Galectins are a class of proteins that bind specifically to β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3GlcNAc or Galβ1-4GlcNAc), which...

Galectin-3 is a protein that in humans is encoded by the LGALS3 gene. Galectin-3 is a member of the lectin family, of which 14 mammalian galectins have...

Galectin-9 was first isolated from mouse embryonic kidney in 1997 as a 36 kDa beta-galactoside lectin protein. Human galectin-9 is encoded by the LGALS9...

Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. LGALS1 contains four exons. The galectin-1 protein is 135 amino acids in length and...

Galectin-7 is a protein that in humans is encoded by the LGALS7 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating...

Galectin-8 is a protein of the galectin family that in humans is encoded by the LGALS8 gene. This gene encodes a member of the galectin family. Galectins...

Galectin-4 is a protein that in humans is encoded by the LGALS4 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating...

Belapectin (also known as GR-MD-02) is a galectin-3 inhibitor developed by Galectin Therapeutics that is in clinical trials for the treatment of non-alcoholic...

Galectin-2 is a protein that in humans is encoded by the LGALS2 gene. The protein encoded by this gene is a soluble beta-galactoside binding lectin. The...

involved in response to lysosomal damage, often directed by galectins such as galectin-3 and galectin-8. One of the mechanisms of programmed cell death (PCD)...

Charcot–Leyden crystals are microscopic crystals composed of eosinophil protein galectin-10 found in people who have allergic diseases such as asthma or parasitic...

July 1, 2013. In 2021, Carson joined Galectin Therapeutics to assist with development of the company's galectin-3 inhibitor, belapectin, as a treatment...

Galectin-3-binding protein is a protein that in humans is encoded by the LGALS3BP gene. The galectins are a family of beta-galactoside-binding proteins...

Galectin-10 is an enzyme that in humans is encoded by the CLC gene. Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional...

factor-2 (Lect2) Insulin amyloidosis Insulin Galectin-7 amyloidosis (primary localized cutaneous amyloidosis) Galectin-7 (Gal7) Corneodesmosin amyloidosis Corneodesmosin...

fibrosis, cancer and inflammation. The company was founded in 2011 by leading galectin scientists and biotech executives from Sweden, United Kingdom, and Denmark...

Selvigaltin (GB1211) is the first small-molecule, orally delivered galectin-3 inhibitor to be discovered. It is developed by Galecto Biotech, which is...

glycolysis in these tumors is probably related to their aggressive biology. Galectin-1 in TNBC is a beta-galactosidase-binding protein that shields cancer cells...

oligodendrocytes or neuronal cells that secreted neuroprotective factors. Galectin-1 is expressed in adult NSCs and has been shown to have a physiological...

confirmed to be within the venom are cystatins, peroxiredoxin and galectin. Galectin induces cell death in its victims and cystatins inhibit defense enzymes...

TB006 is a humanized monoclonal antibody targeting galectin-3, which is suspected to be a factor in the formation of amyloid plaques. Cummings, Jeffrey...

MH, Kimura T, et al. (October 2016). "TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis"...

binding site is lack of key residue for binding beta-galactoside. It is a galectin-like protein. The ligand of this protein is still unknown. PP13 levels...

thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit HSPC159: Galectin-related protein ID2-AS1: encoding protein Id2 antisense rna 1 (head to...

Andrea; Carpi, Federico; Mechanick, Jeffrey I.; Bartolazzi, Armando (2010). "Galectin-3 detection on large-needle aspiration biopsy improves preoperative selection...

of the following main elements: collagen, fibronectin-like molecules, galectin, and a minor component, dermatopontin. These polypeptides form the extracellular...

glycan-binding sites is recognizes by carbohydrate domain of another ligands galectin-9 (Gal-9). The mucin domain is variable in a member of the TIM family,...

of P. pulmonarius may slow the proliferation of cancer cells with high galectin-3 levels, while at the same time downregulate tumour cell adherence – which...

how such tumors can be regressed. He also looked at the properties of galectins, and how they show potential for disease. Rabinovich was born in Córdoba...

chemically induced colitis and augments inflammatory responses through galectin-3". The Journal of Infectious Diseases. 197 (7): 972–980. doi:10.1086/528990...