• Thumbnail for Hyaluronidase
    Hyaluronidases are a family of enzymes that catalyse the degradation of hyaluronic acid. Karl Meyer classified these enzymes in 1971, into three distinct...
    31 KB (2,895 words) - 10:05, 2 June 2024
  • Efgartigimod alfa/hyaluronidase, sold under the brand name Vyvgart Hytrulo, is a coformulation medication used for the treatment of generalized myasthenia...
    6 KB (425 words) - 07:18, 25 June 2024
  • Pertuzumab/trastuzumab/hyaluronidase, sold under the brand name Phesgo, is a fixed-dose combination medication to treat adults with HER2-positive breast...
    12 KB (966 words) - 07:37, 1 July 2024
  • Daratumumab/hyaluronidase, sold under the brand name Darzalex Faspro, is a fixed-dose combination medication for the treatment of adults with newly diagnosed...
    11 KB (913 words) - 02:23, 5 November 2023
  • Trastuzumab/hyaluronidase, sold under the brand name Herceptin SC among others, is a fixed-dose combination medication for the treatment of HER2-overexpressing...
    11 KB (703 words) - 18:13, 27 March 2024
  • Thumbnail for Rituximab
    Waldenström's macroglobulinemia, a type of NHL. Rituximab in combination with hyaluronidase human, sold under the brand names MabThera SC and Rituxan Hycela, is...
    50 KB (4,348 words) - 03:50, 1 July 2024
  • Thumbnail for Hyaluronidase deficiency
    Hyaluronidase deficiency is a condition caused by mutations in the HYAL1 gene, and is characterized by multiple soft-tissue masses.: 544  As hyaluronidase...
    3 KB (147 words) - 13:03, 4 June 2024
  • Thumbnail for Halozyme
    primarily focused on its proprietary and patented recombinant human hyaluronidase enzyme, rHuPH20. The company's development pipeline is concentrated...
    10 KB (1,016 words) - 17:35, 14 May 2024
  • Thumbnail for Glycocalyx
    sulphate and hyaluronan can be shed of the endothelial layer by enzymes. Hyaluronidase, hepararanse/heparinase, matrix and membrane-type matrix metalloproteases...
    19 KB (2,190 words) - 09:59, 2 June 2024
  • Thumbnail for Streptococcus pyogenes
    PMID 22050223. S2CID 207441558. Starr CR, Engleberg NC (January 2006). "Role of hyaluronidase in subcutaneous spread and growth of group A streptococcus". Infection...
    40 KB (3,950 words) - 04:18, 20 May 2024
  • Thumbnail for Cutis verticis gyrata
    acid)). Two published medical journals appear to show Hyaluronidase injections (Hyaluronidase is an enzyme used to dissolve hyaluronic acid which is...
    11 KB (1,105 words) - 12:59, 2 June 2024
  • Thumbnail for Bee sting
    phospholipase A2, hyaluronidase and acid phosphatase. The three proteins in honeybee venom that are important allergens are phospholipase A2, hyaluronidase and acid...
    14 KB (1,582 words) - 19:43, 29 June 2024
  • Thumbnail for HYAL1
    Hyaluronidase-1 is an enzyme that in humans is encoded by the HYAL1 gene. This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly...
    17 KB (2,078 words) - 10:05, 2 June 2024
  • Thumbnail for Acrosome
    placental mammals, the acrosome contains degradative enzymes (including hyaluronidase and acrosin). These enzymes break down the outer membrane of the ovum...
    4 KB (423 words) - 09:32, 16 February 2024
  • Thumbnail for Hyaluronic acid
    degraded by a family of enzymes called hyaluronidases. In humans, there are at least seven types of hyaluronidase-like enzymes, several of which are tumor...
    50 KB (5,491 words) - 13:36, 29 June 2024
  • bruised. Hyaluronic acid "bruising" may be treated using injections of hyaluronidase enzyme around the location. Other common medication-specific side effects...
    22 KB (2,581 words) - 08:38, 3 December 2023
  • Thumbnail for Staphylococcus aureus
    fibrinogen to fibrin to cause clots which is important in skin infections. Hyaluronidase (also known as spreading factor) breaks down hyaluronic acid and helps...
    114 KB (12,732 words) - 18:27, 23 May 2024
  • variety of enzymes which cause damage to host tissues. Enzymes include hyaluronidase, which breaks down the connective tissue component hyaluronic acid;...
    15 KB (1,871 words) - 07:36, 25 March 2024
  • Thumbnail for Hyaluromycin
    family of antibiotics that inhibits the hydrolysis of hyaluronic acid by hyaluronidase. It has been isolated from cultures of Streptomyces hyaluromycini. Harunari...
    3 KB (113 words) - 13:16, 19 June 2024
  • Thumbnail for Alternative splicing
    instance, the figure to the right shows 3 spliceforms from the mouse hyaluronidase 3 gene. Comparing the exonic structure shown in the first line (green)...
    62 KB (7,809 words) - 17:56, 21 May 2024
  • present in myasthenia gravis. It is also available coformulated with hyaluronidase. The most common side effects include respiratory tract infections,...
    17 KB (1,326 words) - 07:06, 25 June 2024
  • Thumbnail for Snake
    affect the body in different ways. Almost all snake venom contains hyaluronidase, an enzyme that ensures rapid diffusion of the venom.: 243  Venomous...
    151 KB (15,099 words) - 19:40, 3 July 2024
  • Acetoin Negative Acid Phosphatase Variable Alkaline Phosphatase Positive Hyaluronidase Negative β-D-glucosidase Positive Leucine aminopeptidase Positive Neuraminidase...
    6 KB (551 words) - 03:52, 23 October 2023
  • Thumbnail for Vespula
    subgenus of Vespula The venom of Vespula is mostly composed of antigen 5, hyaluronidase, and phospholipase.​ A high degree of similarity occurs between immunogenic...
    9 KB (738 words) - 01:28, 7 November 2023
  • Thumbnail for HYAL2
    Hyaluronidase-2 is a multifunctional protein, previously thought to only possess acid-active hyaluronan-degrading enzymatic function. In humans it is...
    10 KB (1,152 words) - 16:25, 1 February 2024
  • under the brand name Longidaze, is a conjugate of proteolytic enzyme hyaluronidase with high- molecular weight copolymer that forms a component of combination...
    22 KB (1,707 words) - 19:18, 2 July 2024
  • Thumbnail for Corona radiata (embryology)
    Graafian follicle. For fertilization to occur, sperm cells rely on hyaluronidase (an enzyme found in the acrosome of spermatozoa) to disperse the corona...
    3 KB (247 words) - 05:54, 27 June 2024
  • Thumbnail for Lysosome
    mucopolysaccharides E- Lysozymes Bacterial cell walls and mucopolysaccharides F- Hyaluronidase Hyaluronic acids, chondroitin sulfates H- Arylsulphatase Organic sulfates...
    43 KB (4,709 words) - 17:51, 12 June 2024
  • Thumbnail for Oleanolic acid
    female rats. Oleanolic acid is also used as standard for comparison of hyaluronidase, elastase and matrix-metalloproteinase-1 inhibition of other substances...
    12 KB (913 words) - 17:08, 26 March 2024
  • Thumbnail for Fertilisation
    the GalT initiates the acrosome reaction. This process releases the hyaluronidase that digests the matrix of hyaluronic acid in the vestments around the...
    45 KB (5,197 words) - 08:18, 31 May 2024