Induced-self antigen is a marker of abnormal self, which can be recognized upon infected (in particular, virus-infected) and transformed cells. Therefore...

antibody is called the antigen-antibody reaction. Antigen can originate either from within the body ("self-protein" or "self antigens") or from the external...

induced by antigens given by mouth and exposed to the gut mucosa and its associated lymphoid tissues. The intestine harbours many non-self-antigens that...

foreign antigen in the presence of self MHC. They will differentiate into either CD4+ or CD8+ depending on which MHC is associated with the antigen presented...

antibodies to that specific antigen. Self-antigens are suppressed by regulatory T cells. Predicting which (fragments of) antigens will be presented to the...

topics. Normal proteins in the body are not antigenic because of self-tolerance, a process in which self-reacting cytotoxic T lymphocytes (CTLs) and...

Antigen-antibody interaction, or antigen-antibody reaction, is a specific chemical interaction between antibodies produced by B cells of the white blood...

recognizing fragments of antigen as peptides bound to major histocompatibility complex (MHC) molecules. The binding between TCR and antigen peptides is of relatively...

Immunogenicity is the ability of a foreign substance, such as an antigen, to provoke an immune response in the body of a human or other animal. It may...

An antigen-presenting cell (APC) or accessory cell is a cell that displays an antigen bound by major histocompatibility complex (MHC) proteins on its surface;...

stage of antigen presentation pathways. This process involves two distinct pathways for processing of antigens from an organism's own (self) proteins...

function of MHC molecules: binding an antigen derived from self-proteins, or from pathogens, and bringing the antigen presentation to the cell surface for...

Immunotoxicology Immunotoxin Immunotransplant Indoleamine 2,3-dioxygenase Induced-self antigen Inflammasome Inflammation Inflammatory reflex Innate immune system...

drug-induced cell death in human triple-negative breast cancer. Since NK cells recognize target cells when they express nonself HLA antigens (but not self)...

Activation-Induced Cell Death in T Cells and Autoimmunity. Cell Mol Immunol. 1(3):186-92 Kabelitz D, Janssen O. (1997), Antigen-induced death of T-lymphocytes...

response induced by antigen-presenting cells of the recipient against the foreign MiHA cells. Because of this, Bevan implied that these antigen presenting...

leukemia effect (GVL). The recognition of a mature T cell to this self antigen should not induce an immune response. During thymic selection occurring in the...

The thymocyte must also ensure that it does not react adversely to "self" antigens, called negative selection. If both positive and negative selection...

system. Conversely, non-self molecules are those recognized as foreign molecules. One class of non-self molecules are called antigens (originally named for...

cells recognize only fragmented antigens displayed on cell surfaces, antigen processing must occur before the antigen fragment can be recognized by a...

reaction with eosinophilia and systemic symptoms (DRESS), also termed drug-induced hypersensitivity syndrome (DIHS), is a rare reaction to certain medications...

An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells...

antibodies to foreign proteins (antigens) but not to human proteins (autoantigens). In some cases, antibodies to human antigens are produced; these are known...

nsp3 and nsp4). This sequence encodes the protein of interest, used as an antigen in the case of vaccines or for protein replacement therapies. The gene...

Th1 cells requires interleukin-12-induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose". Immunity. 31 (2): 209–219. doi:10...

the central nervous system (CNS). MICA plays the role of stress-induced self-antigen and serves as a ligand for the KLRK1/NKG2D killer activation receptor...

Human leukocyte antigens (HLA) began as a list of antigens identified as a result of transplant rejection. The antigens were initially identified by categorizing...

and present antigens to αβ T cells. This leads to turn of naïve CD4+ and CD8+ αβ T cells into effector cells. The differentiation, induced by γδ T-APC...

recognize self antigens as "self", is a loss of immunological tolerance, the ability for the immune system to discriminate between self and non-self. Other...

subpopulation of T cells that modulate the immune system, maintain tolerance to self-antigens, and prevent autoimmune disease. Treg cells are immunosuppressive and...