Haptens (derived from the Greek haptein, meaning “to fasten”) are small molecules that elicit an immune response only when attached to a large carrier...

hapten. Haptens are low-molecular-weight compounds that may be bound by antibodies, but cannot elicit an immune response. Consequently, the haptens themselves...

lysine residues for coupling haptens allows a high hapten:carrier protein ratio, increasing the likelihood of generating hapten-specific antibodies. In addition...

compound lacked hapten characteristics, a hapten feature of a drug metabolite as cause for the DHR was postulated. Importantly, the hapten theory as explanation...

[3.2.1] octane-2-carboxamido-hexanoic acid Cocaine haptens that create catalytic anti-bodies require transitional states as affected...

Instead, it attaches to certain proteins of the skin, where it acts as a hapten, leading to a type IV hypersensitivity reaction.[self-published source?]...

containing two nitro functional groups attached to a phenyl ring. It is a hapten used in vaccine preparation. Dinitrophenyl does not elicit any immune response...

hybridization to mRNA with oligonucleotide and RNA probes (both radio-labeled and hapten-labeled), analysis with light and electron microscopes, whole mount in situ...

Antigenicity is the capacity of a chemical structure (either an antigen or hapten) to bind specifically with a group of certain products that have adaptive...

oak, or poison sumac. Urushiol, which is not itself a protein, acts as a hapten and chemically reacts with, binds to, and changes the shape of integral...

[citation needed] There are two models for this: the hapten model and the autoantibody model. The hapten model proposes that certain drugs, especially penicillin...

water-soluble analog, Sulfo-SMCC, is commonly used to prepare antibody-hapten conjugates for antibody development. An in-vitro cross-linking method is...

new members were recruited: Christoffer Nilsson to play drums and Annika Haptén, a singer. Later that summer, Staffan Franzén was officially announced as...

discriminate among specific epitopes present on the antigen surface. A hapten is a small molecule that can only induce an immune response when attached...

Dextran 1 is a hapten inhibitor that greatly reduces the risk for anaphylactic reactions when administering dextran. Dextran 1 is composed of a small fraction...

large molecules found on the surfaces of pathogens, but can also be small haptens (such as penicillin) attached to carrier molecule. Each lineage of B cell...

isotope labeling, and tagging the base with a hapten and detecting chromogenically with an anti-hapten antibody-enzyme conjugate (e.g., via an ELISA format)...

This is a known allergen that becomes bound to plasma proteins, creating a hapten-protein complex – a signature mechanism in true IgE drug allergy and true...

molecule has been associated with two significant adverse effects: the hapten or immune response. This immune response, also known as agranulocytosis...

diphtheria toxin, currently used as a carrier protein for polysaccharides and haptens to make them immunogenic. There is some dispute about the toxicity of CRM197...

from the U.S. National Institute on Drug Abuse. NicVAX consists of the hapten 3'-aminomethylnicotine which has been conjugated (attached) to Pseudomonas...

Kalish, J. A. Wood & A. LaPorte (1994). "Processing of urushiol (poison ivy) hapten by both endogenous and exogenous pathways for presentation to T cells in...

Guanche language Guidance, navigation, and control, in aeronautics A cocaine hapten analog This disambiguation page lists articles associated with the title...

NicVAX, which aims to vaccinate against nicotine using a chemically modified hapten version linked to exotoxin A TA-CD, cocaine linked to inactivated cholera...

cause the development of HIT antibodies, suggesting heparin may act as a hapten, thus may be targeted by the immune system. In HIT, the immune system forms...

cocktail developed by Ventana Medical Systems. The DDISH (Dual-chromagen/Dual-hapten In-situ hybridization) cocktail uses both HER2 and Chromosome 17 hybridization...

Weizmann Institute of Science Thesis Kinetic and thermodynamic studies of hapten induced conformational changes in immunoglobulins  (1978) Academic advisors...

apoptosis. New methods incorporate the dUTPs modified by fluorophores or haptens, including biotin or bromine, which can be detected directly in the case...

different individuals, combine with epithelial-derived proteins, forming haptens which bind with Langerhans cells in the mucosa, which in turn present the...

metabolite, penicilloic acid, which reacts with proteins and serves as a hapten to cause an immune reaction. Approximately five percent of patients have...