• Thumbnail for Hepatotoxicity
    Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease...
    39 KB (4,074 words) - 14:03, 4 October 2024
  • Thumbnail for Paracetamol poisoning
    inducer isoniazid increases the risk of hepatotoxicity, though whether 2E1 induction is related to the hepatotoxicity in this case is unclear. Concomitant...
    64 KB (7,235 words) - 16:23, 11 September 2024
  • Thumbnail for Kava
    addition to the kava lactones is important to provide protection against hepatotoxicity". It has also been argued that kavalactone extracts have often been...
    69 KB (7,678 words) - 03:57, 24 September 2024
  • Thumbnail for Cholestasis
    Cholestasis is a condition where the flow of bile from the liver to the duodenum is impaired. The two basic distinctions are: obstructive type of cholestasis...
    112 KB (12,705 words) - 07:14, 11 September 2024
  • Thumbnail for Troglitazone
    $136 million. Since the withdrawal in 2000, mechanisms of troglitazone hepatotoxicity have been extensively studied using a variety of in vivo, in vitro,...
    20 KB (2,044 words) - 13:18, 15 August 2024
  • published in the World Journal of Hepatology reexamined known cases of hepatotoxicity that had previously been linked to consumption of Herbalife products...
    88 KB (7,441 words) - 18:58, 30 September 2024
  • Thumbnail for Noni juice
    hepatotoxicity; however, an increasing number of subsequent case reports suggested that some individuals may be particularly sensitive to hepatotoxic...
    10 KB (1,054 words) - 04:05, 28 November 2023
  • for hepatotoxicity during drug metabolism with a number of different drugs, including flucloxacillin, troleandomycin, and troglitazone. Hepatotoxicity indicates...
    9 KB (928 words) - 07:29, 9 August 2024
  • Auclert, L; Le-Louët, H (November 2021). "Safety data and withdrawal of hepatotoxic drugs". Therapie. 76 (6): 715–723. doi:10.1016/j.therap.2018.02.004....
    45 KB (1,903 words) - 16:52, 9 October 2024
  • Thumbnail for Hydrazine (antidepressant)
    the 1950s and 1960s. Most have been withdrawn due to toxicity, namely hepatotoxicity, but a few still remain in clinical use. Tranylcypromine, a structurally...
    2 KB (162 words) - 17:14, 22 September 2024
  • Thumbnail for Toxicity
    organism, such as a cell (cytotoxicity) or an organ such as the liver (hepatotoxicity). Sometimes the word is more or less synonymous with poisoning in everyday...
    30 KB (3,274 words) - 10:06, 15 September 2024
  • Thumbnail for Scleroderma
    (US) Malignancies, injection site reactions, blood clots, lymphopenia, hepatotoxicity and infections. Azathioprine Purine analogue that inhibits lymphocyte...
    38 KB (3,293 words) - 18:29, 29 August 2024
  • Thumbnail for Niacin
    fatal or non-fatal strokes. Prescription niacin was shown to cause hepatotoxicity and increase risk of type 2 diabetes. Niacin prescriptions in the U...
    92 KB (8,792 words) - 14:49, 24 September 2024
  • Nicotine gum is a chewing gum containing the active ingredient nicotine polacrilex. It is a type of nicotine replacement therapy (NRT) used alone or in...
    17 KB (1,871 words) - 13:28, 26 May 2024
  • Thumbnail for Rosiglitazone
    Rosiglitazone (trade name Avandia) is an antidiabetic drug in the thiazolidinedione class. It works as an insulin sensitizer, by binding to the PPAR in...
    57 KB (5,953 words) - 05:49, 12 October 2024
  • Thumbnail for Erythromycin
    stenosis. Erythromycin estolate has been associated with reversible hepatotoxicity in pregnant women in the form of elevated serum glutamic-oxaloacetic...
    42 KB (3,900 words) - 21:44, 21 September 2024
  • Thumbnail for Anabolic steroid
    and 17%), with hepatotoxicity. In contrast, testosterone esters have only extremely rarely or never been associated with hepatotoxicity, and other non-17α-alkylated...
    209 KB (21,568 words) - 16:45, 2 October 2024
  • liver damage can be attributed to a particular medication. Determining hepatotoxicity (toxic effects of a substance on the liver) remains a major challenge...
    3 KB (258 words) - 14:59, 28 July 2024
  • Thumbnail for Valerian (herb)
    of this uncertainty and the potential for toxicity in the fetus and hepatotoxicity in the mother, valerian use is discouraged during pregnancy. Headache...
    20 KB (2,024 words) - 01:44, 5 October 2024
  • Thumbnail for Electronic waste
    degradation. Studies in mice have found the following health effects: Hepatotoxicity, developmental toxicity, immunotoxicity, hormonal effects and carcinogenic...
    153 KB (16,033 words) - 11:38, 24 September 2024
  • Thumbnail for Zafirlukast
    but serious side effects like acute liver injury. Zafirlukast-induced hepatotoxicity generally occurs within the first 2–6 months of initiating therapy,...
    26 KB (2,484 words) - 08:02, 4 September 2024
  • Thumbnail for Ketoconazole
    analogue, male-limited precocious puberty. In any case, the risk of hepatotoxicity with ketoconazole limits its use in all of these indications, especially...
    50 KB (4,379 words) - 21:52, 16 September 2024
  • Thumbnail for Drostanolone propionate
    fluid retention. Drostanolone propionate is not known to pose a risk of hepatotoxicity. Drostanolone propionate is a prodrug of drostanolone. Like other AAS...
    16 KB (1,277 words) - 16:55, 21 December 2023
  • Thumbnail for Nimesulide
    risk of liver toxicity, including liver failure. Despite its risk of hepatotoxicity, a 2012 evaluation by the European Medicines Agency (EMA) concluded...
    19 KB (1,789 words) - 20:47, 17 September 2024
  • Thumbnail for Kavalactone
    through use of probe drugs to measure inhibition. Its anxiolytic and hepatotoxicity activities have been investigated. The major kavalactones (except for...
    11 KB (867 words) - 01:33, 13 September 2024
  • Thumbnail for Rumack–Matthew nomogram
    half-life is more than 4 hours, then treatment is necessary to prevent hepatotoxicity and liver failure. The original line, sometimes referred to as the Rumack–Matthew...
    5 KB (488 words) - 18:45, 24 September 2024
  • Thumbnail for Oxandrolone
    many[who?] valued oxandrolone's supposed[clarification needed] low hepatotoxicity relative to most other orally active AASs. Like other AASs, oxandrolone...
    47 KB (4,522 words) - 20:23, 12 October 2024
  • Thumbnail for Methocarbamol
    indicators, such as serum transaminase (AST/ALT) levels, to confirm hepatotoxicity. Although unlikely, it is impossible to rule out that methocarbamol...
    26 KB (2,353 words) - 05:32, 30 September 2024
  • Thumbnail for N-Nitrosodimethylamine
    volatile yellow oil. NDMA has attracted wide attention as being highly hepatotoxic and a known carcinogen in laboratory animals. Of more general concern...
    25 KB (2,372 words) - 07:30, 21 September 2024
  • Thumbnail for Ginseng
    potential interaction has been reported with imatinib, resulting in hepatotoxicity, and with lamotrigine. The common ginsengs (P. ginseng and P. quinquefolia)...
    32 KB (3,204 words) - 03:21, 17 October 2024