• cyclic nucleotide–gated (HCN) channels are integral membrane proteins that serve as nonselective voltage-gated cation channels in the plasma membranes...
    14 KB (1,568 words) - 21:13, 10 September 2024
  • HCN may refer to: HCN channel, a cellular ion channel Highly composite number, a type of integer Hydrogen cyanide, The toxic gas HCN Halcyonair, a Cape...
    503 bytes (81 words) - 16:15, 15 May 2024
  • Thumbnail for Cardiac action potential
    be due to a group of channels, referred to as HCN channels (Hyperpolarization-activated cyclic nucleotide-gated). These channels open at very negative...
    46 KB (5,430 words) - 18:10, 24 April 2024
  • electric current in the heart that flows through the HCN channel or pacemaker channel. Such channels are important parts of the electrical conduction system...
    10 KB (1,195 words) - 21:33, 8 November 2023
  • Thumbnail for Sinoatrial node
    hyperpolarisation-activated cyclic nucleotide–gated (HCN) channels. The activation of ion channels at very negative membrane potentials is unusual, therefore...
    24 KB (2,805 words) - 14:22, 17 October 2024
  • Thumbnail for Cyclic nucleotide–gated ion channel
    interface between the channel and bilayer. The molecular mechanism of DAG inhibition is still not fully understood. Ion channel HCN channel Voltage-dependent...
    39 KB (4,913 words) - 23:11, 11 January 2024
  • blockers such as metoprolol Acetylcholine Digoxin Pacemaker current (i.e. HCN channel) inhibitors (e.g. ivabradine) Alboni, P.; Menozzi, C.; Brignole, M.;...
    3 KB (286 words) - 17:41, 30 March 2024
  • Thumbnail for Prefrontal cortex
    alpha-2A adrenergic receptor. A downstream target of this drug, the HCN channel, is one of the most recent areas of exploration in prefrontal cortex...
    47 KB (5,358 words) - 15:16, 25 September 2024
  • hyperpolarization-activated, cyclic nucleotide-gated (HCN) channels, the molecular components of "funny" channels cloned in the late 90's, are today known to play...
    25 KB (2,620 words) - 10:56, 5 January 2024
  • Thumbnail for Thermoreceptor
    as various voltage-sensitive channels including the hyperpolarization-activated, cyclic nucleotide-gated (HCN) channel and the rapidly activating and...
    10 KB (1,289 words) - 16:43, 15 October 2024
  • Thumbnail for Pyramidal cell
    as FREM3 type and often have a high amount of Ih-current generated by HCN-channel. Pyramidal neurons are the primary neural cell type in the corticospinal...
    25 KB (2,394 words) - 11:33, 10 November 2024
  • Thumbnail for HCN4
    HCN4 (category Ion channels)
    cyclic nucleotide-gated channel 4 is a protein that in humans is encoded by the HCN4 gene. There are four HCN channels. HCN4 is prominently expressed...
    11 KB (1,313 words) - 00:06, 18 August 2023
  • sodium channels ability to be opened, however, because the neuron is more negative it becomes more difficult to reach the action potential threshold. HCN channels...
    9 KB (1,082 words) - 16:15, 20 November 2024
  • Thumbnail for Alpha-2 adrenergic receptor
    Alpha2A-adrenoceptors strengthen working memory networks by inhibiting cAMP-HCN channel signaling in prefrontal cortex. Cell 129: 397–410, 2007. Guanfacine's...
    25 KB (2,231 words) - 17:54, 18 September 2024
  • Thumbnail for Guanfacine
    α2A-adrenoceptors. Cyclic adenosine monophosphate (cAMP)-mediated opening of HCN and KCNQ channels is inhibited, which enhances prefrontal cortical synaptic connectivity...
    43 KB (3,962 words) - 04:55, 24 October 2024
  • Thumbnail for Cyclic adenosine monophosphate
    regulation of ion channels called hyperpolarization-activated cyclic nucleotide-gated channels (HCN). When cAMP stimulates the HCN, the channels open, This research...
    16 KB (1,612 words) - 20:19, 27 October 2024
  • Thumbnail for Ion channel
    the cyclic nucleotide-gated (CNG) channels and the hyperpolarization-activated, cyclic nucleotide-gated (HCN) channels. This grouping is functional rather...
    46 KB (5,308 words) - 19:08, 1 November 2024
  • Thumbnail for Potassium channel
    Potassium channels are the most widely distributed type of ion channel found in virtually all organisms. They form potassium-selective pores that span...
    57 KB (5,834 words) - 05:50, 10 October 2024
  • Thumbnail for Afterhyperpolarization
    AHPs are not yet well understood, but may also involve M current and HCN channels for medium AHPs, and ion-dependent currents and/or ionic pumps for slow...
    5 KB (611 words) - 23:16, 23 July 2021
  • Voltage-gated calcium channels (VGCCs), also known as voltage-dependent calcium channels (VDCCs), are a group of voltage-gated ion channels found in the membrane...
    28 KB (3,091 words) - 08:22, 19 October 2024
  • reaction force Gs alpha subunit Gunther O. Hofmann HCN1 HCN2 HCN3 HCN4 HCN channel HERG HTR3A HTR3B HTR3C HTR3D HTR3E HVCN1 Hal Anger Hans Frauenfelder...
    15 KB (1,545 words) - 18:32, 17 August 2024
  • Thumbnail for Medial septal nucleus
    interneurons express hyperpolarization-activated cyclic nucleotide-gated (HCN) channels which likely, at least partially, mediate their pacemaker properties...
    2 KB (224 words) - 02:20, 17 December 2020
  • Thumbnail for Sodium channel
    Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's membrane. They belong to the superfamily...
    51 KB (5,600 words) - 16:44, 18 September 2024
  • Thumbnail for Ligand-gated ion channel
    Ligand-gated ion channels (LICs, LGIC), also commonly referred to as ionotropic receptors, are a group of transmembrane ion-channel proteins which open...
    29 KB (2,597 words) - 03:43, 7 April 2024
  • Thumbnail for HCN1
    nucleotide-gated channel 1 is a protein that in humans is encoded by the HCN1 gene. Hyperpolarization-activated cation channels of the HCN gene family, such...
    13 KB (1,478 words) - 04:31, 16 June 2023
  • List of television stations in Mississippi (category Lists of television channels in the United States)
    Greenwood The Gospel Broadcasting Network - GBN - Olive Branch HCN (Hill Country Network) - HCN - New Albany Mississippi media List of newspapers in Mississippi...
    16 KB (244 words) - 09:49, 26 July 2024
  • Thumbnail for Inward-rectifier potassium channel
    Inward-rectifier potassium channels (Kir, IRK) are a specific lipid-gated subset of potassium channels. To date, seven subfamilies have been identified...
    22 KB (2,007 words) - 01:49, 26 March 2024
  • K+-selective ion channels. The consequential hyperpolarization activates hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels. The depolarizing...
    29 KB (3,524 words) - 17:01, 4 January 2024
  • Thumbnail for Muscimol
    Ayyıldız M, Ağar E (March 2024). "The role of HCN channels on the effects of T-type calcium channels and GABAA receptors in the absence epilepsy model...
    37 KB (3,825 words) - 21:25, 7 October 2024
  • Thumbnail for Cation channel superfamily
    potassium, calcium, ryanodine receptor, HCN, CNG, CatSper, and TRP channels. This large group of ion channels apparently includes families 1.A.1, 1.A...
    19 KB (1,692 words) - 03:53, 29 November 2023