Heparin, also known as unfractionated heparin (UFH), is a medication and naturally occurring glycosaminoglycan. Heparin is a blood anticoagulant that...
78 KB (7,865 words) - 12:25, 1 July 2024
Heparin-induced thrombocytopenia (HIT) is the development of thrombocytopenia (a low platelet count), due to the administration of various forms of heparin...
23 KB (2,552 words) - 17:15, 15 February 2024
Low-molecular-weight heparin (LMWH) is a class of anticoagulant medications. They are used in the prevention of blood clots and, in the treatment of venous...
27 KB (3,060 words) - 19:12, 6 May 2024
aggregated platelet products. Common anticoagulants include warfarin and heparin. The use of anticoagulants is a decision based on the risks and benefits...
78 KB (8,717 words) - 21:24, 13 July 2024
2008 Chinese heparin adulteration, refers to heparin adulteration incidents that occurred in the United States of America in 2008. Pharmaceutical company...
7 KB (767 words) - 18:27, 31 January 2024
Heparan sulfate (redirect from Heparin sulfate)
to heparin. Both consist of a variably sulfated repeating disaccharide unit. The main disaccharide units that occur in heparan sulfate and heparin are...
36 KB (4,151 words) - 06:37, 27 May 2024
The enzyme heparin lyase (EC 4.2.2.7) catalyzes the following process: Eliminative cleavage of polysaccharides containing (1→4)-linked D-glucuronate or...
1 KB (132 words) - 14:26, 26 August 2023
Antithrombin (section Antithrombin and heparin)
β-antithrombin. Its activity is increased manyfold by the anticoagulant drug heparin, which enhances the binding of antithrombin to factor IIa (thrombin) and...
45 KB (5,331 words) - 23:48, 9 March 2024
Oxygenator (redirect from Heparin-coated blood oxygenator)
uncoated CPB circuits require a high dose of systemic heparin. Although the effects of heparin are reversible by administering protamine, there are a...
9 KB (1,145 words) - 06:07, 26 November 2023
Petr Zelenka (serial killer) (redirect from Heparin killer)
others between May and December, 2006. He killed with a hidden vial of heparin — a blood-thinning drug causing internal bleeding when administered in...
2 KB (157 words) - 18:42, 25 June 2024
Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of proteins that in humans is encoded by the HBEGF gene. HB-EGF-like growth...
20 KB (2,598 words) - 16:38, 26 June 2024
effects of heparin. It is specifically used in heparin overdose, in low molecular weight heparin overdose, and to reverse the effects of heparin during delivery...
14 KB (1,419 words) - 18:49, 28 June 2024
Pleiotrophin (redirect from Heparin affin regulatory peptide)
known as heparin-binding brain mitogen (HBBM) or heparin-binding growth factor 8 (HBGF-8) or neurite growth-promoting factor 1 (NEGF1) or heparin affinity...
14 KB (1,649 words) - 07:53, 21 December 2023
The enzyme heparin-sulfate lyase (EC 4.2.2.8) catalyzes the chemical reaction Elimination of sulfate; appears to act on linkages between N-acetyl-D-lucosamine...
1 KB (115 words) - 14:26, 26 August 2023
Enoxaparin sodium (category Heparins)
appears to be safe for the baby. Enoxaparin is in the low molecular weight heparin family of medications. Enoxaparin was first made in 1981 and approved for...
22 KB (1,681 words) - 16:41, 6 July 2024
restore the level of clotting factors in the blood, as well as platelets and heparin to prevent further thrombi formation.[citation needed] A thrombus occurs...
21 KB (2,276 words) - 05:36, 25 June 2024
Administration (FDA) for prophylaxis or treatment of thrombosis in people with heparin-induced thrombocytopenia (HIT). In 2002, it was approved for use during...
7 KB (380 words) - 05:41, 13 July 2024
site due to their anticoagulant effect. This includes heparin and low molecular weight heparin products such as enoxaparin. There is some low certainty...
22 KB (2,581 words) - 08:38, 3 December 2023
seepage and collection of blood may occur if heparin is given via an intramuscular route; to avoid this, heparin must be given intravenously or subcutaneously...
6 KB (620 words) - 23:04, 4 June 2024
Heparin mimicking polymers are synthetic compounds that possess similar characteristics to heparin, that is it can be used clinically as an anticoagulant...
5 KB (724 words) - 04:29, 2 September 2020
Taurolidine/heparin, sold under the brand name Defencath, is a fixed-dose combination catheter lock solution used for central venous catheter instillation...
7 KB (389 words) - 03:36, 10 January 2024
low-molecular-weight heparin (LMWH) or unfractionated heparin, or increasingly with direct acting oral anticoagulants (DOAC). Those initially treated with heparins can...
40 KB (4,613 words) - 02:51, 9 March 2024
Ram Sasisekharan (section Heparin crisis)
identified oversulfated chondroitin sulfate as a contaminant in the US heparin supply in 2007 and 2008, he had developed antibodies for dengue, yellow...
40 KB (3,965 words) - 14:35, 7 July 2024
Heparin cofactor II (HCII), a protein encoded by the SERPIND1 gene, is a coagulation factor that inhibits IIa, and is a cofactor for heparin and dermatan...
12 KB (1,455 words) - 17:08, 23 April 2024
like heparin, act by interacting with heparin binding proteins, generally through ionic interactions or hydrogen bonding. Some examples of heparin binding...
7 KB (884 words) - 16:14, 24 October 2023
Heparin necrosis is a cutaneous condition and usually occurs between days 5 and 10 of heparin therapy. Warfarin necrosis List of cutaneous conditions...
1 KB (49 words) - 11:09, 4 June 2024
suspended the manufacture of heparin, and launched an investigation. The investigation into the contamination has focused on raw heparin produced by one of Baxter's...
40 KB (3,743 words) - 16:27, 3 June 2024
Fondaparinux (category Heparins)
an anticoagulant medication chemically related to low molecular weight heparins. It is marketed by Viatris. A generic version developed by Alchemia is...
9 KB (711 words) - 10:19, 16 August 2023
who relapsed following splenectomy. Discontinuation of heparin is critical in a case of heparin-induced thrombocytopenia (HIT). Beyond that, however, clinicians...
28 KB (2,658 words) - 15:10, 6 January 2024
Intravenous therapy (redirect from Heparin lock)
or saline lock, a needleless connection filled with a small amount of heparin or saline solution to prevent clotting, between uses of the catheter. Ported...
60 KB (7,182 words) - 01:54, 30 March 2024