 gene is located on chromosome 11, and its mutation causes...

; Rogers, Jack T.; Bush, Ashley I. (September 8, 2010). "Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's...

that APP has ferroxidase activity in its E2 domain and facilitates export of Fe(II) is possibly incorrect since the proposed ferroxidase site of APP located...

the only known iron exporter in mammals, ferroportin. Hephaestin, a ferroxidase that can oxidize Fe2+ to Fe3+ and is found mainly in the small intestine...

Mitochondrial ferritin is a ferroxidase enzyme that in humans is encoded by the FTMT gene. It is classified as a metal-binding protein which is located...

Although the ferritin light chain unlike the ferritin heavy chain has no ferroxidase activity, the light chain may be responsible for the electron transfer...

substrate. Multicopper oxidases include: Ceruloplasmin EC 1.16.3.1 (ferroxidase), a 6-domain enzyme found in the serum of mammals and birds that oxidizes...

the only known iron exporter in mammals, ferroportin. Hephaestin, a ferroxidase that can oxidize Fe2+ to Fe3+ and is found mainly in the small intestine...

Malicdan, May Christine V. (2019-05-24). "Biallelic HEPHL1 variants impair ferroxidase activity and cause an abnormal hair phenotype". PLOS Genetics. 15 (5)...

maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin). Hemochromatosis SLC2A4 P14672 Insulin-regulated...

four major helices of the subunit, which has been identified as the ferroxidase active site. Bfr from Pseudomonas aeruginosa (PaBfr), unlike other Bfrs...

Krutika; Leong, Su Ling; Perez, Keyla; et al. (2010). "Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein is Inhibited by Zinc in Alzheimer's...

activity ferrous iron binding metal ion binding ferric iron binding ferroxidase activity Cellular component cytoplasm cytosol mitochondrial matrix mitochondrion...

at the characteristic, highly conserved intersubunit ferroxidase center. The dinuclear ferroxidase centers are located at the interfaces between subunits...

ferric-chelate reductase [NAD(P)H] * *No Wikipedia article EC 1.16.3.1: ferroxidase EC 1.16.3.2: bacterial non-heme ferritin * EC 1.16.3.3: manganese oxidase...

rebound to be transported across the membrane again via both Cu-dependent ferroxidase and Fe(III) transport proteins. Alternatively, ferrous, unchelated iron...

pathway in Saccharomyces cerevisiae, which consists of a multicopper ferroxidase (Fet3) and an iron plasma permease (FTR1) has a high affinity for iron...

≈ 0.1 μM) Fe2+ uptake systems. These systems depend on cell surface ferroxidases to convert extracellular Fe2+ to Fe3+ which can then be taken up via...

ferritin-like proteins as cargo. The operons usually include genes for ferroxidase enzymes, critical for iron oxidation. They belong to the Pfam family...

Giuseppe D.; Rogers, Jack T.; Bush, Ashley I. (2010). "Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's...

(Nexo) and the carboxyl terminus in the cytoplasm (Ccyt). Part of the ferroxidase reaction, Fet3p catalyzes the oxidation of Fe(II) to Fe(III) using O2...

is vital for the subsequent insertion of copper into ceruloplasmin, a ferroxidase required for iron metabolism, within the golgi apparatus. In addition...