Ibritumomab tiuxetan (pronounced /ɪbrɪˈtuːmoʊmæb taɪˈʌksɛtæn/), sold under the trade name Zevalin, is a monoclonal antibody radioimmunotherapy treatment...
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Radioligand (section Iodine-131 tositumomab (Bexxar) and Zevalin (90Y-ibritumomab tiuxetan) for non-Hodgkin's lymphoma)
A radioligand is a microscopic particle which consists of a therapeutic radioactive isotope and the cell-targeting compound - the ligand. The ligand is...
36 KB (4,347 words) - 03:05, 20 April 2024
target of the mAbs rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the...
26 KB (2,953 words) - 22:19, 25 June 2024
Iodine-131-sodium iodide hyperthyroidism and thyroid cancer Yttrium-90-ibritumomab tiuxetan (Zevalin) and Iodine-131-tositumomab (Bexxar) refractory lymphoma...
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Tositumomab/iodine (131I) tositumomab V10XX01 Sodium phosphate (32P) V10XX02 Ibritumomab tiuxetan (90Y) V10XX03 Radium (223Ra) dichloride V10XX04 Lutetium (177Lu)...
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Yttriga yttrium (Y 90) clivatuzumab tetraxetan (USAN) yttrium (Y 90) ibritumomab tiuxetan (INN) yttrium bromatum yttrium fluoratum yttrium iodide yttrium metallicum...
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triaminopentacarboxylate scaffold for metal ions. In ibritumomab tiuxetan, the chelator tiuxetan is a modified version of DTPA whose carbon backbone contains...
15 KB (1,657 words) - 23:16, 18 August 2023
drugs such as Yttrium Y 90-DOTA-tyr3-octreotide and Yttrium Y 90 ibritumomab tiuxetan for the treatment of various cancers, including lymphoma, leukemia...
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Fusilev (levoleucovorin), Folotyn (pralatexate injection), Zevalin (ibritumomab tiuxetan), Marqibo (vincristine sulfate LIPOSOME injection), Beleodaq (belinostat)...
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Other B cell-destroying monoclonal antibodies such as alemtuzumab, ibritumomab tiuxetan and I-131 tositumomab may be considered for refractory cases. Interferon-alpha...
57 KB (7,246 words) - 00:23, 27 June 2024
mitoxantrone, methotrexate, prednisone, rituximab, vincristine and 90Y-ibritumomab tiuxetan.[citation needed] One combination for stage III/IV relapsed or refractory...
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2002, the United States Food and Drug Administration (FDA) approved ibritumomab tiuxetan (Zevalin), which is an anti-CD20 monoclonal antibody conjugated to...
113 KB (13,531 words) - 22:40, 29 June 2024
biopsy – incomplete Freund's adjuvant – indinavir – indium In 111 ibritumomab tiuxetan – indium In 111 pentetreotide – indole-3-carbinol – indolent lymphoma...
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radiolabeling process, which is tailored to the desired product. Ibritumomab Tiuxetan; Zevalin - For dosimetry estimates prior to 90Y immunotherapy for...
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infection Sintilimab human PD-1 squamous cell non-small cell lung cancer Ibritumomab tiuxetan Zevalin mab mouse CD20 Y non-Hodgkin's lymphoma Icrucumab mab human...
135 KB (4,054 words) - 22:35, 2 July 2024
131I treatment of thyroid cancer, and radioimmunotherapy with 90Y ibritumomab tiuxetan (Zevalin) & 131I tositumomab (Bexxar) therapy of low-grade non-Hodgkin's...
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TaiMed Biologics 3/6/18 intravenous humanized CD4 HIV 761065 Link ibritumomab tiuxetan Zevalin Spectrum Pharmaceuticals 2/19/2002 intravenous murine, radioimmunotherapy...
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as B-cell receptor (see adjacent figure) signaling blockers and ibritumomab tiuxetan (Zevlin) are being tested in clinical trials for MZL. These trials...
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neoplasm or is not accessible in normal cells. 131I tositumomab and 90Y ibritumomab tiuxetan were the first agents of radioimmunotherapy, and they were approved...
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A J (28 May 2007). "Radioimmunotherapy for B-cell lymphoma: Y90 ibritumomab tiuxetan and I131 tositumomab". Oncogene. 26 (25): 3614–3628. doi:10.1038/sj...
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Tositumomab (Bexxar). Anti-CD20 conjugated with radionuclide iodine-131 Ibritumomab tiuxetan (Zevalin). Anti-CD20 conjugated with radioactive isotope (either...
20 KB (2,453 words) - 10:36, 1 June 2024
in binding to CD20; two radioimmunotherapy monoclonal antibodies, Ibritumomab tiuxetan and Tositumomab that bind CD20 to deliver radiation from their attached...
22 KB (2,669 words) - 05:05, 4 January 2024
cytokine release syndrome, hypersensitivity and electrolyte anomalies. Ibritumomab tiuxetan IV CD20 antibody bound with the radioactive isotope, 90Y, induces...
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of lymphoma radioimmunotherapy and the eventual FDA approval of Ibritumomab tiuxetan. Throughout his career, Press continued to advance and refine such...
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Bectumomab Blinatumomab Capromab pendetide Detumomab Edrecolomab Ibritumomab tiuxetan Igovomab Lilotomab Minretumomab Mitumomab Nacolomab tafenatox Moxetumomab...
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Bectumomab Blinatumomab Capromab pendetide Detumomab Edrecolomab Ibritumomab tiuxetan Igovomab Lilotomab Minretumomab Mitumomab Nacolomab tafenatox Moxetumomab...
4 KB (241 words) - 11:41, 22 April 2022
Bectumomab Blinatumomab Capromab pendetide Detumomab Edrecolomab Ibritumomab tiuxetan Igovomab Lilotomab Minretumomab Mitumomab Nacolomab tafenatox Moxetumomab...
3 KB (129 words) - 01:04, 19 July 2023