Homology-directed repair (HDR) is a mechanism in cells to repair double-strand DNA lesions. The most common form of HDR is homologous recombination. The...
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form of Genome Editing). It is based on the natural DNA-repair mechanism of Homology Directed Repair (HDR), including Homologous Recombination. Gene targeting...
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locus stimulates lysostaphin and human lysozyme gene addition by homology-directed repair and derive secrete lysostaphin cows. The ability to precisely manipulate...
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modification by one of two methods. Knock-in mutations, facilitated via homology directed repair (HDR), is the traditional pathway of targeted genomic editing approaches...
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Epigenetics (section DNA repair)
Morano A, Lee B, Di Pardo A, et al. (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal...
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fused to Cas9 to covalently link a DNA repair template to Cas9, resulting in increased homology-directed repair in human cells Similar to the approach...
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Non-homologous end joining (category DNA repair)
homologous template, in contrast to homology directed repair (HDR), which requires a homologous sequence to guide repair. NHEJ is active in both non-dividing...
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"Targeted DNA methylation by homology-directed repair in mammalian cells. Transcription reshapes methylation on the repaired gene". Nucleic Acids Res. 42...
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Genome editing (redirect from Homology-directed recombination)
the restriction endonucleases (FokI and Cas), and the repair of DSBs through homology-directed recombination (HDR) or non-homologous end joining (NHEJ)...
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digital photography High-dynamic-range video, in video Homology directed repair, a DNA repair system in cells Hot dry rock, a form of geothermal energy...
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repair pathways: theta-mediated end joining (TMEJ). Most double-strand breaks are repaired by non-homologous end joining (NHEJ) or homology directed repair...
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Homology directed repair can also introduce foreign DNA at the DSB as the transfected double-stranded sequences are used as templates for the repair enzymes...
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used to edit genomes using non-homologous end joining (NHEJ) and homology directed repair. The CRISPR/Cas9 system (CRISPR – Clustered Regularly Interspaced...
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Shelterin (section Repression of DNA repair mechanisms)
damage-signaling pathways that may lead to non-homologous end joining (NHEJ), homology directed repair (HDR), end-to-end fusions, genomic instability, senescence, or...
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tangible, i.e., the use of ChIP and gene sequence. Homology directed repair (HDR) is a technique repairs breaks or lesions in DNA molecules. The most common...
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Marion; Mantegazza, Otho; Weber, Andreas P. M. (5 April 2018). "Homology-Directed Repair of a Defective Glabrous Gene in Arabidopsis With Cas9-Based Gene...
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High-risk mutations, which disable an important error-free DNA repair process (homology directed repair), significantly increase the person's risk of developing...
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Chiariotti L, Gottesman ME, Avvedimento EV (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genet. 3 (7): e110. doi:10.1371/journal...
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specific nucleotide sequence to repair the host DNA by (homology directed repair) HDR which is a natural nucleic acid repair system. SDN3 uses a large stretch...
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Synthesis-dependent strand annealing (SDSA) is a major mechanism of homology-directed repair of DNA double-strand breaks (DSBs). Although many of the features...
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Morano A, Lee B, Di Pardo A, et al. (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal...
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Morano A, Lee B, Di Pardo A, et al. (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal...
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Chromosomal crossover (section DNA repair theory)
unbalanced recombination is the repair of double-strand breaks (DSBs). DSBs are often repaired using homology directed repair, a process which involves invasion...
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Morano A, Lee B, Di Pardo A, et al. (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal...
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Marion; Mantegazza, Otho; Weber, Andreas P. M. (5 April 2018). "Homology-Directed Repair of a Defective Glabrous Gene in Arabidopsis With Cas9-Based Gene...
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"Targeted DNA methylation by homology-directed repair in mammalian cells. Transcription reshapes methylation on the repaired gene". Nucleic Acids Research...
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end joining (NHEJ) or homology-directed repair (HDR) to fix DNA breaks, while the prime editing system employs DNA mismatch repair. This is an important...
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G2 phase (section Homologous recombinational repair)
effectively stalling the cell in G2 until the damage is repaired by mechanisms such as homology-directed repair (see above). Long-term maintenance of the G2 arrest...
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Homologous recombination (redirect from Recombinational repair)
ability to repair DNA by HR. Chromosomal crossover Homology directed repair Thompson LH, Schild D (June 2001). "Homologous recombinational repair of DNA ensures...
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Gottesman, Max E; Avvedimento, Enrico V (6 July 2007). "DNA Damage, Homology-Directed Repair, and DNA Methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal...
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