Hsp104 is a heat-shock protein. It is known to reverse toxicity of mutant α-synuclein, TDP-43, FUS, and TAF15 in yeast cells. Conserved in prokaryotes...

to a prion negative phenotype). This is the result of inhibition of the Hsp104 chaperone protein known to play an important role in prion fiber fragmentation...

classified based on their observed molecular weights into Hsp60, Hsp70, Hsp90, Hsp104, and small Hsps. The Hsp60 family of protein chaperones are termed chaperonins...

[PSI+] prion aggregates are formed by small Sup35 polymers fragmented by Hsp104". J Biol Chem. 278 (49): 49636–43. doi:10.1074/jbc.M307996200. PMID 14507919...

of steroid receptors and transcription factors 100 kDa ClpB, ClpA, ClpX Hsp104 (CLPB) Unfolding of insoluble protein aggregates; co-factor of DnaK/Hsp70...

refolding to the prion configuration is assisted by chaperone proteins such as Hsp104. All known prions induce the formation of an amyloid fold, in which the...

[PSI+] prion aggregates are formed by small Sup35 polymers fragmented by Hsp104". The Journal of Biological Chemistry. 278 (49): 49636–43. doi:10.1074/jbc...

heritable forms of protein. Because of the action of chaperones, especially Hsp104, proteins that code for [PSI+] and [URE3] can convert from non-prion to...

coli and Ssa1-Ydj1/Sis1-Sse1/Fe1 in yeast) and Hsp100 (ClpB in E. coli and Hsp104 in yeast) chaperones for protein disaggregation and refolding. Hsp70 interacts...

thermotolerance in Saccharomyces cerevisiae without heat shock protein hsp104 and in the absence of protein synthesis". FEBS Letters. 288 (1–2): 86–90...

Michaelis, S.; Brodsky, J. L. (2018). "Substrate Insolubility Dictates Hsp104-Dependent Endoplasmic-Reticulum-Associated Degradation". Molecular Cell...

Nups. Several of these inducible genes, including GAL1, INO1, TSA2, and HSP104 contain gene recruitment sequences (GRSs) found in the promoter, which are...

have functions other than proteolysis. ClpB (human CLPB "Hsp78", yeast Hsp104) break up insoluble protein aggregates in conjunction with DnaK/Hsp70. They...

potassium transport mutant: identification of a mammalian member of the Clp/HSP104 family". Gene. 152 (2): 157–63. doi:10.1016/0378-1119(94)00697-Q. PMID 7835694...

[PSI+] prion aggregates are formed by small Sup35 polymers fragmented by Hsp104". Journal of Biological Chemistry. 278 (49): 49636–43. doi:10.1074/jbc.M307996200...

the disaggregase chaperone, AAA protein HSP104, localizes to the IPOD. It is yet to be determined if HSP104 functions in the IPOD or is simply sequestered...