The Hayflick limit, or Hayflick phenomenon, is the number of times a normal somatic, differentiated human cell population will divide before cell division...

This is known as the Hayflick limit. His discoveries overturned a 60-year old dogma that all cultured cells are immortal. Hayflick demonstrated that normal...

Hayflick limit on how many times they can divide. Biologists chose the word "immortal" to designate cells that are not subject to the Hayflick limit,...

species have an upper limit on the number of times somatic cells not expressing telomerase can divide. This is called the Hayflick limit, although this number...

species possess 'biological immortality' due to an apparent lack of the Hayflick limit. Some scientists, futurists and philosophers have theorized about the...

for the Hayflick limit, which specifies the number of times a normal human cell population will divide before cell division stops. Hayflick's discovery...

some point the progeny reach their Hayflick limit, which is believed to be between 50 and 70 cell divisions. At the limit the cells become senescent and cell...

cellular division was first observed by Leonard Hayflick, and is now referred to as the Hayflick limit. Significant discoveries were subsequently made...

senescent. This process is known as "replicative senescence", or the Hayflick limit. Hayflick's discovery of mortal cells paved the path for the discovery and...

Elongation of telomeres by epitalon was sufficient to surpass the Hayflick limit in a cell culture of human fetal fibroblast cells, extending their proliferative...

before the DNA loss prevents further division. (This is known as the Hayflick limit.) Within the germ cell line, which passes DNA to the next generation...

as the Hayflick limit. Once this limit has been reached, more cells die than can be replaced in the same time span. Thus, soon after this limit is reached...

theory of aging Eternal youth Facial rejuvenation Fountain of Youth Hayflick Hayflick limit Immortality Indefinite lifespan Kayakalpa Life extension Maximum...

Carnosine is considered as a geroprotector. Carnosine can increase the Hayflick limit in human fibroblasts, as well as appearing to reduce the telomere shortening...

would otherwise become postmitotic and undergo apoptosis to exceed the Hayflick limit and become potentially immortal, as is often the case with cancerous...

program, the Hayflick limit, that limits their multiplication to about 60–70 doublings, at which point they reach a stage of senescence. This limit can be overcome...

aging and eventual cell death. In this way, the cells circumvent the Hayflick limit, which is the limited number of cell divisions that most normal cells...

probes per cubic parsec) or arbitrary limit (such as ten million within one century), analogous to the Hayflick limit in cell reproduction. One problem with...

and Leonard Hayflick, known for discovering that human cells divide for a limited number of times in vitro (called the Hayflick limit). In 2017, Geron...

In humans this occurs, on average, after 52 divisions, known as the Hayflick limit. The cell is then referred to as senescent. With each division the cells...

aging. 1961 Discovery by Leonard Hayflick of the limit of divisions for somatic cells, named the Hayflick limit. Hayflick found that normal human cells,...

undergo partial degradation each time a cell undergoes division (see Hayflick limit). In contrast, quiescence is a reversible state of cellular dormancy...

literary competition. Tierney is the author of the full collections The Hayflick Limit, Full Speed Through the Morning Dark, Probably Inevitable, Midday at...

Telomerases are necessary to sustain cell division unrestricted by the Hayflick limit of ~50 cell divisions. hESCs express high telomerase activity to sustain...

doublings while generally retaining their viability (described as the Hayflick limit). Aside from temperature and gas mixture, the most commonly varied factor...

successfully replicated. In the 1960s, Leonard Hayflick and Paul Moorhead proposed the concept of the Hayflick limit, which states that differentiated cells...

telomeres, to protect their DNA and extend their cell division limit (the Hayflick limit). Potency specifies the differentiation potential (the potential...

evidence for the Big Bang 1965: Leonard Hayflick: normal cells divide only a certain number of times: the Hayflick limit 1967: Jocelyn Bell Burnell and Antony...

about 50 cell divisions in laboratory culture (the Hayflick Limit, discovered by Leonard Hayflick in 1961). Hearing loss with age (presbycusis) Teenagers...

Gene mutation theory Genetic control theory Glycation theory of aging Hayflick limit theory Inflammation theory of aging Immunological theory of aging Log-normal...